Compile Data Set for Download or QSAR
Report error Found 63 Enz. Inhib. hit(s) with Target = 'Replicative DNA helicase'
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295892((Z)-5-(4-hydroxy-3,5-dimethoxybenzylidene)-3-(4-ni...)
Affinity DataIC50: 700nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Bacillus anthracis)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50400427(CHEMBL2178445)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Bacillus anthracis)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50400420(CHEMBL2178452)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Bacillus anthracis)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50400418(CHEMBL2178454)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Bacillus anthracis)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50400416(CHEMBL2178456)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295893((Z)-3-(4-chlorophenyl)-5-(4-hydroxy-3,5-dimethoxyb...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Bacillus anthracis)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50400424(CHEMBL2178448)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Bacillus anthracis)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50400429(CHEMBL2178443)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295894((Z)-3-(3-chlorophenyl)-5-(4-hydroxy-3,5-dimethoxyb...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Bacillus anthracis)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50400428(CHEMBL2178444)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295891((Z)-5-(4-hydroxy-3,5-dimethoxybenzylidene)-2-thiox...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM11985(4-(2,5-dimethyl-1H-pyrrol-1-yl)-2-hydroxybenzoic a...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM11994(2-{[4-(2,5-dimethyl-1H-pyrrol-1-yl)phenyl]sulfanyl...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Targanta Therapeutics

Curated by ChEMBL
LigandPNGBDBM50179004(N2,N4-bis(3,4-difluorophenyl)-6-(4-(2-phenoxyethyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa DnaB helicaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Bacillus anthracis)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50400415(CHEMBL2178457)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Targanta Therapeutics

Curated by ChEMBL
LigandPNGBDBM50179001(N2,N4-bis(3,4-difluorophenyl)-6-(4-isobutylpiperaz...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa DnaB helicaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Targanta Therapeutics

Curated by ChEMBL
LigandPNGBDBM50179000(N2-(4-chlorophenyl)-N4-(2-morpholinoethyl)-N6-(4-n...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa DnaB helicaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Bacillus anthracis)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50400426(CHEMBL2178446)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Targanta Therapeutics

Curated by ChEMBL
LigandPNGBDBM50179007(6-(4-benzylpiperazin-1-yl)-N2,N4-bis(3,4-difluorop...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa DnaB helicaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Targanta Therapeutics

Curated by ChEMBL
LigandPNGBDBM50178998(1-(4-(4,6-bis(4-bromophenylamino)-1,3,5-triazin-2-...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa DnaB helicaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Bacillus anthracis)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50400425(CHEMBL2178447)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Bacillus anthracis)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50400435(CHEMBL2177806)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Bacillus anthracis)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50400431(CHEMBL2177810)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Bacillus anthracis)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50400440(CHEMBL2177801)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Bacillus anthracis)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50400419(CHEMBL2178453)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Bacillus anthracis)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50400423(CHEMBL2178449)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Bacillus anthracis)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50400430(CHEMBL2177811)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Bacillus anthracis)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50400434(CHEMBL2177807)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295886(4-(2-methylthiazol-4-yl)-1H-pyrrole-2-carboxylic a...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295897(6,7-dihydroxy-4-((1-methyl-1H-benzo[d]imidazol-2-y...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295898(4-((4-amino-5-(2-fluorobenzyl)-4H-1,2,4-triazol-3-...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Bacillus anthracis)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50400432(CHEMBL2177809)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295895(3,4,5-trimethoxy-N-(6-(morpholinosulfonyl)benzo[d]...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Targanta Therapeutics

Curated by ChEMBL
LigandPNGBDBM50178999(2-(4-(4,6-bis(3,4-difluorophenylamino)-1,3,5-triaz...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa DnaB helicaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Targanta Therapeutics

Curated by ChEMBL
LigandPNGBDBM50178996(N2,N4-bis(3,4-difluorophenyl)-N6-(2-morpholinoethy...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa DnaB helicaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Bacillus anthracis)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50400433(CHEMBL2177808)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Targanta Therapeutics

Curated by ChEMBL
LigandPNGBDBM50179002(N2,N4-bis(4-chlorophenyl)-N6-(2-morpholinoethyl)-1...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa DnaB helicaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Bacillus anthracis)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50400417(CHEMBL2178455)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295889(6-(benzofuran-2-yl)-N2-(4-methoxyphenyl)-1,3,5-tri...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Targanta Therapeutics

Curated by ChEMBL
LigandPNGBDBM50179005(N2,N4-bis(4-fluorophenyl)-6-(4-methylpiperazin-1-y...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa DnaB helicaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Targanta Therapeutics

Curated by ChEMBL
LigandPNGBDBM50178994(2-(4-(4,6-bis(4-fluorophenylamino)-1,3,5-triazin-2...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa DnaB helicaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Targanta Therapeutics

Curated by ChEMBL
LigandPNGBDBM50178995(N2,N4,N6-tris(3-chlorophenyl)-1,3,5-triazine-2,4,6...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa DnaB helicaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM34851(MLS000693314 | 3-benzyl-7,8-dihydroxy-4-methylchro...)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295890(N-(4-(N-(3,4-dimethylisoxazol-5-yl)sulfamoyl)pheny...)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295896(2-ethoxy-N-(6-sulfamoylbenzo[d]thiazol-2-yl)benzam...)
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Bacillus anthracis)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50400439(CHEMBL2177802)
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295899(3-(4,8-dimethyl-7-(naphthalen-1-ylmethoxy)-2-oxo-2...)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Targanta Therapeutics

Curated by ChEMBL
LigandPNGBDBM50179006(N2-(4-chlorophenyl)-N4-(2-morpholinoethyl)-N6-phen...)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa DnaB helicaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Bacillus anthracis)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50400442(CHEMBL2178460)
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicative DNA helicase(Bacillus anthracis)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50400422(CHEMBL2178450)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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