Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with Target = 'Prolyl 4-hydroxylase subunit alpha-1'
TargetProlyl 4-hydroxylase subunit alpha-1(Human)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50042876([2,2']Bipyridinyl-5,5'-dicarboxylic acid | CHEMBL3...)
Affinity DataIC50: 840nMpH: 7.8Assay Description:Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Human)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50092609(CHEMBL3586252)
Affinity DataIC50: 1.20E+3nMpH: 7.8Assay Description:Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | Oxalylglycine | [(carboxymethyl)carb...)
Affinity DataIC50: 2.89E+3nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM26114(CHEMBL88972 | pyridine-2,5-dicarboxylic acid | pyr...)
Affinity DataIC50: 5.18E+3nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Human)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM26114(CHEMBL88972 | pyridine-2,5-dicarboxylic acid | pyr...)
Affinity DataIC50: 1.50E+4nMpH: 7.8Assay Description:Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000866(CHEMBL451545 | 2-(Oxalyl-amino)-propionic acid (0....)
Affinity DataIC50: 3.82E+4nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000865(CHEMBL314979 | 2-(Oxalyl-amino)-propionic acid)
Affinity DataIC50: 9.07E+4nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000864(CHEMBL314175 | N-(2-Methanesulfonylamino-2-oxo-eth...)
Affinity DataIC50: 4.14E+5nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000863(CHEMBL88472 | 2-(Oxalyl-amino)-propionic acid)
Affinity DataIC50: 6.21E+5nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylase at 50 ug/mLMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Human)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50042876([2,2']Bipyridinyl-5,5'-dicarboxylic acid | CHEMBL3...)
Affinity DataKi:  140nMpH: 7.8Assay Description:Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Human)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50092609(CHEMBL3586252)
Affinity DataKi:  200nMpH: 7.8Assay Description:Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | Oxalylglycine | [(carboxymethyl)carb...)
Affinity DataKi:  540nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM26114(CHEMBL88972 | pyridine-2,5-dicarboxylic acid | pyr...)
Affinity DataKi:  800nMAssay Description:Inhibitory activity against prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Human)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM26114(CHEMBL88972 | pyridine-2,5-dicarboxylic acid | pyr...)
Affinity DataKi:  2.60E+3nMpH: 7.8Assay Description:Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM50100861(Protocatechuic acid (M1) | Protocatechuic acid | 3...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM52946(SMR000326727 | MLS001056737 | 3,4-Dihydroxyphenyla...)
Affinity DataKi:  9.00E+3nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM92714(3,4-Dihydroxymandelate, XVI)
Affinity DataKi:  9.00E+3nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM41957(3-[3,4-bis(oxidanyl)phenyl]propanoic acid | 3-(3,4...)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM4375(3,4-Dihydroxycinnamate, XVII | cid_689043 | Caffei...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM26188(1,2-Dihydroxybenzene, XI | CHEMBL280998 | benzene-...)
Affinity DataKi:  2.50E+4nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM50031472(CHEMBL307145 | 1,2,3-Trihydroxybenzene, XIV | pyro...)
Affinity DataKi:  3.00E+4nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM50085536(Gallic Acid, F | 3,4,5-Trihydroxybenzoate, X | CHE...)
Affinity DataKi:  3.00E+4nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM92456(2,3-Dihydroxybenzoate, IV | 2,3-dihydroxybenzoic a...)
Affinity DataKi:  7.00E+4nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM74208(beta-Resorcylic acid | MLS001055408 | SMR001227190...)
Affinity DataKi:  5.30E+5nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM16419(Phenylacetate, XIX | Benzeneacetic acid | phenylac...)
Affinity DataKi: >2.00E+7nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM50070030(5-(1,2-Dihydroxy-ethyl)-3,4-dihydroxy-dihydro-fura...)
Affinity DataKi: >2.00E+7nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM92715((+)-Mandelate, XXI | (-)-Mandelate, XX)
Affinity DataKi: >2.00E+7nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM92715((+)-Mandelate, XXI | (-)-Mandelate, XX)
Affinity DataKi: >2.00E+7nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM26193(salicylic acid | 2-Hydroxybenzoate, I | CHEMBL424 ...)
Affinity DataKi:  2.30E+6nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM26190(CHEMBL537 | benzene-1,4-diol | Hydroquinone, HQ | ...)
Affinity DataKi:  1.40E+7nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM26189(CHEMBL24147 | benzene-1,3-diol | 1,3-dihydroxybenz...)
Affinity DataKi:  1.02E+7nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM50336490(3,5-dihydroxybenzoic acid | 3,5-dihydroxybenzoicac...)
Affinity DataKi:  9.00E+6nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM92712(2,6-Dihydroxybenzoate, VII)
Affinity DataKi:  1.10E+6nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM50335808(2,5-Dihydroxybenzoate, VI | gentisic acid | CHEMBL...)
Affinity DataKi:  1.40E+6nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM26194(4-Hydroxybenzoate, III | CHEMBL441343 | p-Hydroxyb...)
Affinity DataKi:  3.20E+6nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM50336491(CHEMBL65369 | 3-Hydroxybenzoate, II | 3-hydroxyben...)
Affinity DataKi: >2.00E+7nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails
PubMed