Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with Target = 'Putative heat shock protein HSP 90-alpha A4'
TargetPutative heat shock protein HSP 90-alpha A4(Human)
Shandong University

LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50: 140nMpH: 7.3Assay Description:Briefly, reaction mixes (100 µL) containing 20 mM HEPES (pH 7.3), 50 mM KCl, 2 mM DTT, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% Triton X-100 with 0.1 mg/mL B...More data for this Ligand-Target Pair
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TargetPutative heat shock protein HSP 90-alpha A4(Human)
Shandong University

LigandPNGBDBM50008057(CHEBI:64153 | BMS-722782 | TANESPIMYCIN)
Affinity DataIC50: 780nMpH: 7.3Assay Description:Briefly, reaction mixes (100 µL) containing 20 mM HEPES (pH 7.3), 50 mM KCl, 2 mM DTT, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% Triton X-100 with 0.1 mg/mL B...More data for this Ligand-Target Pair
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TargetPutative heat shock protein HSP 90-alpha A4(Human)
Shandong University

LigandPNGBDBM166675(3-(5-chloro-2,4-dihydroxyphenyl)-5,6-dihydro-4H-be...)
Affinity DataIC50: 800nMAssay Description:The fluorescence polarization (FP) assay was performed as described in the reference (Bioorg Med Chem. 2010. 18:6031-6043).More data for this Ligand-Target Pair
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PubMed
TargetPutative heat shock protein HSP 90-alpha A4(Human)
Shandong University

LigandPNGBDBM166670(17-AAG)
Affinity DataIC50: 1.09E+3nMAssay Description:The fluorescence polarization (FP) assay was performed as described in the reference (Bioorg Med Chem. 2010. 18:6031-6043).More data for this Ligand-Target Pair
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PubMed
TargetPutative heat shock protein HSP 90-alpha A4(Human)
Shandong University

LigandPNGBDBM166672(3-(5-chloro-2,4-dihydroxyphenyl)-5,6-dihydroisoxaz...)
Affinity DataIC50: 1.60E+3nMAssay Description:The fluorescence polarization (FP) assay was performed as described in the reference (Bioorg Med Chem. 2010. 18:6031-6043).More data for this Ligand-Target Pair
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PubMed
TargetPutative heat shock protein HSP 90-alpha A4(Human)
Shandong University

LigandPNGBDBM152737(17-(3-trifluoromethylphenylamino)-17-demethoxygeld...)
Affinity DataIC50: 2.29E+3nMpH: 7.3Assay Description:Briefly, reaction mixes (100 µL) containing 20 mM HEPES (pH 7.3), 50 mM KCl, 2 mM DTT, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% Triton X-100 with 0.1 mg/mL B...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPutative heat shock protein HSP 90-alpha A4(Human)
Shandong University

LigandPNGBDBM166673(3-(5-chloro-2,4-dihydroxyphenyl)-5,6-dihydrobenzo[...)
Affinity DataIC50: 4.80E+3nMAssay Description:The fluorescence polarization (FP) assay was performed as described in the reference (Bioorg Med Chem. 2010. 18:6031-6043).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPutative heat shock protein HSP 90-alpha A4(Human)
Shandong University

LigandPNGBDBM166676(3-(5-chloro-2,4-dihydroxyphenyl)-5,6-dihydro-4H-be...)
Affinity DataIC50: 6.30E+3nMAssay Description:The fluorescence polarization (FP) assay was performed as described in the reference (Bioorg Med Chem. 2010. 18:6031-6043).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPutative heat shock protein HSP 90-alpha A4(Human)
Shandong University

LigandPNGBDBM166671(3-(5-chloro-2,4-dihydroxyphenyl)-5,6-dihydro-6-met...)
Affinity DataIC50: 1.00E+4nMAssay Description:The fluorescence polarization (FP) assay was performed as described in the reference (Bioorg Med Chem. 2010. 18:6031-6043).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPutative heat shock protein HSP 90-alpha A4(Human)
Shandong University

LigandPNGBDBM166674(3-(5-chloro-2,4-dihydroxyphenyl)-4,5,6,7-tetrahydr...)
Affinity DataIC50: 2.60E+4nMAssay Description:The fluorescence polarization (FP) assay was performed as described in the reference (Bioorg Med Chem. 2010. 18:6031-6043).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPutative heat shock protein HSP 90-alpha A4(Human)
Shandong University

LigandPNGBDBM166677(4-(7-Oxo-4,5,6,7-tetrahydrobenzo[d]isoxazol-3-yl)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:The fluorescence polarization (FP) assay was performed as described in the reference (Bioorg Med Chem. 2010. 18:6031-6043).More data for this Ligand-Target Pair
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PubMed
TargetPutative heat shock protein HSP 90-alpha A4(Human)
Shandong University

LigandPNGBDBM166678(4-(7-Hydroxyimino-4,5,6,7-tetrahydro-benzo[d]isoxa...)
Affinity DataIC50: 1.00E+5nMAssay Description:The fluorescence polarization (FP) assay was performed as described in the reference (Bioorg Med Chem. 2010. 18:6031-6043).More data for this Ligand-Target Pair
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PubMed
TargetPutative heat shock protein HSP 90-alpha A4(Human)
Shandong University

LigandPNGBDBM166679(4-(7-(2-Morpholin-4-yl-ethoxyimino)-4,5,6,7-tetrah...)
Affinity DataIC50: 1.00E+5nMAssay Description:The fluorescence polarization (FP) assay was performed as described in the reference (Bioorg Med Chem. 2010. 18:6031-6043).More data for this Ligand-Target Pair
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PubMed
TargetPutative heat shock protein HSP 90-alpha A4(Human)
Shandong University

LigandPNGBDBM166680(4-(7-(2-Aminoethoxyimino)-4,5,6,7-tetrahydrobenzo[...)
Affinity DataIC50: 1.00E+5nMAssay Description:The fluorescence polarization (FP) assay was performed as described in the reference (Bioorg Med Chem. 2010. 18:6031-6043).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPutative heat shock protein HSP 90-alpha A4(Human)
Shandong University

LigandPNGBDBM166681(4-(7-Hydroxy-4,5,6,7-tetrahydro-benzo[d]isoxazol-3...)
Affinity DataIC50: 1.00E+5nMAssay Description:The fluorescence polarization (FP) assay was performed as described in the reference (Bioorg Med Chem. 2010. 18:6031-6043).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed