Compile Data Set for Download or QSAR
Report error Found 65 Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase [1-324]'
LigandPNGBDBM202665(US9694016, 10 | US9242969, 10 | US10245267, Exampl...)
Affinity DataIC50: 0.118nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202665(US9694016, 10 | US9242969, 10 | US10245267, Exampl...)
Affinity DataIC50: 0.118nMpH: 7.5 T: 2°CAssay Description:Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202665(US9694016, 10 | US9242969, 10 | US10245267, Exampl...)
Affinity DataIC50: 0.120nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202697(US9242969, 43 | US10245267, Example 42 | US1070971...)
Affinity DataIC50: 0.137nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202696(US9694016, 42 | US9242969, 42 | US10245267, Exampl...)
Affinity DataIC50: 0.137nMpH: 7.5 T: 2°CAssay Description:Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202656(US9694016, 1 | US9242969, 1 | US10245267, Example ...)
Affinity DataIC50: 0.140nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202696(US9694016, 42 | US9242969, 42 | US10245267, Exampl...)
Affinity DataIC50: 0.140nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202656(US9694016, 1 | US9242969, 1 | US10245267, Example ...)
Affinity DataIC50: 0.144nMpH: 7.5 T: 2°CAssay Description:Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202656(US9694016, 1 | US9242969, 1 | US10245267, Example ...)
Affinity DataIC50: 0.144nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202772(US9694016, 119 | US9242969, 119 | US10245267, Exam...)
Affinity DataIC50: 0.270nMpH: 7.5 T: 2°CAssay Description:Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202772(US9694016, 119 | US9242969, 119 | US10245267, Exam...)
Affinity DataIC50: 0.270nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202772(US9694016, 119 | US9242969, 119 | US10245267, Exam...)
Affinity DataIC50: 0.270nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202771(US9694016, 118 | US9242969, 118 | US10245267, Exam...)
Affinity DataIC50: 0.308nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202771(US9694016, 118 | US9242969, 118 | US10245267, Exam...)
Affinity DataIC50: 0.308nMpH: 7.5 T: 2°CAssay Description:Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202771(US9694016, 118 | US9242969, 118 | US10245267, Exam...)
Affinity DataIC50: 0.310nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202697(US9242969, 43 | US10245267, Example 42 | US1070971...)
Affinity DataIC50: 0.376nMpH: 7.5 T: 2°CAssay Description:Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202696(US9694016, 42 | US9242969, 42 | US10245267, Exampl...)
Affinity DataIC50: 0.376nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202718(US9694016, 111 | US9242969, 64 | US10245267, Examp...)
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202718(US9694016, 111 | US9242969, 64 | US10245267, Examp...)
Affinity DataIC50: 0.403nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202764(US9694016, 64 | US9242969, 111 | US10245267, Examp...)
Affinity DataIC50: 0.403nMpH: 7.5 T: 2°CAssay Description:Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202661(US9694016, 6 | US9242969, 6 | US10245267, Example ...)
Affinity DataIC50: 0.408nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202661(US9694016, 6 | US9242969, 6 | US10245267, Example ...)
Affinity DataIC50: 0.408nMpH: 7.5 T: 2°CAssay Description:Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202661(US9694016, 6 | US9242969, 6 | US10245267, Example ...)
Affinity DataIC50: 0.410nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202845(US9694016, 198 | US9242969, 198 | US10245267, Exam...)
Affinity DataIC50: 0.455nMpH: 7.5 T: 2°CAssay Description:Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202845(US9694016, 198 | US9242969, 198 | US10245267, Exam...)
Affinity DataIC50: 0.455nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202845(US9694016, 198 | US9242969, 198 | US10245267, Exam...)
Affinity DataIC50: 0.460nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202717(US9694016, 63 | US9242969, 63 | US10245267, Exampl...)
Affinity DataIC50: 0.508nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202717(US9694016, 63 | US9242969, 63 | US10245267, Exampl...)
Affinity DataIC50: 0.508nMpH: 7.5 T: 2°CAssay Description:Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202663(US9694016, 8 | US9242969, 9 | US9242969, 8 | US107...)
Affinity DataIC50: 0.510nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202717(US9694016, 63 | US9242969, 63 | US10245267, Exampl...)
Affinity DataIC50: 0.510nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM77059(US9694016, 9 | US10245267, Example 9 | US10709712,...)
Affinity DataIC50: 0.514nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202663(US9694016, 8 | US9242969, 9 | US9242969, 8 | US107...)
Affinity DataIC50: 0.514nMpH: 7.5 T: 2°CAssay Description:Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202668(US9694016, 13 | US9242969, 13 | US10245267, Exampl...)
Affinity DataIC50: 0.530nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202668(US9694016, 13 | US9242969, 13 | US10245267, Exampl...)
Affinity DataIC50: 0.533nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202668(US9694016, 13 | US9242969, 13 | US10245267, Exampl...)
Affinity DataIC50: 0.533nMpH: 7.5 T: 2°CAssay Description:Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202666(US9694016, 11 | US9242969, 11 | US10245267, Exampl...)
Affinity DataIC50: 0.580nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202666(US9694016, 11 | US9242969, 11 | US10245267, Exampl...)
Affinity DataIC50: 0.580nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202666(US9694016, 11 | US9242969, 11 | US10245267, Exampl...)
Affinity DataIC50: 0.580nMpH: 7.5 T: 2°CAssay Description:Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202843(US9694016, 196 | US9242969, 196 | US10245267, Exam...)
Affinity DataIC50: 0.620nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202843(US9694016, 196 | US9242969, 196 | US10245267, Exam...)
Affinity DataIC50: 0.621nMpH: 7.5 T: 2°CAssay Description:Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202843(US9694016, 196 | US9242969, 196 | US10245267, Exam...)
Affinity DataIC50: 0.621nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202698(US9694016, 44 | US9242969, 44 | US10245267, Exampl...)
Affinity DataIC50: 0.710nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202698(US9694016, 44 | US9242969, 44 | US10245267, Exampl...)
Affinity DataIC50: 0.714nMpH: 7.5 T: 2°CAssay Description:Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202698(US9694016, 44 | US9242969, 44 | US10245267, Exampl...)
Affinity DataIC50: 0.714nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202669(US9694016, 14 | US9242969, 14 | US10245267, Exampl...)
Affinity DataIC50: 0.800nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202669(US9694016, 14 | US9242969, 14 | US10245267, Exampl...)
Affinity DataIC50: 0.803nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202669(US9694016, 14 | US9242969, 14 | US10245267, Exampl...)
Affinity DataIC50: 0.803nMpH: 7.5 T: 2°CAssay Description:Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202718(US9694016, 111 | US9242969, 64 | US10245267, Examp...)
Affinity DataIC50: 0.847nMpH: 7.5 T: 2°CAssay Description:Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202764(US9694016, 64 | US9242969, 111 | US10245267, Examp...)
Affinity DataIC50: 0.847nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM202764(US9694016, 64 | US9242969, 111 | US10245267, Examp...)
Affinity DataIC50: 0.850nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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