Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with Target = 'Phosphatidylcholine-sterol acyltransferase'
TargetPhosphatidylcholine-sterol acyltransferase(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM303816((+)-4,5-Dihydroxy-4-(trifluoromethyl)-3-{1-[5-(tri...)
Affinity DataEC50:  4nMAssay Description:A fraction composed of HDL3 (1.125More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetPhosphatidylcholine-sterol acyltransferase(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM303817((+)-cis-5-Hydroxy-4-(trifluoromethyl)-3-{1-[2-(tri...)
Affinity DataEC50:  18nMAssay Description:A fraction composed of HDL3 (1.125More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetPhosphatidylcholine-sterol acyltransferase(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM92615(Difluoroketone phospholipid analogue, 3)
Affinity DataIC50: 28nMpH: 7.5 T: 2°CAssay Description:The phospholipase A2 activity of LCAT was assayed using lecithin and apoA-I containing [9,10-3H] dipalmitoylphosphatidylcholine (DPPC) and measuremen...More data for this Ligand-Target Pair
In DepthDetails

TargetPhosphatidylcholine-sterol acyltransferase(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM92614(Difluoroketone phospholipid analogue, 2)
Affinity DataIC50: 60nMpH: 7.5 T: 2°CAssay Description:The phospholipase A2 activity of LCAT was assayed using lecithin and apoA-I containing [9,10-3H] dipalmitoylphosphatidylcholine (DPPC) and measuremen...More data for this Ligand-Target Pair
In DepthDetails

TargetPhosphatidylcholine-sterol acyltransferase(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM92616(Difluoroketone phospholipid analogue, 4)
Affinity DataIC50: 60nMpH: 7.5 T: 2°CAssay Description:The phospholipase A2 activity of LCAT was assayed using lecithin and apoA-I containing [9,10-3H] dipalmitoylphosphatidylcholine (DPPC) and measuremen...More data for this Ligand-Target Pair
In DepthDetails

TargetPhosphatidylcholine-sterol acyltransferase(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM92613(Difluoroketone phospholipid analogue, 1)
Affinity DataIC50: 500nMpH: 7.5 T: 2°CAssay Description:The phospholipase A2 activity of LCAT was assayed using lecithin and apoA-I containing [9,10-3H] dipalmitoylphosphatidylcholine (DPPC) and measuremen...More data for this Ligand-Target Pair
In DepthDetails