Compile Data Set for Download or QSAR
Report error Found 512 Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 1'
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50206427(AMI-1 | 7,7'-carbonylbis(azanediyl)bis(4-hydroxyna...)
Affinity DataKd:  810nMAssay Description:Binding affinity to human recombinant GST-PRMT1 expressed Escherichia coli BL21 by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 1(Rat)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50243294(CHEMBL4094513)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) incubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50095354(CHEMBL3589030)
Affinity DataIC50: 4nMAssay Description:Inhibition of N-terminal GST tagged full-length human PRMT1 expressed in high five insect cells pre-incubated for 30 mins before addition of a [3H]SA...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50095432(CHEMBL3589026)
Affinity DataIC50: 4nMAssay Description:Inhibition of N-terminal GST tagged full-length human PRMT1 expressed in high five insect cells pre-incubated for 30 mins before addition of a [3H]SA...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM178103(MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human PRMT1 assessed as inhibition of methylation activity using biotin-labeled peptide as substrate and [3H]-SAM by scintillation prox...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM178103(MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...)
Affinity DataIC50: 4nMAssay Description:Inhibition of PRMT1 (unknown origin) using biotinylated histone H4 (1 to 24 residues) as substrate in presence of [3H]SAM by scintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM178103(MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...)
Affinity DataIC50: 4nMAssay Description:Inhibition of PRMT1 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50095353(CHEMBL3589031)
Affinity DataIC50: 5nMAssay Description:Inhibition of N-terminal GST tagged full-length human PRMT1 expressed in high five insect cells pre-incubated for 30 mins before addition of a [3H]SA...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50095356(CHEMBL3589028)
Affinity DataIC50: 5nMAssay Description:Inhibition of N-terminal GST tagged full-length human PRMT1 expressed in high five insect cells pre-incubated for 30 mins before addition of a [3H]SA...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 1(Rat)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50243294(CHEMBL4094513)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) using biotinylated H4 peptide (1 to 21 residues) as s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 1(Rat)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50243295(CHEMBL4084293)
Affinity DataIC50: 6nMAssay Description:Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) using biotinylated H4 peptide (1 to 21 residues) as s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50095355(CHEMBL3589029)
Affinity DataIC50: 7nMAssay Description:Inhibition of N-terminal GST tagged full-length human PRMT1 expressed in high five insect cells pre-incubated for 30 mins before addition of a [3H]SA...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50095357(CHEMBL3589027)
Affinity DataIC50: 7nMAssay Description:Inhibition of N-terminal GST tagged full-length human PRMT1 expressed in high five insect cells pre-incubated for 30 mins before addition of a [3H]SA...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50095348(CHEMBL3589036)
Affinity DataIC50: 8nMAssay Description:Inhibition of N-terminal GST tagged full-length human PRMT1 expressed in high five insect cells pre-incubated for 30 mins before addition of a [3H]SA...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50095351(CHEMBL3589033)
Affinity DataIC50: 13nMAssay Description:Inhibition of N-terminal GST tagged full-length human PRMT1 expressed in high five insect cells pre-incubated for 30 mins before addition of a [3H]SA...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50095433(CHEMBL3589913)
Affinity DataIC50: 13nMAssay Description:Inhibition of N-terminal GST tagged full-length human PRMT1 expressed in high five insect cells pre-incubated for 30 mins before addition of a [3H]SA...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50095347(CHEMBL3589037)
Affinity DataIC50: 14nMAssay Description:Inhibition of N-terminal GST tagged full-length human PRMT1 expressed in high five insect cells pre-incubated for 30 mins before addition of a [3H]SA...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50095352(CHEMBL3589032)
Affinity DataIC50: 14nMAssay Description:Inhibition of N-terminal GST tagged full-length human PRMT1 expressed in high five insect cells pre-incubated for 30 mins before addition of a [3H]SA...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50095442(CHEMBL3589038)
Affinity DataIC50: 16nMAssay Description:Inhibition of N-terminal GST tagged full-length human PRMT1 expressed in high five insect cells pre-incubated for 30 mins before addition of a [3H]SA...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50095434(CHEMBL3589912)
Affinity DataIC50: 18nMAssay Description:Inhibition of N-terminal GST tagged full-length human PRMT1 expressed in high five insect cells pre-incubated for 30 mins before addition of a [3H]SA...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM502122(US11028083, Example 91)
Affinity DataIC50: 22nMAssay Description:This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 50 mM Hepes ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM502138(US11028083, Example 100b)
Affinity DataIC50: 22nMAssay Description:This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 50 mM Hepes ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM502103(US11028083, Example 80b | US11028083, Example 79b)
Affinity DataIC50: 24nMAssay Description:This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 50 mM Hepes ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM502116(US11028083, Example 87b)
Affinity DataIC50: 24nMAssay Description:This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 50 mM Hepes ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein arginine N-methyltransferase 1 [11-371](Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50095438(CHEMBL3589042)
Affinity DataIC50: 26nMAssay Description:Inhibition of N-terminal GST tagged full-length human PRMT1 expressed in high five insect cells pre-incubated for 30 mins before addition of a [3H]SA...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50095350(CHEMBL3589034)
Affinity DataIC50: 27nMAssay Description:Inhibition of N-terminal GST tagged full-length human PRMT1 expressed in high five insect cells pre-incubated for 30 mins before addition of a [3H]SA...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM502127(US11028083, Example 94b)
Affinity DataIC50: 27nMAssay Description:This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 50 mM Hepes ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM502129(US11028083, Example 95b)
Affinity DataIC50: 27nMAssay Description:This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 50 mM Hepes ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM502057(N1-((3-(4,4-dimethyl- cyclohexyl)-5,6- dihydro-4H-...)
Affinity DataIC50: 29nMAssay Description:This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 50 mM Hepes ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM502120(US11028083, Example 89b)
Affinity DataIC50: 29nMAssay Description:This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 50 mM Hepes ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM502140(US11028083, Example 101b)
Affinity DataIC50: 29nMAssay Description:This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 50 mM Hepes ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM502114(US11028083, Example 86b)
Affinity DataIC50: 30nMAssay Description:This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 50 mM Hepes ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM502128(US11028083, Example 95a)
Affinity DataIC50: 30nMAssay Description:This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 50 mM Hepes ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM178103(MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human PRMT1 using S-adenosyl-L-methionine (3H) as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50502498(CHEMBL4518534)
Affinity DataIC50: 31nMAssay Description:Inhibition of PRMT1 (unknown origin) by hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM502009(US11028083, Example 5b)
Affinity DataIC50: 33nMAssay Description:This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 50 mM Hepes ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM502074(US11028083, Example 65a)
Affinity DataIC50: 34nMAssay Description:This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 50 mM Hepes ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM502107(US11028083, Example 82a | US11028083, Example 82b)
Affinity DataIC50: 34nMAssay Description:This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 50 mM Hepes ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM502131(US11028083, Example 96b)
Affinity DataIC50: 34nMAssay Description:This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 50 mM Hepes ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM502103(US11028083, Example 80b | US11028083, Example 79b)
Affinity DataIC50: 36nMAssay Description:This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 50 mM Hepes ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM502019(N1,N2-dimethyl-N1-((3- (spiro[5.5]undecan-3- yl)-5...)
Affinity DataIC50: 37nMAssay Description:This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 50 mM Hepes ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM502143(US11028083, Example 103b)
Affinity DataIC50: 37nMAssay Description:This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 50 mM Hepes ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM502055(N1,N2-dimethyl-N1-((3- (spiro[4.5]decan-8-yl)- 5,6...)
Affinity DataIC50: 39nMAssay Description:This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 50 mM Hepes ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM502075(US11028083, Example 65b)
Affinity DataIC50: 40nMAssay Description:This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 50 mM Hepes ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM502115(US11028083, Example 87a)
Affinity DataIC50: 40nMAssay Description:This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 50 mM Hepes ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM502113(US11028083, Example 86a)
Affinity DataIC50: 41nMAssay Description:This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 50 mM Hepes ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM502022(Ethyl 1-methyl-4-(2- ((methyl(2-(methyl- amino)eth...)
Affinity DataIC50: 42nMAssay Description:This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 50 mM Hepes ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM502102(US11028083, Example 80a | US11028083, Example 79a)
Affinity DataIC50: 42nMAssay Description:This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 50 mM Hepes ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein arginine N-methyltransferase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM502136(N1-((3-(4,4-bis(methoxy- methyl)cyclohexyl)-5,5- d...)
Affinity DataIC50: 42nMAssay Description:This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 50 mM Hepes ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein arginine N-methyltransferase 1 [11-371](Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50095349(CHEMBL3589035)
Affinity DataIC50: 43nMAssay Description:Inhibition of N-terminal GST tagged full-length human PRMT1 expressed in high five insect cells pre-incubated for 30 mins before addition of a [3H]SA...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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