Compile Data Set for Download or QSAR
Report error Found 76 Enz. Inhib. hit(s) with Target = 'Prostacyclin synthase' Sort by
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022222(2-Imidazol-1-ylmethyl-3-methyl-benzofuran-5-carbox...)
Affinity DataIC50: 10nMAssay Description:Inhibition of porcine aorta prostacyclin PGI-2 synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036377((Z)-6-{2-[1-(4-Fluoro-phenoxy)-1-methyl-ethyl]-4-p...)
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036359((Z)-6-{2-[2-(4-Fluoro-phenyl)-1,1-dimethyl-ethyl]-...)
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036344((Z)-6-{2-[1-(2-Methanesulfonyl-phenoxy)-1-methyl-e...)
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036376((Z)-6-[2-(2,4-Dichloro-phenyl)-4-pyridin-3-yl-[1,3...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036351((Z)-6-{2-[1-(2-Cyano-phenoxy)-1-methyl-ethyl]-4-py...)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036362((Z)-6-{2-[1-(4-Bromo-phenoxy)-1-methyl-ethyl]-4-py...)
Affinity DataIC50: 4.00E+3nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036370((Z)-6-{2-[1-(4-Cyano-phenoxy)-1-methyl-ethyl]-4-py...)
Affinity DataIC50: 4.00E+3nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036387((Z)-6-{2-[1-(4-Acetyl-2-nitro-phenoxy)-1-methyl-et...)
Affinity DataIC50: 4.00E+3nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036362((Z)-6-{2-[1-(4-Bromo-phenoxy)-1-methyl-ethyl]-4-py...)
Affinity DataIC50: 4.00E+3nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036345((Z)-6-{2-[1-Methyl-1-(4-methylsulfanyl-2-nitro-phe...)
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036356((Z)-6-{2-[2-(2-Cyano-4-fluoro-phenyl)-1,1-dimethyl...)
Affinity DataIC50: 7.00E+3nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036372((Z)-6-{2-[1-(2-Bromo-phenoxy)-1-methyl-ethyl]-4-py...)
Affinity DataIC50: 7.00E+3nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036386((Z)-6-{2-[1-(4-Methanesulfonyl-phenoxy)-1-methyl-e...)
Affinity DataIC50: 8.00E+3nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036354((Z)-6-{2-[1-(4-Fluoro-2-nitro-phenoxy)-1-methyl-et...)
Affinity DataIC50: 9.00E+3nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036363((Z)-6-[2-(3,4-Dichloro-phenyl)-4-pyridin-3-yl-[1,3...)
Affinity DataIC50: 9.00E+3nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036361((Z)-6-{2-[1-(2-Cyano-4-methyl-phenoxy)-1-methyl-et...)
Affinity DataIC50: 1.20E+4nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036361((Z)-6-{2-[1-(2-Cyano-4-methyl-phenoxy)-1-methyl-et...)
Affinity DataIC50: 1.20E+4nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036368((Z)-6-[2-(1,1-Dimethyl-2-phenyl-ethyl)-4-pyridin-3...)
Affinity DataIC50: 1.30E+4nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036374((Z)-6-[2-(4-Nitro-phenyl)-4-pyridin-3-yl-[1,3]diox...)
Affinity DataIC50: 1.30E+4nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036380((Z)-6-{2-[2-(2-Cyano-phenyl)-1,1-dimethyl-ethyl]-4...)
Affinity DataIC50: 1.40E+4nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036346((Z)-6-{2-[1-(4-Methoxy-2-nitro-phenoxy)-1-methyl-e...)
Affinity DataIC50: 2.30E+4nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036382((Z)-6-[2-(1-Methyl-1-p-tolyloxy-ethyl)-4-pyridin-3...)
Affinity DataIC50: 2.50E+4nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036360((Z)-6-{2-[1-Methyl-1-(4-methylsulfanyl-phenoxy)-et...)
Affinity DataIC50: 3.20E+4nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036365((Z)-6-{2-[1-Methyl-1-(4-methyl-2-nitro-phenoxy)-et...)
Affinity DataIC50: 3.30E+4nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036365((Z)-6-{2-[1-Methyl-1-(4-methyl-2-nitro-phenoxy)-et...)
Affinity DataIC50: 3.30E+4nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036355((Z)-6-{2-[1-(2-Cyano-4-fluoro-phenoxy)-1-methyl-et...)
Affinity DataIC50: 3.70E+4nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036349((Z)-6-{2-[1-(3-Fluoro-phenoxy)-1-methyl-ethyl]-4-p...)
Affinity DataIC50: 4.00E+4nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036369((Z)-6-{2-[1-(2-Methoxy-phenoxy)-1-methyl-ethyl]-4-...)
Affinity DataIC50: 5.10E+4nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036373((Z)-6-{2-[1-(2-Cyano-6-methyl-phenoxy)-1-methyl-et...)
Affinity DataIC50: 6.00E+4nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036350(2-{1-[5-((Z)-5-Carboxy-pent-2-enyl)-4-pyridin-3-yl...)
Affinity DataIC50: 7.30E+4nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036371((Z)-6-[2-(1-Methyl-1-phenoxy-ethyl)-4-pyridin-3-yl...)
Affinity DataIC50: 7.50E+4nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036364((Z)-6-[2-(4-Cyano-phenyl)-4-pyridin-3-yl-[1,3]diox...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50025953(6-Imidazo[1,5-a]pyridin-5-yl-hexanoic acid | CGS-1...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against prostacyclin synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036385((Z)-6-{2-[1-(2-Hydroxy-phenoxy)-1-methyl-ethyl]-4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM7962(CHEMBL537708 | 4-[2-(1H-imidazol-1-yl)ethoxy]benzo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036358((Z)-6-[2-(2-Cyano-phenyl)-4-pyridin-3-yl-[1,3]diox...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036381((Z)-6-{2-[1-(4-Methoxy-phenoxy)-1-methyl-ethyl]-4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50313205(4-Hydroxy-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[e...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human prostacyclin synthase in IL-1-beta-stimulated human RASF cells assessed as PGF1alpha levels after 50 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50010960((E)-7-Phenyl-7-pyridin-3-yl-hept-6-enoic acid | CV...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036353((Z)-6-{2-[1-Methyl-1-(2-methylsulfanyl-phenoxy)-et...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036378((Z)-6-{2-[1-(2-Cyano-5-methyl-phenoxy)-1-methyl-et...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022217(2-Imidazol-1-ylmethyl-benzo[b]thiophene-5-carboxyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of porcine aorta prostacyclin PGI-2 synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022119(3-(5-Chloro-3-imidazol-1-ylmethyl-indol-1-yl)-prop...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022122(3-(3-Imidazol-1-ylmethyl-5-methoxy-indol-1-yl)-pro...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50000317(3-(3-Imidazol-1-ylmethyl-2-methyl-indol-1-yl)-prop...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022124(3-(3-Imidazol-1-ylmethyl-indol-1-yl)-propionic aci...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022126((3-Imidazol-1-ylmethyl-indol-1-yl)-acetic acid | C...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022121(3-Imidazol-1-ylmethyl-2-isopropyl-1H-indole(UK-347...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022125(3-(5-Dimethylamino-3-imidazol-1-ylmethyl-indol-1-y...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Displayed 1 to 50 (of 76 total ) | Next | Last >>
Jump to: