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Report error Found 178 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PAK 2'
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31094(PKC-412 | cid_24202429)
Affinity DataKd:  3.30E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31096(CHEMBL290084 | Staurosporine | cid_451705 | US2024...)
Affinity DataKd:  3.10nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM13534(VX680 | N-[4-[[4-(4-methylpiperazino)-6-[(5-methyl...)
Affinity DataKd:  5.70E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  43nMAssay Description:Binding affinity to PAK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd:  2.10E+3nMAssay Description:Binding affinity to PAK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataKd:  3.30E+3nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  3.10nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd:  3.30E+3nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  43nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd:  3.30E+3nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  3.10nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50112348(CHEMBL3609372)
Affinity DataKd:  400nMAssay Description:Binding affinity to PAK2 (unknown origin) expressed in HEK293 cells after 1 hr by qPCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50112352(CHEMBL3609371)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to PAK2 (unknown origin) expressed in HEK293 cells after 1 hr by qPCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50112350(CHEMBL3609370)
Affinity DataKd: >4.00E+4nMAssay Description:Binding affinity to PAK2 (unknown origin) expressed in HEK293 cells after 1 hr by qPCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50112351(CHEMBL3609330)
Affinity DataKd: >4.00E+4nMAssay Description:Binding affinity to PAK2 (unknown origin) expressed in HEK293 cells after 1 hr by qPCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50273571(Hesperadin | TCMDC-135395 | N-(2-oxo-3-(phenyl(4-(...)
Affinity DataKd:  1.40E+4nMAssay Description:Binding affinity to human PAK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM13535(N-(4-isopropoxyphenyl)-4-[6-methoxy-7-(3-piperidin...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to PAK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to PAK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50326054(CHEMBL1240703)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to PAK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to PAK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50300690(CHEMBL576982 | N-(5-tert-Butyl-isoxazol-3-yl)-N'-{...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to PAK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM36409(CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...)
Affinity DataKd:  3.20E+3nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM12621(2,4-Diamino-5-ketopyrimidine 39 | 5-[(2,3-difluoro...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM4779(cid_156414 | PD0183805 | CHEMBL545315 | CHEMBL3196...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM6568(PD-173955 | CHEMBL386051 | 6-(2,6-dichlorophenyl)-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM4851(cid_151194 | PTK787 | CHEMBL101253 | N-(4-chloroph...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31088(1-methyl-5-[[2-[5-(trifluoromethyl)-1H-imidazol-2-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM26474(GW-786034 | JMC514632 Compound 13 | 5-({4-[(2,3-di...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM25117(AG-013736 | N-methyl-2-({3-[(E)-2-(pyridin-2-yl)et...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM25617(N-[3-({5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl}carb...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM13533(1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-m...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM25919(N-(2-aminoethyl)-3,12-dimethyl-2,5,8-triazatricycl...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM482158(TAE684 | BDBM50242742)
Affinity DataKd:  5.80E+3nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM32362(cid_11617559 | GW-2580 | 5-[[3-methoxy-4-[(4-metho...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50355494(CHEMBL1908396)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM25028(4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpipera...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50331096(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxy-7...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM60589(6-{[6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM17055((9S)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydr...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM60665(US9145414, R406 | US9212178, R406 | BDBM50249542)
Affinity DataKd:  340nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50355497(AZD-6244 | CHEMBL1614701)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM25118(4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM15138(Biochemistry 469551 Compound 11 | 5-indazolyl pyri...)
Affinity DataKd:  1.50E+3nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50161957(CHEMBL180022 | N-(4-(3-chloro-4-(pyridin-2-ylmetho...)
Affinity DataKd:  79nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50242737((R,Z)-5-(2,6-dichlorobenzylsulfonyl)-3-((3,5-dimet...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM25013(4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S...)
Affinity DataKd:  270nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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