Compile Data Set for Download or QSAR
Report error Found 506 Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent betaine transporter'
LigandPNGBDBM50473314(CHEMBL553068)
Affinity DataIC50: 51nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50081891(1-[2-(3,3-Diphenyl-propoxy)-ethyl]-piperidine-3-ca...)
Affinity DataIC50: 55nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473316(CHEMBL545694)
Affinity DataIC50: 68nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473312(CHEMBL543108)
Affinity DataIC50: 74nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50080346((R)-1-(2-Benzhydrylideneaminooxy-ethyl)-piperidine...)
Affinity DataIC50: 82nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50081888((R)-1-[2-(2-Diphenylamino-ethoxy)-ethyl]-piperidin...)
Affinity DataIC50: 90nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473321(CHEMBL563076)
Affinity DataIC50: 105nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50039251(CHEMBL1027 | Gabitril | 1-[4,4-Bis-(3-methyl-4,5-d...)
Affinity DataIC50: 180nMAssay Description:Inhibition of [3H]GABA uptake at GAT2 in mouse astrocytes after 3 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50437146(CHEMBL1189315)
Affinity DataIC50: 184nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473306(CHEMBL556178)
Affinity DataIC50: 248nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473319(CHEMBL555856)
Affinity DataIC50: 265nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50437144(CHEMBL1190271)
Affinity DataIC50: 308nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50003634(1-(4,4-Diphenyl-but-3-enyl)-piperidine-3-carboxyli...)
Affinity DataIC50: 330nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50039251(CHEMBL1027 | Gabitril | 1-[4,4-Bis-(3-methyl-4,5-d...)
Affinity DataIC50: 360nMAssay Description:Inhibition of [3H]GABA uptake at GAT2 in mouse neurons after 3 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473315(CHEMBL541561)
Affinity DataIC50: 460nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473313(CHEMBL545690)
Affinity DataIC50: 561nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50101329(CHEMBL3326391)
Affinity DataIC50: 590nMAssay Description:Inhibition of human BGT1 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473311(CHEMBL543342)
Affinity DataIC50: 644nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50437145(CHEMBL1196076)
Affinity DataIC50: 647nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473317(CHEMBL553053)
Affinity DataIC50: 696nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473320(CHEMBL545452)
Affinity DataIC50: 770nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473309(CHEMBL552675)
Affinity DataIC50: 851nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473302(CHEMBL555631)
Affinity DataIC50: 1.16E+3nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473303(CHEMBL542641)
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50003653(CHEMBL542610 | 1-(2-Benzhydryloxy-ethyl)-piperidin...)
Affinity DataIC50: 1.37E+3nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50419338(CHEMBL1446457)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of mouse mGAT2 expressed in HEK293 cells assessed as inhibition of [3H]GABA uptake after 3 mins incubation by TopCount microplate scintill...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50250267(CHEMBL1882801)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of human BGT1/human GAT3 chimera D expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50250267(CHEMBL1882801)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of human BGT1/human GAT3 chimera D expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50343258(4-((4,4-bis(3-methylthiophen-2-yl)but-3-enyl)(meth...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of [3H]GABA uptake at GAT2 in mouse astrocytes after 3 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50343258(4-((4,4-bis(3-methylthiophen-2-yl)but-3-enyl)(meth...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of [3H]GABA uptake at GAT2 in mouse neurons after 3 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50226144(CHEBI:64307 | 2,4-Diamino-Butyric Acid | DL-2,4-di...)
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro inhibition of rat neuronal (synaptosomal) GABA uptake.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50078167(CHEMBL69064)
Affinity DataIC50: 2.02E+3nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473308(CHEMBL541821)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473305(CHEMBL71789)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50525188(CHEMBL4526098)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human BGT1 expressed in Flp-In CHO cells assessed as reduction in [3H]GABA uptake incubated for 3 mins by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50620816(CHEMBL5411369)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of mouse GAT2 transfected in HEK293 cells assessed as reduction in [3H]-GABA uptake preincubated for 25 mins followed by [3H]-GABA additio...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSodium- and chloride-dependent betaine transporter(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50525188(CHEMBL4526098)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of human BGT1 expressed in Flp-In CHO cells assessed as reduction in [3H]GABA uptake incubated for 3 mins by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | cid_119 | Gamma-A...)
Affinity DataIC50: 3.89E+3nMAssay Description:Inhibition of human BGT1/human GAT3 chimera D expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | cid_119 | Gamma-A...)
Affinity DataIC50: 3.89E+3nMAssay Description:Inhibition of human BGT1/human GAT3 chimera D expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50563998(CHEMBL4781266)
Affinity DataIC50: 4.47E+3nMAssay Description:Inhibition of mouse GAT2 expressed in human HEK293 cell line assessed as inhibition of [3H]GABA uptake measured after 40 mins by LC-ESI-MS/MS analysi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50577077(CHEMBL4854996)
Affinity DataIC50: 4.57E+3nMAssay Description:Inhibition of mouse GAT2 expressed in human HEK293 cell line assessed as inhibition of [3H]GABA uptake measured after 40 mins by LC-ESI-MS/MS analysi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50013223(CHEMBL349005 | Pyrrolidin-3-yl-acetic acid ((S)-(+...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human BGT1 expressed in Flp-In CHO cells assessed as reduction in [3H]GABA uptake incubated for 3 mins by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50013223(CHEMBL349005 | Pyrrolidin-3-yl-acetic acid ((S)-(+...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human BGT1 expressed in Flp-In CHO cells assessed as reduction in [3H]GABA uptake incubated for 3 mins by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50419338(CHEMBL1446457)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human BGT1 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50419338(CHEMBL1446457)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human BGT1 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50438758(CHEMBL2415009)
Affinity DataIC50: 5.48E+3nMAssay Description:Inhibition of human BGT1 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50101328(CHEMBL3040189)
Affinity DataIC50: 5.48E+3nMAssay Description:Inhibition of human BGT1 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50473318(CHEMBL539773)
Affinity DataIC50: 5.51E+3nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50577076(CHEMBL4858459)
Affinity DataIC50: 5.75E+3nMAssay Description:Inhibition of mouse GAT2 expressed in human HEK293 cell line assessed as inhibition of [3H]GABA uptake measured after 40 mins by LC-ESI-MS/MS analysi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50021385(CHEMBL3289583)
Affinity DataIC50: 5.89E+3nMAssay Description:Inhibition of mouse GAT2 expressed in HEK293 cells assessed as decrease in [3H]GABA uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 506 total ) | Next | Last >>
Jump to: