Compile Data Set for Download or QSAR
Report error Found 1656 Enz. Inhib. hit(s) with Target = 'Phospholipase A2'
TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50236230(ursodeoxy cholic acid | 2-((R)-4-((3R,5S,7S,8R,9S,...)
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to human pancreatic recombinant 1B PLA2 expressed in Escherichia coli by resonance energy transfer assay in presence of trimethyl-am...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM21680(Cholic Acid | (R)-4-((3R,5S,7R,8R,10S,12S,13R,14S,...)
Affinity DataKd: >1.50E+5nMAssay Description:Binding affinity to human pancreatic recombinant 1B PLA2 expressed in Escherichia coli by resonance energy transfer assay in presence of trimethyl-am...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Rat)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50029031(CHEMBL223344 | 1-Amino-4-{4-[4-chloro-6-(3-sulfo-p...)
Affinity DataEC50:  6.43E+3nMAssay Description:Antagonist activity at rat PA2 transfected in xenopus oocyte cellMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50053109([1-Aminooxalyl-3-(2-benzyl-benzyl)-2-ethyl-indoliz...)
Affinity DataIC50: 1.30nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50053136((1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-methyl-indo...)
Affinity DataIC50: 1.40nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50601469(CHEMBL5172164)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human group IIA phospholipase A2 preincubated with compound for 10 mins followed by enzyme addition and measured after 30 mins by PC/DO...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50053106([1-Aminooxalyl-2-ethyl-3-(3-trifluoromethyl-benzyl...)
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, major isoenzyme(Pig)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50055367([3-Aminooxalyl-1-(3-chloro-benzyl)-2-ethyl-1H-indo...)
Affinity DataIC50: 3nMAssay Description:Compound was tested for inhibition of porcine secreted pancreatic PLA2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50055371((3-aminooxalyl-1-biphenyl-2-ylmethyl-2-methyl-1H-i...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50053108((1-Aminooxalyl-3-benzyl-2-methyl-indolizin-8-yloxy...)
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50053137((1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-ethyl-indol...)
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50053102([1-Aminooxalyl-3-(3-chloro-benzyl)-2-ethyl-indoliz...)
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50161301(2-[4-(2-Benzenesulfonylamino-2-oxo-ethoxy)-1-benzy...)
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against human nonpancreatic secretory phospholipase A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50053137((1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-ethyl-indol...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human group IIA phospholipase A2 preincubated with compound for 10 mins followed by enzyme addition and measured after 30 mins by PC/DO...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50055374([3-Aminooxalyl-1-(2-benzyl-benzyl)-2-ethyl-1H-indo...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50055374([3-Aminooxalyl-1-(2-benzyl-benzyl)-2-ethyl-1H-indo...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50161305((3-Aminooxalyl-1-cyclohexylmethyl-2-methyl-2,3-dih...)
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration against human nonpancreatic secretory phospholipase A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50053114((1-Aminooxalyl-3-biphenyl-3-ylmethyl-2-ethyl-indol...)
Affinity DataIC50: 4.20nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50053133((1-Aminooxalyl-3-benzyl-2-ethyl-indolizin-8-yloxy)...)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50053096([1-Aminooxalyl-3-(4-butyl-benzyl)-2-ethyl-indolizi...)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50053123((1-Aminooxalyl-2-ethyl-3-naphthalen-1-ylmethyl-ind...)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50601472(CHEMBL5208632)
Affinity DataIC50: 5nMAssay Description:Inhibition of human group IIA phospholipase A2 preincubated with compound for 10 mins followed by enzyme addition and measured after 30 mins by PC/DO...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50053102([1-Aminooxalyl-3-(3-chloro-benzyl)-2-ethyl-indoliz...)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50053137((1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-ethyl-indol...)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50055371((3-aminooxalyl-1-biphenyl-2-ylmethyl-2-methyl-1H-i...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50055379((3-Aminooxalyl-1-biphenyl-2-ylmethyl-2-cyclopropyl...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50055401((3-Aminooxalyl-1-biphenyl-2-ylmethyl-2-ethyl-1H-in...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50055378([3-Aminooxalyl-1-(2,6-dichloro-benzyl)-2-methyl-1H...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50055401((3-Aminooxalyl-1-biphenyl-2-ylmethyl-2-ethyl-1H-in...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50055387((R)-2-(3-Aminooxalyl-1-benzyl-2-methyl-1H-indol-4-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50053109([1-Aminooxalyl-3-(2-benzyl-benzyl)-2-ethyl-indoliz...)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50053147((1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-cyclopropyl...)
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50161293((3-Aminooxalyl-1-benzyl-2-methyl-1,6,7,8-tetrahydr...)
Affinity DataIC50: 6nMAssay Description:Inhibitory concentration against human nonpancreatic secretory phospholipase A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50055371((3-aminooxalyl-1-biphenyl-2-ylmethyl-2-methyl-1H-i...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human group IIA phospholipase A2 incubated for 1 hrs by scintillation counter analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50053137((1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-ethyl-indol...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human group IIA phospholipase A2 incubated for 30 mins by automatic plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50055366(Varespladib sodium | (3-Aminooxalyl-1-benzyl-2-eth...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50055367([3-Aminooxalyl-1-(3-chloro-benzyl)-2-ethyl-1H-indo...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, major isoenzyme(Pig)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50055384((3-Aminooxalyl-1-biphenyl-3-ylmethyl-2-methyl-1H-i...)
Affinity DataIC50: 7nMAssay Description:Compound was tested for inhibition of porcine secretory pancreatic Phospholipase A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50055366(Varespladib sodium | (3-Aminooxalyl-1-benzyl-2-eth...)
Affinity DataIC50: 7nMAssay Description:Inhibitory concentration against human nonpancreatic secretory phospholipase A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50161299((3-Aminooxalyl-1-benzyl-2-ethyl-1,6,7,8-tetrahydro...)
Affinity DataIC50: 7nMAssay Description:Inhibitory concentration against human nonpancreatic secretory phospholipase A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50161301(2-[4-(2-Benzenesulfonylamino-2-oxo-ethoxy)-1-benzy...)
Affinity DataIC50: 7nMAssay Description:Inhibitory concentration against human nonpancreatic secretory phospholipase A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, major isoenzyme(Pig)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50055384((3-Aminooxalyl-1-biphenyl-3-ylmethyl-2-methyl-1H-i...)
Affinity DataIC50: 7nMAssay Description:Inhibition of pig group IB phospholipase A2 incubated for 1 hrs by scintillation counter analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50601470(CHEMBL5177527)
Affinity DataIC50: 7nMAssay Description:Inhibition of human group IIA phospholipase A2 incubated for 30 mins by automatic plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50601470(CHEMBL5177527)
Affinity DataIC50: 7nMAssay Description:Inhibition of human group IIA phospholipase A2 preincubated with compound for 10 mins followed by enzyme addition and measured after 30 mins by PC/DO...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50053095((1-Aminooxalyl-2-ethyl-3-naphthalen-2-ylmethyl-ind...)
Affinity DataIC50: 7.30nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50053108((1-Aminooxalyl-3-benzyl-2-methyl-indolizin-8-yloxy...)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50055380((3-Aminooxalyl-1-benzyl-2-ethyl-6-methyl-1H-indol-...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50055370((3-Aminooxalyl-2-methyl-1-octyl-1H-indol-4-yloxy)-...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50055380((3-Aminooxalyl-1-benzyl-2-ethyl-6-methyl-1H-indol-...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50055384((3-Aminooxalyl-1-biphenyl-3-ylmethyl-2-methyl-1H-i...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 1656 total ) | Next | Last >>
Jump to: