Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with Target = 'Protein tyrosine phosphatase type IVA 1'
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM396097(US10308663, JMS-631-053)
Affinity DataIC50: 50nMAssay Description:Inhibition of PTP4A1 (unknown origin) expressed in Escherichia coli assessed as reduction in hydrolysis using DIFMUP as substrate incubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50059084(CHEMBL3393171 | US10308663, Thienopyridone (5))
Affinity DataIC50: 130nMAssay Description:Inhibition of full-length human brain His6-tagged PRL-1 expressed in Escherichia coli using TAMRA-Thr-Ala-Asp-Ile-Tyr(PO3H2)-Glu-NH2 peptide as subst...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50059084(CHEMBL3393171 | US10308663, Thienopyridone (5))
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant human His-6-tagged PTP4A1 expressed in Escherichia coli assessed as increase in polarization using TAMRAThr-Ala-Asp-Ile-Tyr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50059084(CHEMBL3393171 | US10308663, Thienopyridone (5))
Affinity DataIC50: 173nMAssay Description:Inhibition of full length human fusion His6 tagged PRL1 expressed in Escherichia coli using TAMRA-Thr-Ala-Asp-Ile-Tyr(PO3H2)-Glu-NH2 substrate by imm...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM45440(4-[5-(4-carbamimidoylphenoxy)pentoxy]benzenecarbox...)
Affinity DataIC50: 300nMAssay Description:Inhibition of PTP4A1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50312665(Sodium 2-(2-Fluorophenyl)-6,7-methylenedioxyquinol...)
Affinity DataIC50: 676nMAssay Description:Inhibition of human PTP4A1 by enzyme assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50391711(CHEMBL2146958)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of PRL1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50535761(CHEMBL4539375)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PTP4A1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50391713(CHEMBL2146956)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of PRL1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50059140(CHEMBL3393148)
Affinity DataIC50: 3.13E+4nMAssay Description:Inhibition of PRL1 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50391714(CHEMBL2146957)
Affinity DataIC50: 3.72E+4nMAssay Description:Inhibition of PRL1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50387974(CHEMBL2057830)
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of PRL1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50343142(N-(4-butylphenyl)-2-oxo-1,2-dihydrobenzo[cd]indole...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human PRL1 expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50343147(N1-(furan-2-ylmethyl)-N2-(1-(4-(4-methoxyphenyl)pi...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human PRL1 expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50343148(N1-(1-(4-(4-fluorophenyl)piperazin-1-yl)-1-(thioph...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human PRL1 expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50059141(CHEMBL3393149)
Affinity DataIC50: 5.67E+4nMAssay Description:Inhibition of PRL1 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50059084(CHEMBL3393171 | US10308663, Thienopyridone (5))
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of PRL1 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50059086(CHEMBL3393146)
Affinity DataIC50: 7.01E+4nMAssay Description:Inhibition of PRL1 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50059142(CHEMBL3393150)
Affinity DataIC50: 8.91E+4nMAssay Description:Inhibition of PRL1 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50391712(CHEMBL2146959)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PRL1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50391715(CHEMBL2146960)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PRL1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50237957(4-(2-((2,5-dioxoimidazolidin-4-ylidene)methyl)-1H-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PRL1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50059143(CHEMBL3393151)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of PRL1 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50059139(CHEMBL3393147)
Affinity DataIC50: 2.09E+5nMAssay Description:Inhibition of PRL1 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50059085(CHEBI:8830 | Rhodanine)
Affinity DataIC50: 2.09E+5nMAssay Description:Inhibition of PRL1 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed