Report error Found 2088 Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 2'
Affinity DataEC50: 35.6nMpH: 7.2 T: 2°CAssay Description:Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataEC50: 6.60nMpH: 7.2 T: 2°CAssay Description:Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...More data for this Ligand-Target Pair
Affinity DataEC50: 9.20nMpH: 7.2 T: 2°CAssay Description:Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...More data for this Ligand-Target Pair
Affinity DataEC50: 1.30E+3nMpH: 7.2 T: 2°CAssay Description:Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...More data for this Ligand-Target Pair
Affinity DataEC50: 1.10nMpH: 7.2 T: 2°CAssay Description:Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...More data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as intracellular accumulation of [14C]alpha-methyl glucopyranosideMore data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as intracellular accumulation of [14C]alpha-methyl glucopyranosideMore data for this Ligand-Target Pair
Affinity DataEC50: 35nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as intracellular accumulation of [14C]alpha-methyl glucopyranosideMore data for this Ligand-Target Pair
Affinity DataEC50: 69nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as intracellular accumulation of [14C]alpha-methyl glucopyranosideMore data for this Ligand-Target Pair
Affinity DataEC50: 540nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as intracellular accumulation of [14C]alpha-methyl glucopyranosideMore data for this Ligand-Target Pair
Affinity DataEC50: 630nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as intracellular accumulation of [14C]alpha-methyl glucopyranosideMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+3nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as intracellular accumulation of [14C]alpha-methyl glucopyranosideMore data for this Ligand-Target Pair
Affinity DataEC50: 480nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as intracellular accumulation of [14C]alpha-methyl glucopyranosideMore data for this Ligand-Target Pair
Affinity DataEC50: 430nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as intracellular accumulation of [14C]alpha-methyl glucopyranosideMore data for this Ligand-Target Pair
Affinity DataEC50: 970nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as intracellular accumulation of [14C]alpha-methyl glucopyranosideMore data for this Ligand-Target Pair
Affinity DataEC50: 710nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as intracellular accumulation of [14C]alpha-methyl glucopyranosideMore data for this Ligand-Target Pair
Affinity DataEC50: 290nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as intracellular accumulation of [14C]alpha-methyl glucopyranosideMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+3nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as intracellular accumulation of [14C]alpha-methyl glucopyranosideMore data for this Ligand-Target Pair
Affinity DataEC50: 623nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as intracellular accumulation of [14C]alpha-methyl glucopyranosideMore data for this Ligand-Target Pair
Affinity DataEC50: 190nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as intracellular accumulation of [14C]alpha-methyl glucopyranosideMore data for this Ligand-Target Pair
Affinity DataEC50: 510nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as intracellular accumulation of [14C]alpha-methyl glucopyranosideMore data for this Ligand-Target Pair
Affinity DataEC50: 160nMAssay Description:Inhibition of human SGLT2 expressed in Xenopus oocyte assessed as [14C]alpha-methyl glucopyranoside uptakeMore data for this Ligand-Target Pair
Affinity DataEC50: 50nMAssay Description:Inhibition of human SGLT2 expressed in Xenopus oocyte assessed as [14C]alpha-methyl glucopyranoside uptakeMore data for this Ligand-Target Pair
Affinity DataEC50: 123nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 203nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 485nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 586nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 286nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 716nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 315nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 515nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 151nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 598nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 3.44E+3nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 588nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 118nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 39nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 249nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 284nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 2.09E+3nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 499nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 387nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 2.59E+3nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 2.37E+3nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 552nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 649nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 151nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 160nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
