Compile Data Set for Download or QSAR
Report error Found 289 Enz. Inhib. hit(s) with Target = 'Stimulator of interferon genes protein [1-379,R71H,G230A,H232R,R293Q]'
LigandPNGBDBM457770(US10738074, Example 1)
Affinity DataEC50:  19nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM457771(2-amino-9-[(1R,6S,8R,9R,14R,16R,17R)-16-(6- amino-...)
Affinity DataEC50:  18.2nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM457772(2-amino-9-[(1R,6R,8R,9S,14R,16R,17R,18R)-16- (6-am...)
Affinity DataEC50:  3.60nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM457773(2-amino-9-[(1S,6R,8R,9R,14R,16R,17R,18R)-16- (6-am...)
Affinity DataEC50:  1.80nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM457774(2-amino-9-[(1R,6S,8R,9R,14R,16R,17R,18R)-16- (6-am...)
Affinity DataEC50: <1nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM457775(2-amino-9-[(1R,6R,8R,9R,14S,16R,17R,18R)-16- (6-am...)
Affinity DataEC50:  2.30nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM457776(2-amino-9- [(1R,6R,8R,9S,13R,14S,16R,17R,18R)-16-(...)
Affinity DataEC50:  45.2nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM457777(2-amino-9- [(1R,6R,8R,9S,13S,14S,16R,17R,18R)-16-(...)
Affinity DataEC50:  102nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM457778(US10738074, Example 9)
Affinity DataEC50:  3.70nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM457779(2-amino-9-[(1S,6S,8R,9R,14R,16R,17R)-16-(6- amino-...)
Affinity DataEC50:  24.4nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM457780(2-amino-9-[(1S,6R,8R,9S,14R,16R,17R,18R)-16- (6-am...)
Affinity DataEC50: <1nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM457781(2-amino-9-[(1R,6S,8R,9R,14S,16R)-16-(6-amino- 9H-p...)
Affinity DataEC50:  674nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM457782(2-amino-9-[(1S,6R,8R,9S,14R,16R,17S,18R)-16- (6-am...)
Affinity DataEC50:  11.2nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM457783(US10738074, Example 14)
Affinity DataEC50:  1.90nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM457784(US10738074, Example 15)
Affinity DataEC50:  23.4nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM457785(US10738074, Example 16 | US10738074, Example 17)
Affinity DataEC50:  12.5nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM457785(US10738074, Example 16 | US10738074, Example 17)
Affinity DataEC50:  1.31E+3nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM457787(US10738074, Example 18)
Affinity DataEC50: <1nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM457789(US10738074, Example 19)
Affinity DataEC50: <1nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM457790(US10738074, Example 20)
Affinity DataEC50: <1nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM457791(US10738074, Example 21)
Affinity DataEC50:  2.90nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM457792(US10738074, Example 25 | 9,9′-[(1R,6R,8R,9R,...)
Affinity DataEC50: <1nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM457792(US10738074, Example 25 | 9,9′-[(1R,6R,8R,9R,...)
Affinity DataEC50: <1nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM457794((1R,6R,8R,9R,14R,16R,17R,18R)-8,16-bis(6- amino-9H...)
Affinity DataEC50:  6.60nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM457795(US10738074, Example 32)
Affinity DataEC50:  1.90nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM457796(2-amino-9- [(1R,6R,8R,9R,14S,16R,17R,18R)-17- amin...)
Affinity DataEC50:  1.60nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM457797(US10738074, Example 34)
Affinity DataEC50: <1nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM50509412(CHEMBL4474321 | US11453697, Example 1)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM573838(US11453697, Example 2 | US11453697, Example 7 | (5...)
Affinity DataEC50:  1.30nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM573839(US11453697, Example 3 | (5R,7R,8R,12aR,14R,15aS,16...)
Affinity DataEC50:  257nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM573840(US11453697, Example 4 | (5R,7R,8R,12aR,14R,15R,15a...)
Affinity DataEC50:  22nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM573841(US11453697, Example 5 | (5R,7R,8S,12aR,14R,15R,15a...)
Affinity DataEC50:  1.10nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM573842(US11453697, Example 6 | (5R,7R,8R,12aR,14R,15R,15a...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM573838(US11453697, Example 2 | US11453697, Example 7 | (5...)
Affinity DataEC50:  1.20nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM573844(US11453697, Example 8 | (5R,7R,8R,12aR,14R,15aS,16...)
Affinity DataEC50:  13.6nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM573845(US11453697, Example 9 | (5R,7R,8R,12aR,14R,15R,15a...)
Affinity DataEC50:  7.20nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM573846(US11453697, Example 10 | (5R,7R,8R,12aR,14R,15aS,1...)
Affinity DataEC50:  4.90nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM573847(US11453697, Example 11 | (5R,7R,8R,12aR,14R,15R,15...)
Affinity DataEC50:  1.20nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM573848(US11453697, Example 12 | (5R,7R,8R,12aR,14R,15R,15...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM573849(US11453697, Example 13 | 2-amino-9- [(5R,7R,8R,12a...)
Affinity DataEC50:  1.5nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM573850(US11453697, Example 14 | 2-amino-9- [(5S,7R,8R,12a...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM573851(US11453697, Example 15 | 2-amino-9- [(5R,7R,8R,12a...)
Affinity DataEC50:  378nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM573852(US11453697, Example 16 | 2-amino-9- [(5S,7R,8R,12R...)
Affinity DataEC50:  12.4nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM573853(US11453697, Example 17 | 2-amino-9- [(2aR,5S,6aS,7...)
Affinity DataEC50:  121nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM573854(US11453697, Example 18 | 2-amino-9-[(5S,7R,8R,12S,...)
Affinity DataEC50:  53.9nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM573855(US11453697, Example 19 | 2-amino-9-[(5S,7R,8R,12aR...)
Affinity DataEC50:  173nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM573856(US11453697, Example 20)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM573857(US11453697, Example 21 | 2-amino-9-[(5S,7R,8R,12aR...)
Affinity DataEC50:  1.30nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM573858(US11453697, Example 22 | 2-amino-9-[(5R,7R,8S,12aR...)
Affinity DataEC50:  4.82E+3nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM573859(US11453697, Example 23 | US11453697, Example 26 | ...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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