Compile Data Set for Download or QSAR
Report error Found 92 Enz. Inhib. hit(s) with Target = 'Ribonuclease pancreatic'
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50391853(CHEMBL2147156)
Affinity DataKd:  3.10E+3nMAssay Description:Inhibition of bovine RNase A interaction to ribonuclease inhibitor protein after 30 mins by competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM22984(Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of bovine pancreas RNase A assessed as undigested supercoiled pBR322 DNA concentrationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Human)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50375418(CHEMBL408119)
Affinity DataIC50: 1.67E+5nMAssay Description:Inhibition of RNase A by precipitation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Human)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50375420(CHEMBL266234)
Affinity DataIC50: 1.97E+5nMAssay Description:Inhibition of RNase A by precipitation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50242374(topostatin | CHEMBL505529)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of bovine pancreas RNase A assessed as undigested supercoiled pBR322 DNA concentrationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50008923(4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaz...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of bovine pancreas RNase A assessed as undigested supercoiled pBR322 DNA concentrationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Human)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50233301(cytidine-3'-monophosphate | CHEMBL258728)
Affinity DataIC50: 3.12E+5nMAssay Description:Inhibition of RNase A by precipitation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Human)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50375419(CHEMBL259808)
Affinity DataIC50: 3.41E+5nMAssay Description:Inhibition of RNase A by precipitation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50164888(6-Hydroxy-3-[1-(4-hydroxy-phenyl)-meth-(E)-ylidene...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of bovine pancreas RNase A assessed as undigested supercoiled pBR322 DNA concentrationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50342010(5'-phospho-2'-deoxyuridine-3'-pyrophosphate(P'->5'...)
Affinity DataKi:  27nMpH: 5.9Assay Description:Inhibition of bovine pancreatic RNase A at pH 5.9 by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Human)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50402338(CHEMBL401150)
Affinity DataKi:  27nMAssay Description:Inhibition of RNase AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Human)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50292713(5'-phospho-2'-deoxyuridine 3-pyrophosphate (P'->5'...)
Affinity DataKi:  27nMAssay Description:Inhibition of RNase AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50292721([({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydr...)
Affinity DataKi:  41nMAssay Description:Inhibition of bovine pancreatic RNase A by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50402337(CHEMBL2206660)
Affinity DataKi:  240nMAssay Description:Inhibition of bovine pancreatic RNase AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50292724(arabinouridine 3'-phosphate | URACIL ARABINOSE-3'-...)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of bovine pancreatic RNase A by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50298711(CYTIDINE-2'-MONOPHOSPHATE | (2R,3R,4R,5R)-2-(4-ami...)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of bovine pancreatic RNase A by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50298711(CYTIDINE-2'-MONOPHOSPHATE | (2R,3R,4R,5R)-2-(4-ami...)
Affinity DataKi:  7.00E+3nMAssay Description:Competitive inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50292723(PHOSPHORIC ACID MONO-[2-(2,4-DIOXO-3,4-DIHYDRO-2H-...)
Affinity DataKi:  7.10E+3nMAssay Description:Inhibition of bovine pancreatic RNase A by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50292723(PHOSPHORIC ACID MONO-[2-(2,4-DIOXO-3,4-DIHYDRO-2H-...)
Affinity DataKi:  1.16E+4nMpH: 6.0Assay Description:Inhibition of bovine pancreatic ribonuclease A assessed as enzyme activity by spectrophotometric method pH 6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50590733(CHEMBL5174041)
Affinity DataKi:  1.20E+4nMAssay Description:Competitive inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRibonuclease pancreatic(Human)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50375418(CHEMBL408119)
Affinity DataKi:  1.32E+4nMAssay Description:Activity at RNase AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50233301(cytidine-3'-monophosphate | CHEMBL258728)
Affinity DataKi:  2.01E+4nMpH: 6.0Assay Description:Inhibition of bovine pancreatic ribonuclease A assessed as enzyme activity by spectrophotometric method pH 6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50162334(5-[3-carboxy-4-(3-nitrophenylcarboxamido)benzyl]-2...)
