Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with Target = 'Protein mono-ADP-ribosyltransferase PARP6'
TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50628429(CHEMBL5402698)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of PARP6 (unknown origin) using biotinylated NAD+ as substrate by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50499822(CHEMBL3740897)
Affinity DataIC50: 83nMAssay Description:Inhibition of PARP6 (unknown origin) using histone as substrate incubated for 30 mins by microplate reader based analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50499822(CHEMBL3740897)
Affinity DataIC50: 83nMAssay Description:Inhibition of full length human PARP6 expressed in a Baculovirus infected Sf9 insect cells using activated DNA as substrate after 1 hr by streptavidi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged PARP6 (1 to 630(end) residues) expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50499821(CHEMBL3740104)
Affinity DataIC50: 640nMAssay Description:Inhibition of full length human PARP6 expressed in a Baculovirus infected Sf9 insect cells using activated DNA as substrate after 1 hr by streptavidi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of full length human PARP6 expressed in a Baculovirus infected Sf9 insect cells using activated DNA as substrate after 1 hr by streptavidi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50593627(CHEMBL5199558)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant PARP6 (1 to 630 residues) expressed in Sf9 insect cells by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 3.48E+3nMAssay Description:Inhibition of PARP6 (unknown origin) using biotinylated NAD+ as substrate by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM707189(N-cyclopropyl-5-(4-((7-ethyl-6-oxo-5,6-dihydro-1,5...)
Affinity DataIC50: 6.86E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50616441(CHEMBL5404785)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of N-terminal 6 His-MBP tagged human PARP6 expressed in Sf21 cells incubated for 18 hrs in presence of NAD+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553942(US11325906, Example 6)
Affinity DataIC50: 8.20E+3nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50434127(CHEMBL2381633)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PARP6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50616435(CHEMBL5431108)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal 6 His-MBP tagged human PARP6 expressed in Sf21 cells incubated for 18 hrs in presence of NAD+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553969(US11325906, Example 32)
Affinity DataIC50: 1.00E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553967(US11325906, Example 30)
Affinity DataIC50: 1.00E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50318567(2-[4-(trifluoromethyl)phenyl]-7,8-dihydro-5H-thiop...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PARP6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50434157(CHEMBL2381958 | US9340549, 78)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PARP6 (unknown origin) using histone as substrate after 1 hr by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50505333(CHEMBL4437173)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length PARP6 expressed in Baculovirus infected Sf9 cells using biotinylated substrate afte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553948(US11325906, Example 12)
Affinity DataIC50: 1.10E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553951(US11325906, Example 14)
Affinity DataIC50: 1.10E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553966(US11325906, Example 29)
Affinity DataIC50: 1.40E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553939(US11325906, Example 3)
Affinity DataIC50: 1.40E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553938(US11325906, Example 2)
Affinity DataIC50: 1.40E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553959(US11325906, Example 22)
Affinity DataIC50: 1.60E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553944(US11325906, Example 8)
Affinity DataIC50: 1.80E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553940(US11325906, Example 4)
Affinity DataIC50: 1.90E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553943(US11325906, Example 7)
Affinity DataIC50: 2.20E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553947(US11325906, Example 11)
Affinity DataIC50: 2.20E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553941(US11325906, Example 5)
Affinity DataIC50: 2.30E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553946(US11325906, Example 10)
Affinity DataIC50: 2.60E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553968(US11325906, Example 31)
Affinity DataIC50: 2.80E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553956(US11325906, Example 19)
Affinity DataIC50: 2.90E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553955(US11325906, Example 18)
Affinity DataIC50: 2.90E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553950(US11325906, Example 13)
Affinity DataIC50: 3.00E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553953(US11325906, Example 16)
Affinity DataIC50: 3.10E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553958(US11325906, Example 21)
Affinity DataIC50: 3.30E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553937(US11325906, Example 1)
Affinity DataIC50: 3.40E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553945(US11325906, Example 9)
Affinity DataIC50: 4.70E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM431646(5-[[(2S)-1-(3-Oxo-3-[4-[5-(trifluoromethyl)pyrimid...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PARP6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553954(US11325906, Example 17)
Affinity DataIC50: 5.90E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553952(US11325906, Example 15)
Affinity DataIC50: 8.00E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553965(US11325906, Example 28)
Affinity DataIC50: 1.00E+5nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553964(US11325906, Example 27)
Affinity DataIC50: 1.00E+5nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553963(US11325906, Example 26)
Affinity DataIC50: 1.00E+5nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553962(US11325906, Example 25)
Affinity DataIC50: 1.00E+5nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553961(US11325906, Example 24)
Affinity DataIC50: 1.00E+5nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553960(US11325906, Example 23)
Affinity DataIC50: 1.00E+5nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM207624(US9260440, 69 | US9617273, Example 69 | US10501467...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PARP-6 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM553957(US11325906, Example 20)
Affinity DataIC50: 1.00E+5nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails
US Patent