Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with Target = 'Proteasome subunit beta type-6'
TargetProteasome subunit beta type-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50069989(CHEMBL325041 | (R)-3-methyl-1-((S)-3-phenyl-2-(pyr...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human 20S immunoproteasome beta1 subunit using Ac-nLPnLD-AMC as substrate preincubated for 2 hrs followed by substrate addition and mea...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProteasome subunit beta type-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50398609(CHEMBL2141296 | MLN2238 | Ixazomib | NINLARO | IXA...)
Affinity DataIC50: 64nMAssay Description:Inhibition of human 20S immunoproteasome beta1 subunit using Ac-nLPnLD-AMC as substrate preincubated for 2 hrs followed by substrate addition and mea...More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetProteasome subunit beta type-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50277889(CHEMBL451887 | CARFILZOMIB)
Affinity DataIC50: 890nMAssay Description:Inhibition of human 20S immunoproteasome beta1 subunit using Ac-nLPnLD-AMC as substrate preincubated for 2 hrs followed by substrate addition and mea...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProteasome subunit beta type-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50601642(CHEMBL5188533)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of human 20S immunoproteasome beta1 subunit using Ac-nLPnLD-AMC as substrate preincubated for 2 hrs followed by substrate addition and mea...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProteasome subunit beta type-6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50601643(CHEMBL5184466)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human 20S immunoproteasome beta1 subunit using Ac-nLPnLD-AMC as substrate preincubated for 2 hrs followed by substrate addition and mea...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProteasome subunit beta type-6(Baker's yeast)
Cnrs-Université

Curated by ChEMBL
LigandPNGBDBM50185622(Apam-YET | CHEMBL210325)
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of post acid activity of yeast 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteasome subunit beta type-6(Baker's yeast)
Cnrs-Université

Curated by ChEMBL
LigandPNGBDBM50185643((S)-2-{(S)-4-carboxy-2-[(S)-2-hexadecanoylamino-3-...)
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition of post acid activity of yeast 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteasome subunit beta type-6(Baker's yeast)
Cnrs-Université

Curated by ChEMBL
LigandPNGBDBM50185630(Pam-YDL | CHEMBL210871)
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition of post acid activity of yeast 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteasome subunit beta type-6(Baker's yeast)
Cnrs-Université

Curated by ChEMBL
LigandPNGBDBM50185650(Pam-YET | CHEMBL209568)
Affinity DataKi:  2.10E+4nMAssay Description:Inhibition of post acid activity of yeast 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteasome subunit beta type-6(Baker's yeast)
Cnrs-Université

Curated by ChEMBL
LigandPNGBDBM50185638((S)-2-{(S)-4-Carboxy-2-[(S)-2-hexanoylamino-3-(4-h...)
Affinity DataKi:  5.90E+4nMAssay Description:Inhibition of post acid activity of yeast 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteasome subunit beta type-6(Baker's yeast)
Cnrs-Université

Curated by ChEMBL
LigandPNGBDBM50185628((S)-2-{(S)-4-carboxy-2-[(S)-2-dodecanoylamino-3-(4...)
Affinity DataKi:  6.20E+4nMAssay Description:Inhibition of post acid activity of yeast 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteasome subunit beta type-6(Baker's yeast)
Cnrs-Université

Curated by ChEMBL
LigandPNGBDBM50185632((S)-2-{(S)-4-carboxy-2-[(S)-2-decanoylamino-3-(4-h...)
Affinity DataKi:  7.20E+4nMAssay Description:Inhibition of post acid activity of yeast 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteasome subunit beta type-6(Baker's yeast)
Cnrs-Université

Curated by ChEMBL
LigandPNGBDBM50185648((S)-4-((S)-1-carboxy-2-(4-hydroxyphenyl)ethylamino...)
Affinity DataKi: >8.00E+4nMAssay Description:Inhibition of post acid activity of yeast 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteasome subunit beta type-6(Baker's yeast)
Cnrs-Université

Curated by ChEMBL
LigandPNGBDBM50185618((S)-4-((S)-1-carboxy-2-(4-hydroxyphenyl)ethylamino...)
Affinity DataKi: >8.00E+4nMAssay Description:Inhibition of post acid activity of yeast 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteasome subunit beta type-6(Baker's yeast)
Cnrs-Université

Curated by ChEMBL
LigandPNGBDBM50185620(TVTFKF | CHEMBL378655)
Affinity DataKi:  1.48E+5nMAssay Description:Inhibition of post acid activity of yeast 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteasome subunit beta type-6(Baker's yeast)
Cnrs-Université

Curated by ChEMBL
LigandPNGBDBM50185629(TITYKF | CHEMBL277277)
Affinity DataKi:  2.60E+5nMAssay Description:Inhibition of post acid activity of yeast 20S proteasome at 625 uMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteasome subunit beta type-6(Baker's yeast)
Cnrs-Université

Curated by ChEMBL
LigandPNGBDBM50185639(TITYDL | CHEMBL378045)
Affinity DataKi: >6.25E+5nMAssay Description:Inhibition of post acid activity of yeast 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteasome subunit beta type-6(Baker's yeast)
Cnrs-Université

Curated by ChEMBL
LigandPNGBDBM50185634(TITFDY | CHEMBL378002)
Affinity DataKi: >6.25E+5nMAssay Description:Inhibition of post acid activity of yeast 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteasome subunit beta type-6(Baker's yeast)
Cnrs-Université

Curated by ChEMBL
LigandPNGBDBM50185631(TISYDY | CHEMBL426136)
Affinity DataKi: >6.25E+5nMAssay Description:Inhibition of post acid activity of yeast 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteasome subunit beta type-6(Baker's yeast)
Cnrs-Université

Curated by ChEMBL
LigandPNGBDBM50185623(TVSYKF | CHEMBL426505)
Affinity DataKi: >6.25E+5nMAssay Description:Inhibition of post acid activity of yeast 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteasome subunit beta type-6(Baker's yeast)
Cnrs-Université

Curated by ChEMBL
LigandPNGBDBM50185635(TVTYKY | CHEMBL380055)
Affinity DataKi: >6.25E+5nMAssay Description:Inhibition of post acid activity of yeast 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProteasome subunit beta type-6(Baker's yeast)
Cnrs-Université

Curated by ChEMBL
LigandPNGBDBM50185652(TITYDF | CHEMBL426138)
Affinity DataKi: >6.25E+5nMAssay Description:Inhibition of post acid activity of yeast 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed