Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 7'
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50089221(CHEMBL3577854)
Affinity DataKd:  3.70E+4nMAssay Description:Binding affinity to human full length PRMT7 by Surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50597884(CHEMBL5185202)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of PRMT7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human PRMT7 using GST-GAR as substrate by hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50598017(CHEMBL5206272)
Affinity DataIC50: 220nMAssay Description:Inhibition of human full length recombinant his-tagged PRMT7 (2 to 692 residues) using GST-GAR as substrate incubated for 20 mins in presence of [3H]...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50598020(CHEMBL5202088)
Affinity DataIC50: 226nMAssay Description:Inhibition of human full length recombinant his-tagged PRMT7 (2 to 692 residues) using GST-GAR as substrate incubated for 20 mins in presence of [3H]...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50598015(CHEMBL5199380)
Affinity DataIC50: 320nMAssay Description:Inhibition of human full length recombinant his-tagged PRMT7 (2 to 692 residues) using GST-GAR as substrate incubated for 20 mins in presence of [3H]...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50598018(CHEMBL5180108)
Affinity DataIC50: 410nMAssay Description:Inhibition of human full length recombinant his-tagged PRMT7 (2 to 692 residues) using GST-GAR as substrate incubated for 20 mins in presence of [3H]...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50628241(CHEMBL5408585)
Affinity DataIC50: 540nMAssay Description:Inhibition of N-terminal/C-terminal His-tagged human recombinant full-length PRMT7 (2 to 692 residues) using histone GST-GAR as substrate and 3H-SAM ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50598016(CHEMBL5170047)
Affinity DataIC50: 550nMAssay Description:Inhibition of human full length recombinant his-tagged PRMT7 (2 to 692 residues) using GST-GAR as substrate incubated for 20 mins in presence of [3H]...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50598019(CHEMBL5186617)
Affinity DataIC50: 631nMAssay Description:Inhibition of human full length recombinant his-tagged PRMT7 (2 to 692 residues) using GST-GAR as substrate incubated for 20 mins in presence of [3H]...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50598022(CHEMBL5173678)
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of human full length recombinant his-tagged PRMT7 (2 to 692 residues) using GST-GAR as substrate incubated for 20 mins in presence of [3H]...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50598021(CHEMBL5191769)
Affinity DataIC50: 4.68E+3nMAssay Description:Inhibition of human full length recombinant his-tagged PRMT7 (2 to 692 residues) using GST-GAR as substrate incubated for 20 mins in presence of [3H]...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50628242(CHEMBL5396270)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of N-terminal/C-terminal His-tagged human recombinant full-length PRMT7 (2 to 692 residues) using histone GST-GAR as substrate and 3H-SAM ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50089221(CHEMBL3577854)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human full length PRMT7 expressed in Sf9 cells assessed as inhibition of H2B[23-37] methylationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50396023(CHEMBL2169919)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of human full length PRMT7 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50247634(CHEMBL4067973)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PRMT7 (unknown origin) using [3H]-SAM as co-factor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50550092(CHEMBL4740128)
Affinity DataIC50: 2.33E+4nMAssay Description:Inhibition of recombinant GST-tagged PRMT7 (unknown origin) expressed in Escherichia coli using biotin-labeled SMD1 as substrate incubated for 120 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50550091(CHEMBL4648477)
Affinity DataIC50: 2.36E+4nMAssay Description:Inhibition of recombinant GST-tagged PRMT7 (unknown origin) expressed in Escherichia coli using biotin-labeled SMD1 as substrate incubated for 120 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50525201(CHEMBL4463124)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant full-length human PRMT7 expressed in Sf9 insect cells using Ac-KKDGKKRKRSRKESYK-biotin as substrate measured after 30 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50089221(CHEMBL3577854)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human full length PRMT7 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50609300(CHEMBL5266562)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PRMT7 (unknown origin) by radioisotope based assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human full length PRMT7 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50551136(CHEMBL4757320)
Affinity DataIC50: 6.15E+4nMAssay Description:Inhibition of recombinant human PRMT7 using GST-GAR as substrate by hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50551131(CHEMBL4787257)
Affinity DataIC50: 6.94E+4nMAssay Description:Inhibition of recombinant human PRMT7 using GST-GAR as substrate by hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50529897(CHEMBL4468383)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length human N-terminal FLAG-tagged PRMT7 expressed in Sf9 insect cells preincubated for 15 mins followed by substrate...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50529897(CHEMBL4468383)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length human N-terminal FLAG-tagged PRMT7 expressed in Sf9 insect cells preincubated for 15 mins followed by substrate...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50532859(CHEMBL4436627)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PRMT7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50532859(CHEMBL4436627)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PRMT7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50238541(CHEMBL4092336)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human N-terminal His-tagged full length PRMT7 expressed in baculovirus using of histone H4 as substrate preincubated for 15...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM223137(P5i-6)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:All in vitro enzymatic assays were carried out by Shanghai ChemPartner Co. (998 Halei Road, Pudong New Area, Shanghai, 201203, China). To measure the...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50550095(CHEMBL4792295)
Affinity DataIC50: 1.26E+5nMAssay Description:Inhibition of recombinant GST-tagged PRMT7 (unknown origin) expressed in Escherichia coli using biotin-labeled SMD1 as substrate incubated for 120 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50550093(CHEMBL4755950)
Affinity DataIC50: 2.48E+5nMAssay Description:Inhibition of recombinant GST-tagged PRMT7 (unknown origin) expressed in Escherichia coli using biotin-labeled SMD1 as substrate incubated for 120 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50550094(CHEMBL4740956)
Affinity DataIC50: 2.88E+5nMAssay Description:Inhibition of recombinant GST-tagged PRMT7 (unknown origin) expressed in Escherichia coli using biotin-labeled SMD1 as substrate incubated for 120 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed