Compile Data Set for Download or QSAR
Report error Found 2613 Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta'
LigandPNGBDBM50126041(6-[3-(4-Cyano-phenyl)-3-hydroxy-3-(3-methyl-3H-imi...)
Affinity DataEC50:  2.70nMAssay Description:Inhibition of farnesylation in NIH-3T3H-ras cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50076790(Lithium; (S)-2-{[2'-methyl-5-(5-pyridin-3-yl-furan...)
Affinity DataEC50:  0.300nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50076788(Lithium; (S)-2-({5-[5-(3-fluoro-phenyl)-furan-2-yl...)
Affinity DataEC50:  10nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50076795(Lithium; (S)-2-({5-[5-(4-dimethylamino-phenyl)-fur...)
Affinity DataEC50:  0.900nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50076800(Lithium; (S)-2-({5-[5-(4-acetyl-phenyl)-furan-2-yl...)
Affinity DataEC50: >1nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50076797(Lithium; (S)-2-{[2'-methyl-5-(5-phenyl-furan-2-ylm...)
Affinity DataEC50: >1nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50076794(Lithium; (S)-2-({5-[5-(4-isopropyl-phenyl)-furan-2...)
Affinity DataEC50:  0.780nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50076801(Lithium; (S)-2-({2'-methyl-5-[5-(3-nitro-phenyl)-f...)
Affinity DataEC50:  10nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50076806(Lithium; (S)-2-({5-[5-(4-methoxy-phenyl)-furan-2-y...)
Affinity DataEC50: >1nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50076793(Lithium; (S)-2-({2'-methyl-5-[5-(4-methylsulfanyl-...)
Affinity DataEC50:  10nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50076802(Lithium; (S)-2-{[2'-methyl-5-(5-pyridin-4-yl-furan...)
Affinity DataEC50: >0.300nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50076810(Lithium; (S)-4-methylsulfanyl-2-({2'-methyl-5-[5-(...)
Affinity DataEC50:  1.20nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50076808(Lithium; (S)-2-{[2'-methyl-5-(5-pyridin-2-yl-furan...)
Affinity DataEC50: >0.300nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50076807(Lithium; (S)-2-({5-[5-(3-methoxy-phenyl)-furan-2-y...)
Affinity DataEC50: >1nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50076811(Lithium; (S)-2-({5-[5-(4-chloro-phenyl)-furan-2-yl...)
Affinity DataEC50:  0.100nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50076791(Lithium; (S)-4-methylsulfanyl-2-{[2'-methyl-5-(5-p...)
Affinity DataEC50:  1.80nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50076803(Lithium; (S)-2-({5-[5-(2-fluoro-phenyl)-furan-2-yl...)
Affinity DataEC50: >1nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50076809(Lithium; (S)-2-({5-[5-(4-formyl-phenyl)-furan-2-yl...)
Affinity DataEC50: >1nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50076813(Lithium; (S)-2-({5-[5-(2-methoxy-phenyl)-furan-2-y...)
Affinity DataEC50: >1nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50076798(Lithium; (S)-2-({5-[5-(4-fluoro-phenyl)-furan-2-yl...)
Affinity DataEC50:  1.5nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50098002(N-Isopropyl-2-(1-methyl-2-phenyl-1H-indol-3-yl)-N-...)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of K-Ras farnesylation in PSN-1 cells without GGT1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50098002(N-Isopropyl-2-(1-methyl-2-phenyl-1H-indol-3-yl)-N-...)
Affinity DataEC50:  1.98E+3nMAssay Description:Inhibition of HDJ-2 farnesylation in PSN-1 cells at without GGT1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50098005(N-Isopropyl-2-(1-methyl-2-o-tolyl-1H-indol-3-yl)-N...)
Affinity DataEC50:  1.06E+3nMAssay Description:Inhibition of HDJ-2 farnesylation in PSN-1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50098002(N-Isopropyl-2-(1-methyl-2-phenyl-1H-indol-3-yl)-N-...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of HDJ-2 farnesylation in PSN-1 cells with 100 nM GGT1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50098002(N-Isopropyl-2-(1-methyl-2-phenyl-1H-indol-3-yl)-N-...)
Affinity DataEC50:  1.33E+3nMAssay Description:Inhibition of HDJ-2 farnesylation in PSN-1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112383(17-(5,5,5-trifluoropentyl)-19-oxa-2,5,10,12-tetraa...)
Affinity DataEC50:  6.90nMAssay Description:Inhibition of HDJ2 farnesylation in PSN-1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112379(1-(3-Chloro-phenyl)-4-{2-[3-(2-methoxy-4'-trifluor...)
Affinity DataEC50:  28nMAssay Description:Inhibition of HDJ2 farnesylation in PSN-1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM13382(CHEMBL158553 | 3-(3-chlorophenyl)-4-{[(4-cyanophen...)
Affinity DataEC50:  5.20nMAssay Description:Reduced farnesylation of H-ras transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50126024(4-[3-(5,3'-Dichloro-biphenyl-2-yl)-1-hydroxy-1-(3-...)
Affinity DataEC50:  100nMAssay Description:Inhibition of farnesylation in NIH-3T3H-ras cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50126039(4-[1-Hydroxy-1-(3-methyl-3H-imidazol-4-yl)-3-(4-pe...)
Affinity DataEC50:  3.80nMAssay Description:Inhibition of farnesylation in NIH-3T3H-ras cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50126026(3-Benzo[1,3]dioxol-5-yl-4-[3-(4-cyano-phenyl)-3-hy...)
Affinity DataEC50:  1.40nMAssay Description:Inhibition of farnesylation in NIH-3T3H-ras cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50126032(5-[3-(4-Cyano-phenyl)-1-hydroxy-1-(3-methyl-3H-imi...)
Affinity DataEC50:  9.80nMAssay Description:Inhibition of farnesylation in NIH-3T3H-ras cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50126040(6-[3-(4-Cyano-phenyl)-3-hydroxy-3-(3-methyl-3H-imi...)
Affinity DataEC50:  1.20nMAssay Description:Inhibition of farnesylation in NIH-3T3H-ras cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50126037(4-[1-Hydroxy-1-(3-methyl-3H-imidazol-4-yl)-3-(6-me...)
Affinity DataEC50:  49nMAssay Description:Inhibition of farnesylation in NIH-3T3H-ras cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50126042(4-[3-(5-Chloro-3'-methoxy-biphenyl-2-yl)-1-hydroxy...)
Affinity DataEC50:  4nMAssay Description:Inhibition of farnesylation in NIH-3T3H-ras cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50126031(4-[3-(4-Ethyl-phenyl)-1-hydroxy-1-(3-methyl-3H-imi...)
Affinity DataEC50:  130nMAssay Description:Inhibition of farnesylation in NIH-3T3H-ras cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50126045(4-[3-(4-Chloro-phenyl)-1-hydroxy-1-(3-methyl-3H-im...)
Affinity DataEC50:  9.5nMAssay Description:Inhibition of farnesylation in NIH-3T3H-ras cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50126035(4-[3-(4-Cyano-phenyl)-1-hydroxy-1-(3-methyl-3H-imi...)
Affinity DataEC50:  7.90nMAssay Description:Inhibition of farnesylation in NIH-3T3H-ras cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50126036(6-[3-(4-Cyano-phenyl)-3-hydroxy-3-(3-methyl-3H-imi...)
Affinity DataEC50:  0.100nMAssay Description:Inhibition of farnesylation in NIH-3T3H-ras cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50126028(3',5'-Dichloro-6-[3-(4-cyano-phenyl)-3-hydroxy-3-(...)
Affinity DataEC50:  3.90nMAssay Description:Inhibition of farnesylation in NIH-3T3H-ras cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50126030(4-[1-Hydroxy-1-(3-methyl-3H-imidazol-4-yl)-3-pheny...)
Affinity DataEC50:  170nMAssay Description:Inhibition of farnesylation in NIH-3T3H-ras cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50126041(6-[3-(4-Cyano-phenyl)-3-hydroxy-3-(3-methyl-3H-imi...)
Affinity DataEC50:  2.70nMAssay Description:Inhibition of farnesylation in NIH-3T3H-ras cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50126025(4-[3-(4-Cyano-phenyl)-1-hydroxy-1-(3-methyl-3H-imi...)
Affinity DataEC50: <1nMAssay Description:Inhibition of farnesylation in NIH-3T3H-ras cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50126044(5-[(4-Cyano-phenyl)-hydroxy-(3-methyl-3H-imidazol-...)
Affinity DataEC50: <1nMAssay Description:Inhibition of farnesylation in NIH-3T3H-ras cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50126034(4-[1-Hydroxy-3-(3'-methoxy-5-pentanoyl-biphenyl-2-...)
Affinity DataEC50: <0.100nMAssay Description:Inhibition of farnesylation in NIH-3T3H-ras cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50135356(6-[(2'-Chloro-6-cyano-biphenyl-3-yl)-(3-methyl-3H-...)
Affinity DataEC50: >100nMAssay Description:In vitro effective concentration against farnesyltransferase (FT)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50135358(6-[(3-Bromo-4-cyano-phenyl)-(3-methyl-3H-imidazol-...)
Affinity DataEC50:  39nMAssay Description:In vitro effective concentration against farnesyltransferase (FT)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17325(CHEMBL29982 | (2S)-2-[(4-{[butyl(2-cyclohexylethyl...)
Affinity DataEC50:  16nMAssay Description:In vitro effective concentration against farnesyltransferase (FT)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50135366(6-[(3-Chloro-4-cyano-phenyl)-(3-methyl-3H-imidazol...)
Affinity DataEC50:  16nMAssay Description:In vitro effective concentration against farnesyltransferase (FT)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50135365(6-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataEC50: >100nMAssay Description:In vitro effective concentration against farnesyltransferase (FT)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 2613 total ) | Next | Last >>
Jump to: