Compile Data Set for Download or QSAR
Report error Found 140 Enz. Inhib. hit(s) with Target = 'Spike glycoprotein'
TargetSpike glycoprotein [668-1255](SARS-CoV)
University of Bonn

LigandPNGBDBM428875(med.21724, Compound 2)
Affinity DataEC50:  4.40E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein [668-1255](SARS-CoV)
University of Bonn

LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataEC50:  1.06E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(SARS-CoV)
University of Bonn

LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataEC50:  8.34E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(SARS-CoV)
University of Bonn

LigandPNGBDBM428938(med.21724, Compound 5)
Affinity DataEC50:  3.89E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(SARS-CoV)
University of Bonn

LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataEC50:  1.00E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(MERS-CoV)
University of Bonn

LigandPNGBDBM429291(med.21724, Compound 27)
Affinity DataEC50:  1.27E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(SARS-CoV)
University of Bonn

LigandPNGBDBM429291(med.21724, Compound 27)
Affinity DataEC50:  760nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50568789(Hypocrellin A | Rel-Hypocrellin A)
Affinity DataKd:  38nMAssay Description:Binding affinity to SARS-CoV-2 spike glycoprotein S RBD at 25 degreeC by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50568790(CHEMBL4869623)
Affinity DataKd:  23nMAssay Description:Binding affinity to SARS-CoV-2 spike glycoprotein S RBD at 25 degreeC by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(SARS-CoV)
University of Bonn

LigandPNGBDBM50567444(CHEMBL4873011)
Affinity DataKd:  940nMAssay Description:Binding affinity to SARS-CoV-2 spike glycoprotein S-trimer measured by Surface plasmon resonanceMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50582778(CHEMBL5081268)
Affinity DataKd:  106nMAssay Description:Binding affinity to recombinant SARS-COV2 S-RBD incubated for 5 mins by microscale thermophoresis analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50582779(CHEMBL5081573)
Affinity DataKd:  102nMAssay Description:Binding affinity to recombinant SARS-COV2 S-RBD incubated for 5 mins by microscale thermophoresis analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50582780(CHEMBL5091821)
Affinity DataKd:  245nMAssay Description:Binding affinity to recombinant SARS-COV2 S-RBD incubated for 5 mins by microscale thermophoresis analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50582781(CHEMBL5078837)
Affinity DataKd:  541nMAssay Description:Binding affinity to recombinant SARS-COV2 S-RBD incubated for 5 mins by microscale thermophoresis analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50582782(CHEMBL5088125)
Affinity DataKd:  13nMAssay Description:Binding affinity to recombinant SARS-COV2 S-RBD incubated for 5 mins by microscale thermophoresis analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50582783(CHEMBL5093610)
Affinity DataKd:  46nMAssay Description:Binding affinity to recombinant SARS-COV2 S-RBD incubated for 5 mins by microscale thermophoresis analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50582784(CHEMBL5094981)
Affinity DataKd:  2.00E+3nMAssay Description:Inhibition of SARS-COV2 spike protein mediated infection of human ACE2 expressing cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50582785(CHEMBL5070871)
Affinity DataKd:  5.00E+3nMAssay Description:Inhibition of SARS-COV2 spike protein mediated infection of human ACE2 expressing cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50582786(CHEMBL5094988)
Affinity DataKd:  2.00E+3nMAssay Description:Inhibition of SARS-COV2 spike protein mediated infection of human ACE2 expressing cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50582787(CHEMBL5088895)
Affinity DataKd:  4.00E+3nMAssay Description:Inhibition of SARS-COV2 spike protein mediated infection of human ACE2 expressing cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50582787(CHEMBL5088895)
Affinity DataKd:  0.0300nMAssay Description:Binding affinity of SARS-COV2 S-RBD by BLI assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50582786(CHEMBL5094988)
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity of SARS-COV2 S-RBD by BLI assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50582787(CHEMBL5088895)
Affinity DataKd:  2.20E+3nMAssay Description:Binding affinity to biotinylated recombinant SARS-COV2 S-RBD by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50582092(CHEMBL5091761)
Affinity DataKd: >2.50E+4nMAssay Description:Binding affinity to CM5 sensor chip immobilized SARS-CoV-2 spike glycoprotein assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50582093(CHEMBL5085757)
Affinity DataKd:  1.91E+4nMAssay Description:Binding affinity to CM5 sensor chip immobilized SARS-CoV-2 spike glycoprotein assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50582094(CHEMBL5087131)
Affinity DataKd: >2.50E+4nMAssay Description:Binding affinity to CM5 sensor chip immobilized SARS-CoV-2 spike glycoprotein assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50582095(CHEMBL5093511)
Affinity DataKd: >2.50E+4nMAssay Description:Binding affinity to CM5 sensor chip immobilized SARS-CoV-2 spike glycoprotein assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50582096(CHEMBL5092252)
Affinity DataKd: >2.50E+4nMAssay Description:Binding affinity to CM5 sensor chip immobilized SARS-CoV-2 spike glycoprotein assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50582097(CHEMBL5070941)
Affinity DataKd: >2.50E+4nMAssay Description:Binding affinity to CM5 sensor chip immobilized SARS-CoV-2 spike glycoprotein assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50582098(CHEMBL5080077)
Affinity DataKd:  3.26E+3nMAssay Description:Binding affinity to CM5 sensor chip immobilized SARS-CoV-2 spike glycoprotein assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50582099(CHEMBL5077268)
Affinity DataKd:  1.14E+4nMAssay Description:Binding affinity to CM5 sensor chip immobilized SARS-CoV-2 spike glycoprotein assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50580228(CHEMBL5085069)
Affinity DataKd:  31nMAssay Description:Binding affinity to SARS-CoV-2 spike protein receptor-binding domain by biolayer interferometry (BLI) assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50580229(CHEMBL5078219)
Affinity DataKd:  105nMAssay Description:Binding affinity to SARS-CoV-2 spike protein receptor-binding domain by biolayer interferometry (BLI) assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50580230(CHEMBL5079992)
Affinity DataKd:  29nMAssay Description:Binding affinity to SARS-CoV-2 spike protein receptor-binding domain by biolayer interferometry (BLI) assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50580315(CHEMBL5088335)
Affinity DataEC50:  5.00E+3nMAssay Description:Inhibition of SARS-CoV-2 spike glycoprotein expressed in HEK293T cells transfected with pAAV-CAG-HnCovS-RFP assessed as inhibition of membrane fusion...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50580316(CHEMBL5094996)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of SARS-CoV-2 spike glycoprotein expressed in HEK293T cells transfected with pAAV-CAG-HnCovS-RFP assessed as inhibition of membrane fusion...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50591871(CHEMBL5195094)
Affinity DataKd:  780nMAssay Description:Binding affinity to SARS-CoV-2 Spike trimer protein by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50524786(CHEMBL4467587)
Affinity DataKd:  1.39E+4nMAssay Description:Binding affinity to SARS-CoV-2 Spike trimer protein by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50595278(CHEMBL5205832)
Affinity DataKd:  6.94E+3nMAssay Description:Binding affinity to SARS-CoV-2 spike protein receptor-binding domain assessed as equilibrium dissociation constant by biolayer interferometry assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50595279(CHEMBL5187952)
Affinity DataKd:  7.29E+3nMAssay Description:Binding affinity to SARS-CoV-2 spike protein receptor-binding domain assessed as equilibrium dissociation constant by biolayer interferometry assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50157304(3',5-diallylbiphenyl-2,4'-diol | CHEMBL16901 | cid...)
Affinity DataKd:  2.50E+4nMAssay Description:Binding affinity to SARS-CoV-2 spike protein receptor-binding domain assessed as equilibrium dissociation constant by biolayer interferometry assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50596580(CHEMBL5173280)
Affinity DataKd:  9.17E+4nMAssay Description:Binding affinity to SARS-CoV-2 Spike glycoprotein receptor-binding domain at 1.875 to 50 uM by SPR assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50596581(CHEMBL5171650)
Affinity DataKd:  6.79E+4nMAssay Description:Binding affinity to SARS-CoV-2 Spike glycoprotein receptor-binding domain at 1.875 to 50 uM by SPR assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50596580(CHEMBL5173280)
Affinity DataKd:  6.47E+4nMAssay Description:Binding affinity to SARS-CoV-2 Spike glycoprotein receptor-binding domain at 1.875 to 50 uM in presence of wallichins D by SPR assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50596581(CHEMBL5171650)
Affinity DataKd:  6.47E+4nMAssay Description:Binding affinity to SARS-CoV-2 Spike glycoprotein receptor-binding domain at 1.875 to 50 uM in presence of wallichins C by SPR assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50378783(CLOFAZIMINE)
Affinity DataKd:  3.82E+3nMAssay Description:Binding affinity to SARS-CoV-2 spike protein assessed as Kd by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50604261(CHEMBL5183417)
Affinity DataKd:  2.52E+3nMAssay Description:Binding affinity to SARS-CoV-2 spike protein assessed as Kd by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50619251(CHEMBL5400898)
Affinity DataKd:  570nMAssay Description:Binding affinity to biotinylated recombinant SARS-CoV-2 spike protein RBD assessed as dissociation constant measured after 240 secs by biolayer inter...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50619251(CHEMBL5400898)
Affinity DataKd:  4.10E+3nMAssay Description:Binding affinity to his tagged recombinant SARS-CoV-2 B1.617.2 (Delta) spike protein assessed as dissociation constant measured after 240 secs by bio...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSpike glycoprotein(2019-nCoV)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM430624(NHC | EIDD-1931 | N4-Hydroxycytidine | Uridine, 4-...)
Affinity DataEC50:  300nMAssay Description:Determination of the inhibitory activity of compounds on the replication of 2019 novel coronavirus (SARS-CoV-2): anti-novel coronavirus activity test...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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