Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with Target = 'Retinoic acid receptor RXR-alpha/RXR-beta/RXR-gamma' Sort by
TargetRetinoic acid receptor RXR-alpha/RXR-beta/RXR-gamma(Human)
Arizona State University

Curated by ChEMBL
LigandPNGBDBM50533807(CHEMBL4440825)
Affinity DataEC50:  296nMAssay Description:Agonist activity at human RXR binding domain and activation domain expressed in human HCT116 cells assessed as rexinoid activity incubated for 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha/RXR-beta/RXR-gamma(Human)
Arizona State University

Curated by ChEMBL
LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataEC50:  52nMAssay Description:Agonist activity at human RXR binding domain and activation domain expressed in human HCT116 cells assessed as rexinoid activity incubated for 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha/RXR-beta/RXR-gamma(Human)
Arizona State University

Curated by ChEMBL
LigandPNGBDBM50533814(CHEMBL4459731)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human RXR binding domain and activation domain expressed in human HCT116 cells assessed as rexinoid activity incubated for 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha/RXR-beta/RXR-gamma(Human)
Arizona State University

Curated by ChEMBL
LigandPNGBDBM50533813(CHEMBL4476213)
Affinity DataEC50:  34nMAssay Description:Agonist activity at human RXR binding domain and activation domain expressed in human HCT116 cells assessed as rexinoid activity incubated for 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha/RXR-beta/RXR-gamma(Human)
Arizona State University

Curated by ChEMBL
LigandPNGBDBM50533812(CHEMBL4545837)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human RXR binding domain and activation domain expressed in human HCT116 cells assessed as rexinoid activity incubated for 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha/RXR-beta/RXR-gamma(Human)
Arizona State University

Curated by ChEMBL
LigandPNGBDBM50533811(CHEMBL4475014)
Affinity DataEC50:  143nMAssay Description:Agonist activity at human RXR binding domain and activation domain expressed in human HCT116 cells assessed as rexinoid activity incubated for 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha/RXR-beta/RXR-gamma(Human)
Arizona State University

Curated by ChEMBL
LigandPNGBDBM50533810(CHEMBL4560758)
Affinity DataEC50:  126nMAssay Description:Agonist activity at human RXR binding domain and activation domain expressed in human HCT116 cells assessed as rexinoid activity incubated for 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha/RXR-beta/RXR-gamma(Human)
Arizona State University

Curated by ChEMBL
LigandPNGBDBM50324896(6-[N-Ethyl(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-...)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human RXR binding domain and activation domain expressed in human HCT116 cells assessed as rexinoid activity incubated for 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha/RXR-beta/RXR-gamma(Human)
Arizona State University

Curated by ChEMBL
LigandPNGBDBM50533809(CHEMBL4547228)
Affinity DataEC50:  7.90nMAssay Description:Agonist activity at human RXR binding domain and activation domain expressed in human HCT116 cells assessed as rexinoid activity incubated for 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha/RXR-beta/RXR-gamma(Human)
Arizona State University

Curated by ChEMBL
LigandPNGBDBM50533808(CHEMBL4468317)
Affinity DataEC50:  364nMAssay Description:Agonist activity at human RXR binding domain and activation domain expressed in human HCT116 cells assessed as rexinoid activity incubated for 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha/RXR-beta/RXR-gamma(Human)
Arizona State University

Curated by ChEMBL
LigandPNGBDBM50533806(CHEMBL4476114)
Affinity DataEC50:  1.82E+4nMAssay Description:Agonist activity at human RXR binding domain and activation domain expressed in human HCT116 cells assessed as rexinoid activity incubated for 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha/RXR-beta/RXR-gamma(Human)
Arizona State University

Curated by ChEMBL
LigandPNGBDBM50533805(CHEMBL4441103)
Affinity DataEC50: >8.00E+4nMAssay Description:Agonist activity at human RXR binding domain and activation domain expressed in human HCT116 cells assessed as rexinoid activity incubated for 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha/RXR-beta/RXR-gamma(Human)
Arizona State University

Curated by ChEMBL
LigandPNGBDBM50533804(CHEMBL4574155)
Affinity DataEC50:  41nMAssay Description:Agonist activity at human RXR binding domain and activation domain expressed in human HCT116 cells assessed as rexinoid activity incubated for 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha/RXR-beta/RXR-gamma(Human)
Arizona State University

Curated by ChEMBL
LigandPNGBDBM50537147(CHEMBL4537625)
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of GAL4-fused human RXR transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha/RXR-beta/RXR-gamma(Human)
Arizona State University

Curated by ChEMBL
LigandPNGBDBM50490452(CHEMBL2321917)
Affinity DataEC50:  0.140nMAssay Description:Agonist activity at RXR (unknown origin) in presence of RAR agonist Am80More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha/RXR-beta/RXR-gamma(Human)
Arizona State University

Curated by ChEMBL
LigandPNGBDBM50490451(CHEMBL2325917)
Affinity DataEC50:  0.130nMAssay Description:Agonist activity at RXR (unknown origin) in presence of RAR agonist Am80More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha/RXR-beta/RXR-gamma(Human)
Arizona State University

Curated by ChEMBL
LigandPNGBDBM28802(2-{[(5-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-...)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at human RXR by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2017
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha/RXR-beta/RXR-gamma(Human)
Arizona State University

Curated by ChEMBL
LigandPNGBDBM50177015(CHEMBL3814206 | US10144715, Compound 19-1)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha/RXR-beta/RXR-gamma(Human)
Arizona State University

Curated by ChEMBL
LigandPNGBDBM50508127(CHEMBL4449687)
Affinity DataIC50: 2.44E+4nMAssay Description:Antagonist activity at retinoid X receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed