Compile Data Set for Download or QSAR
Report error Found 63 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform [144-1102]'
LigandPNGBDBM489229(US10961236, Example 3 | N-{6-[(5-{2-[(1S)-1-Cyclop...)
Affinity DataIC50: 0.800nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489258(US10961236, Example 31 | 2-[(1S)-1-Cyclopropylethy...)
Affinity DataIC50: 0.800nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489232(US10961236, Example 6 | 2-[(1S)-1-Cyclopropylethyl...)
Affinity DataIC50: 0.800nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489289(US10961236, Example 62 | 2-[(2S)-Butan-2-yl]-N-met...)
Affinity DataIC50: 0.800nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489272(US10961236, Example 45 | 2-[(1S)-1-Cyclopropylethy...)
Affinity DataIC50: 0.800nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489238(US10961236, Example 11 | 5-(4-Methyl-2-{[6-(2-oxoi...)
Affinity DataIC50: 0.800nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489261(US10961236, Example 34 | 2-[(1S)-1-Cyclopropylethy...)
Affinity DataIC50: 0.800nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489240(US10961236, Example 13 | N-{6-[(5-{2-[(1S)-1-Cyclo...)
Affinity DataIC50: 0.800nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489245(US10961236, Example 18 | N-{6-[(5-{2-[(1S)-1-Cyclo...)
Affinity DataIC50: 0.800nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489265(US10961236, Example 38 | 2-tert-Butyl-N-methyl-6-(...)
Affinity DataIC50: 0.800nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489241(US10961236, Example 14 | N-{6-[(5-{2-[(1S)-1-Cyclo...)
Affinity DataIC50: 0.900nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489254(US10961236, Example 27 | N-Ethyl-6-(4-methyl-2-{[6...)
Affinity DataIC50: 0.900nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489286(US10961236, Example 59 | 2-[(1S)-1-Cyclopropylethy...)
Affinity DataIC50: 0.900nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489251(US10961236, Example 24 | 2-[(1S)-1-Cyclopropylethy...)
Affinity DataIC50: 0.900nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489282(US10961236, Example 55 | 2-[(1S)-1-Cyclopropylethy...)
Affinity DataIC50: 0.900nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489247(US10961236, Example 20 | 2-[(1S)-1-Cyclopropylethy...)
Affinity DataIC50: 0.900nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489281(US10961236, Example 54 | 2-[(1S)-1-Cyclopropylethy...)
Affinity DataIC50: 0.900nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489239(US10961236, Example 12 | 5-(4-Methyl-2-{[6-(2-oxo-...)
Affinity DataIC50: 0.900nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489237(US10961236, Example 10 | 5-(4-Methyl-2-{[6-(2-oxop...)
Affinity DataIC50: 0.900nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489234(US10961236, Example 7 | 2-[(1S)-1-Cyclopropylethyl...)
Affinity DataIC50: 0.900nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489227(US10961236, Example 1 | 2-[(1S)-1-Cyclopropylethyl...)
Affinity DataIC50: 0.900nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489228(US10961236, Example 2 | N-{6-[(5-{2-[(1S)-1-Cyclop...)
Affinity DataIC50: 0.900nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489273(US10961236, Example 46 | 2-[(1S)-1-Cyclopropylethy...)
Affinity DataIC50: 1nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489262(US10961236, Example 35 | 2-[(1S)-1-Cyclopropylethy...)
Affinity DataIC50: 1nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489270(US10961236, Example 43 | 2-[(1S)-1-Cyclopropylethy...)
Affinity DataIC50: 1nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489283(US10961236, Example 56 | 2-[(1S)-1-Cyclopropylethy...)
Affinity DataIC50: 1nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489269(US10961236, Example 42 | 2-[(1S)-1-Cyclopropylethy...)
Affinity DataIC50: 1nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489249(US10961236, Example 22 | 2-[(1S)-1-Cyclopropylethy...)
Affinity DataIC50: 1nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489246(US10961236, Example 19 | 2-[(1S)-1-Cyclopropylethy...)
Affinity DataIC50: 1nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489288(US10961236, Example 61 | 2-[(2S)-Butan-2-yl]-N-met...)
Affinity DataIC50: 1nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489242(US10961236, Example 15 | (2R)-N-{6-[(5-{2-[(1S)-1-...)
Affinity DataIC50: 1nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489236(US10961236, Example 9 | 6-{6-[(5-{2-[(1S)-1-Cyclop...)
Affinity DataIC50: 1nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489230(US10961236, Example 4 | 2-[(1S)-1-Cyclopropylethyl...)
Affinity DataIC50: 1nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489253(US10961236, Example 26 | N-{6-[(5-{2-[(1S)-1-Cyclo...)
Affinity DataIC50: 1.10nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489252(US10961236, Example 25 | N-Methyl-6-(4-methyl-2-{[...)
Affinity DataIC50: 1.10nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489248(US10961236, Example 21 | 2-[(1S)-1-Cyclopropylethy...)
Affinity DataIC50: 1.10nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489244(US10961236, Example 17 | N-{6-[(5-{2-[(1S)-1-Cyclo...)
Affinity DataIC50: 1.10nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489264(US10961236, Example 37 | 6-(4-Methyl-2-{[6-(2-oxop...)
Affinity DataIC50: 1.10nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489285(US10961236, Example 58 | 2-[(1S)-1-Cyclopropylethy...)
Affinity DataIC50: 1.20nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489284(US10961236, Example 57 | 2-[(1S)-1-Cyclopropylethy...)
Affinity DataIC50: 1.20nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489287(US10961236, Example 60 | 6-[2-({6-[(3S)-3-Hydroxy-...)
Affinity DataIC50: 1.20nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489271(US10961236, Example 44 | 2-[(1S)-1-Cyclopropylethy...)
Affinity DataIC50: 1.20nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489290(US10961236, Example 63 | N-Methyl-6-(4-methyl-2-{[...)
Affinity DataIC50: 1.20nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489263(US10961236, Example 36 | 6-(4-Methyl-2-{[6-(2-oxop...)
Affinity DataIC50: 1.20nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489231(US10961236, Example 5 | 2-[(1S)-1-Cyclopropylethyl...)
Affinity DataIC50: 1.20nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489243(US10961236, Example 16 | (2S)-N-{6-[(5-{2-[(1S)-1-...)
Affinity DataIC50: 1.20nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489260(US10961236, Example 33 | 2-[(1S)-1-Cyclopropylethy...)
Affinity DataIC50: 1.20nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489268(US10961236, Example 41 | 2-[(1S)-1-Cyclopropylethy...)
Affinity DataIC50: 1.30nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489274(US10961236, Example 47 | 2-[(1S)-1-Cyclopropylethy...)
Affinity DataIC50: 1.30nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM489259(US10961236, Example 32 | 2-[(1S)-1-Cyclopropylethy...)
Affinity DataIC50: 1.30nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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