Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily B member 1'
TargetPotassium voltage-gated channel subfamily B member 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM168436(US9675591, SKA-19)
Affinity DataEC50:  2.23E+4nMpH: 7.35 T: 2°CAssay Description:All experiments were conducted at room temperature (22-24° C.) with an EPC-10 amplifier and Pulse software (HEKA, Lambrecht/Pfalz, Germany) in the wh...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetPotassium voltage-gated channel subfamily B member 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50593373(CHEMBL5182581)
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of Kv2.1 channel (unknown origin) by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50088573(CHEMBL3577208)
Affinity DataIC50: 590nMAssay Description:Inhibition of Kv2.1 channel in human INS1 cells assessed as inhibition of outward K+ current by electrophysiology/patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily B member 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50088572(CHEMBL3577209)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Kv2.1 channel in human INS1 cells assessed as inhibition of outward K+ current by electrophysiology/patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50213094((1R,2R)-1-(3,4-dichlorophenethoxy)-2-(4-morpholiny...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of rat potassium channel Kv2.1 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50213092((1R,2R)-1-(1-naphthalenethoxy)-2-(4-morpholinyl)cy...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of rat potassium channel Kv2.1 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50213093((1R,2R)-1-(1-naphthalenethoxy)-2-(3-ketopyrrolidin...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of rat potassium channel Kv2.1 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50213093((1R,2R)-1-(1-naphthalenethoxy)-2-(3-ketopyrrolidin...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of rat potassium channel Kv2.1 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50213095((1S,2S)-1-(1-Naphthalenethoxy)-2-(3-ketopyrrolidin...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of rat potassium channel Kv2.1 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed