BindingDB PrimarySearch

Report error Found 35 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 1 subunit alpha/subunit beta-1'

Sodium channel protein type 1 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL

IC50: 2.30E+3nMAssay Description:Inhibition of recombinant human full length Nav1.1 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL

BDBM50530538(CHEMBL4580815)

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL

BDBM50530540(CHEMBL4458508)

IC50: 1.00E+4nMAssay Description:Inhibition of recombinant human full length Nav1.1 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL

BDBM50530537(CHEMBL4471825)

PDB
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL

BDBM50530536(CHEMBL4580996 | US11174268, Example 336)

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid PDB Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL

BDBM50530539(CHEMBL4460028 | US11174268, Example 300)

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL

BDBM50530536(CHEMBL4580996 | US11174268, Example 336)

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid PDB Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL

BDBM50530539(CHEMBL4460028 | US11174268, Example 300)

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL

BDBM50530535(CHEMBL4466858 | US11174268, Example 205)

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL

BDBM50530540(CHEMBL4458508)

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL

BDBM50530537(CHEMBL4471825)

PDB
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL

BDBM50530535(CHEMBL4466858 | US11174268, Example 205)

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1/subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL

BDBM258113(US9493448, 15 | US9845313, Example 15)

IC50: 1.30E+4nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1/subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL

BDBM258161(US9493448, 63 | BDBM301817)

IC50: 1.40E+4nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1/subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL

BDBM258162(US9493448, 64 | US9597330, Example 21 | US9845313,...)

IC50: 1.60E+4nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL

BDBM50530533(CHEMBL4435054 | US11174268, Example 185)

IC50: 2.06E+4nMAssay Description:Inhibition of recombinant human full length Nav1.1 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL

BDBM50530533(CHEMBL4435054 | US11174268, Example 185)

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1/subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL

BDBM258106(US9493448, 8 | US9845313, Example 8)

IC50: 2.60E+4nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1/subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL

BDBM258125(US9493448, 27 | US9597330, Example 4 | US9845313, ...)

IC50: 5.20E+4nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1/subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL

BDBM258103(US9493448, 5 | US9493448, 10)

IC50: 9.10E+4nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1/subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL

BDBM258141(US9493448, 43 | US9597330, Example 10 | US9845313,...)

IC50: 9.20E+4nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1/subunit beta-2(Mouse)
Daiichi Sankyo

Curated by ChEMBL

BDBM258146(US9493448, 48 | US9493448, 122 | US9493448, 154 | ...)

IC50: 1.00E+5nMAssay Description:Inhibition of mouse Nav1.1/beta1/beta2 expressed in HEK293A cells with -120 mV holding potential by whole cell manual patch clamp methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1/subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL

BDBM258102(US9493448, 4 | US9845313, Example 4)

IC50: 1.00E+5nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1/subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL

BDBM50257179(CHEMBL2325622)

IC50: 1.00E+5nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1/subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL

BDBM258146(US9493448, 48 | US9493448, 122 | US9493448, 154 | ...)

IC50: 1.00E+5nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1/subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL

BDBM258146(US9493448, 48 | US9493448, 122 | US9493448, 154 | ...)

IC50: 1.00E+5nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Purchase PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1/subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL

BDBM258118(US9493448, 20 | US9597330, Example 2 | US9845313, ...)

IC50: 1.00E+5nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1/subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL

BDBM50240267(CHEMBL2325014)

IC50: 1.00E+5nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Purchase CHEMBL PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1/subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL

BDBM258144(US9493448, 46 | US9597330, Example 11 | US9845313,...)

IC50: 1.00E+5nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1/subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL

BDBM258128(US9493448, 30 | US9845313, Example 30)

IC50: 1.00E+5nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1/subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL

BDBM50543816(CHEMBL4647897)

IC50: 1.00E+5nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1/subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL

BDBM258123(US9493448, 25 | US9597330, Example 3 | US9845313, ...)

IC50: 1.00E+5nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1/subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL

BDBM258112(US9493448, 14 | US9493448, 31 | US9597330, Example...)

IC50: 1.00E+5nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1/subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL

BDBM50543814(CHEMBL4644497)

IC50: 1.00E+5nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Details Article
PubMed

Sodium channel protein type 1 subunit alpha/subunit beta-1/subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL

BDBM50543815(CHEMBL4641238)

IC50: 1.00E+5nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid Similars

Details Article
PubMed