Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with Target = 'T-cell surface glycoprotein CD4'
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50077220(Cosalane analogue | 3'',3'''-Dichloro-4'',4'''-bis...)
Affinity DataEC50: >2.90E+4nMAssay Description:In vitro inhibition of cytopathic effect was determined against HIV-2 ROD in MT-4 cells using MTS cytoprotection assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50077218(Cosalane analogue | 3'',3'''-Dichloro-4'',4'''-bis...)
Affinity DataEC50: >3.70E+4nMAssay Description:In vitro inhibition of cytopathic effect was determined against HIV-2 ROD in MT-4 cells using MTS cytoprotection assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50093807(2-(3-Chloro-5-{1-[3-chloro-5-(1,3-dicarboxy-propyl...)
Affinity DataEC50:  6.96E+4nMAssay Description:In vitro inhibition of cytopathic effect was determined against HIV-2 ROD in MT-4 cells using MTS cytoprotection assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50093808(5-{1-[3-carboxylato-4-(3-carboxy-2-methoxybenzylox...)
Affinity DataEC50: >1.25E+5nMAssay Description:In vitro inhibition of cytopathic effect was determined against HIV-2 ROD in MT-4 cells using MTS cytoprotection assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50092094(3'',3'''-Dichloro-5'',5'''-dicarboxy-4'',4'''-di[p...)
Affinity DataEC50: >1.00E+5nMAssay Description:In vitro inhibition of cytopathic effect was determined against HIV-2 ROD in MT-4 cells using MTS cytoprotection assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50093810((S)-2-(3-Chloro-5-{1-[3-chloro-5-((S)-1,2-dicarbox...)
Affinity DataEC50:  1.22E+5nMAssay Description:In vitro inhibition of cytopathic effect was determined against HIV-2 ROD in MT-4 cells using MTS cytoprotection assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50097417(3'',3'''-Dichloro-5'',5'''-dicarboxy-4'',4'''-di[p...)
Affinity DataEC50:  7.04E+4nMAssay Description:In vitro inhibition of cytopathic effect was determined against HIV-2 ROD in MT-4 cells using MTS cytoprotection assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50092093(3'',3'''-Dichloro-5'',5'''-dicarboxy-4'',4'''-di[p...)
Affinity DataEC50:  8.38E+4nMAssay Description:In vitro inhibition of cytopathic effect was determined against HIV-2 ROD in MT-4 cells using MTS cytoprotection assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50093814(2-(5-{1-{3-[1-carboxy-2-phenyl-(1S)-ethylcarbamoyl...)
Affinity DataEC50: >6.20E+4nMAssay Description:In vitro inhibition of cytopathic effect was determined against HIV-2 ROD in MT-4 cells using MTS cytoprotection assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50036146(5-{1-(3-carboxy-5-chloro-4-hydroxyphenyl)-4-[1-(1,...)
Affinity DataEC50:  4.00E+3nMAssay Description:In vitro inhibition of cytopathic effect was determined against HIV-2 ROD in MT-4 cells using MTS cytoprotection assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50069212(Cosalane analogue | 3'',3'''-Dichloro-4'',4'''-bis...)
Affinity DataEC50:  2.20E+4nMAssay Description:In vitro inhibition of cytopathic effect was determined against HIV-2 ROD in MT-4 cells using MTS cytoprotection assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50093809(2-(3-Chloro-5-{1-[3-chloro-5-(1,3-dicarboxy-propyl...)
Affinity DataEC50:  7.30E+4nMAssay Description:In vitro inhibition of cytopathic effect was determined against HIV-2 ROD in MT-4 cells using MTS cytoprotection assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50092091(3'',3'''-Dichloro-5'',5'''-dicarboxy-4'',4'''-di[p...)
Affinity DataEC50: >9.50E+4nMAssay Description:In vitro inhibition of cytopathic effect was determined against HIV-2 ROD in MT-4 cells using MTS cytoprotection assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50093811((S)-2-(5-{1-[3-((S)-1-Carboxy-3-methyl-butylcarbam...)
Affinity DataEC50: >1.25E+5nMAssay Description:In vitro inhibition of cytopathic effect was determined against HIV-2 ROD in MT-4 cells using MTS cytoprotection assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50093813((5-{1-[3-(Carboxymethyl-carbamoyl)-5-chloro-4-hydr...)
Affinity DataEC50: >1.25E+5nMAssay Description:In vitro inhibition of cytopathic effect was determined against HIV-2 ROD in MT-4 cells using MTS cytoprotection assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50097416(Cosalane analogue | CHEMBL383913)
Affinity DataEC50: >6.60E+4nMAssay Description:In vitro inhibition of cytopathic effect was determined against HIV-2 ROD in MT-4 cells using MTS cytoprotection assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50093812(3-(5-{1-[3-(2-Carboxy-ethylcarbamoyl)-5-chloro-4-h...)
Affinity DataEC50:  1.20E+5nMAssay Description:In vitro inhibition of cytopathic effect was determined against HIV-2 ROD in MT-4 cells using MTS cytoprotection assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50092092(3'',3'''-Dichloro-5'',5'''-dicarboxy-4'',4'''-di[p...)
Affinity DataEC50: >1.25E+5nMAssay Description:In vitro inhibition of cytopathic effect was determined against HIV-2 ROD in MT-4 cells using MTS cytoprotection assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50217029((S)-2-((2S,3S)-2-(2-((S)-2-((S)-6-amino-2-(2-(naph...)
Affinity DataKd:  6.20E+4nMAssay Description:Binding affinity to CD4 by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50217027(((S)-1-((2S,3R)-2-(2-((S)-2-((S)-6-amino-2-(2-(nap...)
Affinity DataKd:  1.60E+4nMAssay Description:Binding affinity to CD4 by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50217028(ethyl 2-((((S)-1-((2S,3R)-2-(2-((S)-2-((S)-6-amino...)
Affinity DataKd:  2.60E+4nMAssay Description:Binding affinity to CD4 by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50217026(tert-Butyl-carbamic acid (S)-1-{(2S,3S)-2-[2-((S)-...)
Affinity DataKd:  6.00E+3nMAssay Description:Binding affinity to CD4 by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50217023((S)-2-((2S,3R)-2-(2-((S)-2-((S)-6-amino-2-(2-(quin...)
Affinity DataKd:  1.30E+4nMAssay Description:Binding affinity to CD4 by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50217025(((S)-1-((2S,3R)-2-(2-((S)-2-((S)-6-amino-2-(2-(nap...)
Affinity DataKd:  3.50E+4nMAssay Description:Binding affinity to CD4 by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50371093(CHEMBL1791396)
Affinity DataKd:  6.00E+6nMAssay Description:Binding affinity to CD4 by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50217022(O-((S)-1-((2S,3R)-2-(2-((S)-2-((S)-6-amino-2-(2-(n...)
Affinity DataKd:  2.70E+4nMAssay Description:Binding affinity to CD4 by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50217021(tert-butyl-carbamic acid (S)-2-{(2S,3S)-2-[2-((S)-...)
Affinity DataKd:  2.00E+4nMAssay Description:Binding affinity to CD4 by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50217020(adamantan-1-yl-carbamic acid (S)-2-{(2S,3R)-2-[2-(...)
Affinity DataKd:  8.00E+4nMAssay Description:Binding affinity to CD4 by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50217019(((S)-1-((2S,3R)-2-(2-((S)-2-((S)-6-amino-2-(2-(qui...)
Affinity DataKd:  2.60E+4nMAssay Description:Binding affinity to CD4 by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50097415(Cosalane analogue | CHEMBL216469)
Affinity DataEC50:  1.99E+4nMAssay Description:In vitro inhibition of cytopathic effect was determined against HIV-2 ROD in MT-4 cells using MTS cytoprotection assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50123449(Chloropeptin II | CHEMBL437996 | ISOCOMPLESTATIN)
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration against CD4-gp120 binding in the absence of fetal bovine serum (FBS); Range is 0.13-0.5 uMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50548974(CHEMBL4747494)
Affinity DataIC50: 130nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50366855(Chloropeptin | CHEMBL525803)
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration against CD4-gp120 binding in the absence of fetal bovine serum (FBS); Range is 0.13-0.5 uMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50123450(Chloropeptin I analogue | CHEMBL3143464)
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration against CD4-gp120 binding in the absence of fetal bovine serum (FBS); Range is 0.13-0.5 uMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50545414(CHEMBL1852155)
Affinity DataIC50: 210nMAssay Description:Inhibition of FITC-tagged human CD4 expressed in human SUP-T1 cells after 72 hrs by FACS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50548980(CHEMBL4791666)
Affinity DataIC50: 220nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50545414(CHEMBL1852155)
Affinity DataIC50: 330nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50548973(CHEMBL4746252)
Affinity DataIC50: 420nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50548976(CHEMBL4750983)
Affinity DataIC50: 540nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50548977(CHEMBL4786809)
Affinity DataIC50: 660nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50548978(CHEMBL4748787)
Affinity DataIC50: 740nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50548975(CHEMBL4758659)
Affinity DataIC50: 830nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50548968(CHEMBL4755141)
Affinity DataIC50: 860nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50548969(CHEMBL4783761)
Affinity DataIC50: 950nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50548972(CHEMBL4782080)
Affinity DataIC50: 1.50E+3nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50548979(CHEMBL4785236)
Affinity DataIC50: 1.67E+3nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50548971(CHEMBL4743003)
Affinity DataIC50: 1.88E+3nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50548967(CHEMBL4783030)
Affinity DataIC50: 2.81E+3nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetT-cell surface glycoprotein CD4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50548970(CHEMBL4750160)
Affinity DataIC50: 9.30E+3nMAssay Description:Binding affinity to signal peptide of human CD4-YFP expressed in CHO-K1 cells assessed down-modulation of CD4 surface expression incubated for 24 hrs...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed