Compile Data Set for Download or QSAR
Report error Found 81 Enz. Inhib. hit(s) with Target = 'Proto-oncogene Wnt-3'
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265554((2S)-N-(tert-Butyl)-2-{[4-({[5-(phenylsulfonyl)-2-...)
Affinity DataEC50:  30nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265500(tert-Butyl (2S)-2-{[4-({[5-(Phenylsulfonyl)-2-(tri...)
Affinity DataEC50:  60nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265502(tert-Butyl(5S)-2-oxo-5-{[4-({[5-(Phenylsulfonyl)-2...)
Affinity DataEC50:  90nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265545(N-[1-(1-Isobutyryl-L-prolyl)piperidin-4-yl]-5-(phe...)
Affinity DataEC50:  90nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265553((2S)-N-Ethyl-2-{[4-({[5-(phenylsulfonyl)-2-(triflu...)
Affinity DataEC50:  90nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265547(N-{1-[1-(3,3-Dimethylbutanoyl)-L-prolyl]piperidin-...)
Affinity DataEC50:  120nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265580((2S)-N,N-Dimethyl-2-{[4-({[5-(phenylsulfonyl)-2-(t...)
Affinity DataEC50:  160nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265480(N-[1-(Morpholin-4-ylacetyl)piperidin-4-yl]-5-(phen...)
Affinity DataEC50:  160nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265479(5-(Phenylsulfonyl)-N-[1-(pyrrolidin-1-ylacetyl)pip...)
Affinity DataEC50:  190nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294836(CHEMBL551506 | CHEMBL1956162 | 4-((1R,2S,6R,7S)-3,...)
Affinity DataEC50:  200nMAssay Description:Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265501(tert-Butyl (2R)-2-{[4-({[5-(Phenylsulfonyl)-2-(tri...)
Affinity DataEC50:  210nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265582(N-[1-(1-Methyl-L-prolyl)piperidin-4-yl]-5-(phenyls...)
Affinity DataEC50:  230nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265499(N-[1-(1H-Imidazol-1-ylacetyl)piperidin-4-yl]-5-(ph...)
Affinity DataEC50:  230nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265505(N-[1-(5-oxo-L-Prolyl)piperidin-4-yl]-5-(phenylsulf...)
Affinity DataEC50:  240nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265544(N-[1-(1-Acetyl-L-prolyl)piperidin-4-yl]-5-(phenyls...)
Affinity DataEC50:  250nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265481(5-(Phenylsulfonyl)-N-[1-(piperazin-1-ylacetyl)pipe...)
Affinity DataEC50:  250nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265546(N-{1-[1-(2,2-Dimethylpropanoyl)-L-prolyl]piperidin...)
Affinity DataEC50:  270nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265581(N-{1-[1-(Morpholin-4-ylcarbonyl)-L-prolyl]piperidi...)
Affinity DataEC50:  280nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265469(N-[1-(N,N-Dimethylglycyl)piperidin-4-yl]-5-(phenyl...)
Affinity DataEC50:  280nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265555((2S)-N-Phenyl-2-{[4-({[5-(phenylsulfonyl)-2-(trifl...)
Affinity DataEC50:  310nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265548(N-[1-(N,N-Dimethylglycyl-L-prolyl)piperidin-4-yl]-...)
Affinity DataEC50:  310nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265584(N-{1-[1-(Cyclohexylmethyl)-L-prolyl]piperidin-4-yl...)
Affinity DataEC50:  320nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265503(5-(Phenylsulfonyl)-N-(1-L-prolylpiperidin-4-yl)-2-...)
Affinity DataEC50:  350nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265552(N-[1-(1-Isonicotinoyl-L-prolyl)piperidin-4-yl]-5-(...)
Affinity DataEC50:  350nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265550(N-[1-(1-Benzoyl-L-prolyl)piperidin-4-yl]-5-(phenyl...)
Affinity DataEC50:  380nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294827(4-((1R,2S,6R,7S)-3,5-Dioxo-4-aza-tricyclo[5.2.1.0*...)
Affinity DataEC50:  400nMAssay Description:Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265583(N-{1-[1-(3,3-Dimethylbutyl)-L-prolyl]piperidin-4-y...)
Affinity DataEC50:  450nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265549(N-{1-[1-(Cyclohexylcarbonyl)-L-prolyl]piperidin-4-...)
Affinity DataEC50:  460nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265468(N-[1-(N-Methylglycyl)piperidin-4-yl]-5-(phenylsulf...)
Affinity DataEC50:  620nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265467(5-(Phenylsulfonyl)-N-piperidin-4-yl-2-(trifluorome...)
Affinity DataEC50:  650nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265504((R)-5-(phenylsulfonyl)-N-(1-(pyrrolidine-2-carbony...)
Affinity DataEC50:  710nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265585(N-[1-(1-Benzyl-L-prolyl)piperidin-4-yl]-5-(phenyls...)
Affinity DataEC50:  720nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294787(4-((1R,2S,6R,7S)-3,5-Dioxo-4-aza-tricyclo[5.2.1.0*...)
Affinity DataEC50:  800nMAssay Description:Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265551(N-(1-{1-[4-(Dimethylamino)benzoyl]-L-prolyl}piperi...)
Affinity DataEC50:  830nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294828(4-((1R,2S,6R,7S)-3,5-Dioxo-4-aza-tricyclo[5.2.1.0*...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294829(4-((1R,2S,6R,7S)-3,5-Dioxo-4-aza-tricyclo[5.2.1.0*...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294799(N-(4-Bromo-phenyl)-4-((1R,2S,6R,7S)-3,5-dioxo-4-az...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294789(4-((1R,2S,6R,7S)-3,5-Dioxo-4-aza-tricyclo[5.2.1.0*...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294823(2-Chloro-4-((1R,2S,6R,7S)-3,5-dioxo-4-aza-tricyclo...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294817(trans-4-((1R,2S,6R,7S)-3,5-Dioxo-4-aza-tricyclo[5....)
Affinity DataEC50:  2.00E+3nMAssay Description:Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294824(4-((1R,2S,6R,7S)-3,5-Dioxo-4-aza-tricyclo[5.2.1.0*...)
Affinity DataEC50:  2.00E+3nMAssay Description:Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294798(N-(4-Chloro-phenyl)-4-((1R,2S,6R,7S)-3,5-dioxo-4-a...)
Affinity DataEC50:  3.00E+3nMAssay Description:Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294806(N-(3,4-Difluoro-phenyl)-4-((1R,2S,6R,7S)-dioxo-4-a...)
Affinity DataEC50:  3.00E+3nMAssay Description:Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294797(4-((1R,2S,6R,7S)-3,5-Dioxo-4-aza-tricyclo[5.2.1.0*...)
Affinity DataEC50:  4.00E+3nMAssay Description:Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294835(CHEMBL562310 | CHEMBL551505 | N-(Quinolin-8-yl)-4-...)
Affinity DataEC50:  5.00E+3nMAssay Description:Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294807(N-(3,4-Dichloro-phenyl)-4-((1R,2S,6R,7S)-dioxo-4-a...)
Affinity DataEC50:  5.00E+3nMAssay Description:Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294796(N-(3-Bromo-phenyl)-4-((1R,2S,6R,7S)-3,5-dioxo-4-az...)
Affinity DataEC50:  9.00E+3nMAssay Description:Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294801(N-(2,4-Difluoro-phenyl)-4-((1R,2S,6R,7S)-dioxo-4-a...)
Affinity DataEC50:  9.00E+3nMAssay Description:Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294816(4-((1R,2S,6R,7S)-3,5-Dioxo-4-aza-tricyclo[5.2.1.0*...)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene Wnt-3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294833(4-((1R,2S,6R,7S)-3,5-Dioxo-4-aza-tricyclo[5.2.1.0*...)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
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