Affinity DataKi:  2.10E+4nMAssay Description:Inhibition of bovine pancreatic RNase A assessed as reduction in CpG cleavage by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50438455(CHEMBL2414522)
Affinity DataKi:  2.50E+4nMAssay Description:Reversible competitive inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50590732(CHEMBL5195359)
Affinity DataKi:  2.80E+4nMAssay Description:Competitive inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50590723(CHEMBL5174669)
Affinity DataKi:  2.90E+4nMAssay Description:Inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50590730(CHEMBL5179731)
Affinity DataKi:  3.20E+4nMAssay Description:Competitive inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50590725(CHEMBL5170654)
Affinity DataKi:  3.20E+4nMAssay Description:Inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50331790(3-Amino-N-[2-hydroxymethyl-5-(5-methyl-2,4-dioxo-3...)
Affinity DataKi:  3.70E+4nMAssay Description:Competitive inhibition of bovine pancreatic RNase A ribonucleolytic activity of by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50438453(CHEMBL2414524)
Affinity DataKi:  3.90E+4nMAssay Description:Reversible competitive inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Human)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50375420(CHEMBL266234)
Affinity DataKi:  4.20E+4nMAssay Description:Activity at RNase AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50590731(CHEMBL5205517)
Affinity DataKi:  4.40E+4nMAssay Description:Competitive inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM173610(9-[3'-[4-[(Uracil-1-yl)methyl]-1,2,3-triazol-1...)
Affinity DataKi:  5.55E+4nM ΔG°:  -24.7kJ/moleT: 2°CAssay Description:The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50590729(CHEMBL5179790)
Affinity DataKi:  6.00E+4nMAssay Description:Competitive inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50342006(5'-Deoxy-5'-N-(4-carboxypiperidinyl)uridine | CHEM...)
Affinity DataKi:  6.10E+4nMAssay Description:Inhibition of bovine pancreatic RNase A using 2',3'-cCMP as a substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50590724(CHEMBL5202511)
Affinity DataKi:  6.67E+4nMAssay Description:Inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50331791((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydr...)
Affinity DataKi:  6.70E+4nMAssay Description:Competitive inhibition of bovine pancreatic RNase A ribonucleolytic activity of by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM173614(9-[3'-[4-[(Thymine-1-yl)methyl]-1,2,3-triazol-...)
Affinity DataKi:  6.88E+4nM ΔG°:  -24.2kJ/moleT: 2°CAssay Description:The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50342006(5'-Deoxy-5'-N-(4-carboxypiperidinyl)uridine | CHEM...)
Affinity DataKi:  7.50E+4nMAssay Description:Inhibition of bovine pancreatic RNase A using 2',3'-cCMP as a substrate by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50292715(5'-deoxy-5'-N-(ethyl isonipecotatyl)uridine | CHEM...)
Affinity DataKi:  7.70E+4nMAssay Description:Inhibition of bovine pancreatic RNase A by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50292722(3'-uridylic acid | 3'-UMP | CHEMBL460741)
Affinity DataKi:  7.85E+4nMpH: 6.0Assay Description:Inhibition of bovine pancreatic ribonuclease A assessed as enzyme activity by spectrophotometric method pH 6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50590728(CHEMBL5198110)
Affinity DataKi:  7.90E+4nMAssay Description:Competitive inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRibonuclease pancreatic(Human)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM111444(Ser-aT (Compound 2))
Affinity DataKi:  8.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50298713(2',3'-Dideoxy-3'-L-serinylamino thymidine | CHEMBL...)
Affinity DataKi:  8.00E+4nMAssay Description:Inhibition of bovine pancreatic RNase A by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50292722(3'-uridylic acid | 3'-UMP | CHEMBL460741)
Affinity DataKi:  8.20E+4nMAssay Description:Inhibition of bovine pancreatic RNase A by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50438456(CHEMBL2414521)
Affinity DataKi:  8.80E+4nMAssay Description:Reversible competitive inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50438454(CHEMBL2414523)
Affinity DataKi:  9.30E+4nMAssay Description:Reversible competitive inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50438451(CHEMBL2414510)
Affinity DataKi:  9.50E+4nMAssay Description:Reversible competitive inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Human)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50375419(CHEMBL259808)
Affinity DataKi:  9.50E+4nMAssay Description:Activity at RNase AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM173612(9-[3'-[4-[(Cytosine-1-yl)methyl]-1,2,3-triazol...)
Affinity DataKi:  9.85E+4nM ΔG°:  -23.3kJ/moleT: 2°CAssay Description:The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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