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Report error Found 94 Enz. Inhib. hit(s) with Target = 'Peptidyl-prolyl cis-trans isomerase D'
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50169545(CHEMBL3805631)
Affinity DataKd:  149nMAssay Description:Binding affinity to human recombinant cyclophilin D by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50164669(CHEMBL3798305)
Affinity DataKd:  5.12E+3nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM139995(US8901295, F428)
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50339005(5-(4-((4R,5R,E)-5-((2S,5S,11S,14S,17S,20S,23R,26S,...)
Affinity DataKd:  101nMAssay Description:Inhibition of cyclosporin binding to Cyp40 by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50164668(CHEMBL3799575)
Affinity DataKd:  5.40E+3nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50164667(CHEMBL3798755)
Affinity DataKd:  2.80E+3nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50164670(CHEMBL3799597)
Affinity DataKd:  1.20E+3nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50164667(CHEMBL3798755)
Affinity DataKd:  230nMAssay Description:Binding affinity to CypD (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50164677(CHEMBL3799315)
Affinity DataKd:  5.76E+4nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50164666(CHEMBL3799661)
Affinity DataKd:  410nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50164673(CHEMBL3797905)
Affinity DataKd:  2.27E+4nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50164675(CHEMBL3798445)
Affinity DataKd:  8.80E+3nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50164665(CHEMBL3797675)
Affinity DataKd:  9.73E+4nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50164664(CHEMBL3800488)
Affinity DataKd:  9.73E+4nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataKd:  30nMAssay Description:Binding affinity to CypD (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50164674(CHEMBL3799875)
Affinity DataKd:  3.41E+4nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50164676(CHEMBL3797711)
Affinity DataKd:  8.20E+4nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataKd:  13nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50164672(CHEMBL3799069)
Affinity DataKd:  1.27E+5nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50164671(CHEMBL3798030)
Affinity DataKd:  9.25E+4nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human recombinant cyclophilin D using Suc-AAPF-MCA as substrate preincubated for 1 hr followed by substrate addition measured per milli...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516083(CHEMBL4470490)
Affinity DataIC50: 4nMAssay Description:Inhibition of CypD (unknown origin) PPIase activity using N-Suc-AAPF-p-nitroanilide as substrate preincubated with enzyme for 10 mins followed by chy...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516083(CHEMBL4470490)
Affinity DataIC50: 60nMAssay Description:Displacement of fluorescein labelled cyclosporine A derivative from human recombinant CypD (30 to 207 residues) expressed in Escherichia coli cells i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516100(CHEMBL4466871)
Affinity DataIC50: 190nMAssay Description:Displacement of fluorescein labelled cyclosporine A derivative from human recombinant CypD (30 to 207 residues) expressed in Escherichia coli cells i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516080(CHEMBL4464178)
Affinity DataIC50: 600nMAssay Description:Inhibition of CypD (unknown origin) PPIase activity using N-Suc-AAPF-p-nitroanilide as substrate preincubated with enzyme for 10 mins followed by chy...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM140005(US8901295, F684)
Affinity DataIC50: 640nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM140008(US8901295, F716)
Affinity DataIC50: 660nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516098(CHEMBL4547673)
Affinity DataIC50: 735nMAssay Description:Displacement of fluorescein labelled cyclosporine A derivative from human recombinant CypD (30 to 207 residues) expressed in Escherichia coli cells i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM140004(US8901295, F680)
Affinity DataIC50: 1.10E+3nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM140007(US8901295, F714)
Affinity DataIC50: 1.10E+3nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516080(CHEMBL4464178)
Affinity DataIC50: 1.35E+3nMAssay Description:Displacement of fluorescein labelled cyclosporine A derivative from human recombinant CypD (30 to 207 residues) expressed in Escherichia coli cells i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM140002(US8901295, F671)
Affinity DataIC50: 1.40E+3nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50169545(CHEMBL3805631)
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of human recombinant cyclophilin D using Suc-AAPF-MCA as substrate preincubated for 1 hr followed by substrate addition measured per milli...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516082(CHEMBL4464825)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of CypD (unknown origin) PPIase activity using N-Suc-AAPF-p-nitroanilide as substrate preincubated with enzyme for 10 mins followed by chy...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516095(CHEMBL4451136)
Affinity DataIC50: 1.70E+3nMAssay Description:Displacement of fluorescein labelled cyclosporine A derivative from human recombinant CypD (30 to 207 residues) expressed in Escherichia coli cells i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516084(CHEMBL4520315)
Affinity DataIC50: 1.70E+3nMAssay Description:Displacement of fluorescein labelled cyclosporine A derivative from human recombinant CypD (30 to 207 residues) expressed in Escherichia coli cells i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516082(CHEMBL4464825)
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of fluorescein labelled cyclosporine A derivative from human recombinant CypD (30 to 207 residues) expressed in Escherichia coli cells i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50381013(CHEMBL2017129)
Affinity DataIC50: 2.42E+3nMAssay Description:Inhibition of CypD (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516087(CHEMBL4471175)
Affinity DataIC50: 2.80E+3nMAssay Description:Displacement of fluorescein labelled cyclosporine A derivative from human recombinant CypD (30 to 207 residues) expressed in Escherichia coli cells i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM140006(US8901295, F712)
Affinity DataIC50: 3.00E+3nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516096(CHEMBL4540033)
Affinity DataIC50: 3.50E+3nMAssay Description:Displacement of fluorescein labelled cyclosporine A derivative from human recombinant CypD (30 to 207 residues) expressed in Escherichia coli cells i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516094(CHEMBL4453162)
Affinity DataIC50: 3.60E+3nMAssay Description:Displacement of fluorescein labelled cyclosporine A derivative from human recombinant CypD (30 to 207 residues) expressed in Escherichia coli cells i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516090(CHEMBL4563478)
Affinity DataIC50: 4.10E+3nMAssay Description:Displacement of fluorescein labelled cyclosporine A derivative from human recombinant CypD (30 to 207 residues) expressed in Escherichia coli cells i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM140003(US8901295, F673)
Affinity DataIC50: 6.20E+3nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM139995(US8901295, F428)
Affinity DataIC50: 6.20E+3nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM92913(Aryl 1-indanylketone, 2)
Affinity DataIC50: 6.28E+3nMAssay Description:Inhibition of CypD (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516096(CHEMBL4540033)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of CypD (unknown origin) PPIase activity using N-Suc-AAPF-p-nitroanilide as substrate preincubated with enzyme for 10 mins followed by chy...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516093(CHEMBL4445439)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of fluorescein labelled cyclosporine A derivative from human recombinant CypD (30 to 207 residues) expressed in Escherichia coli cells i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM394270(US9975902, Example 1)
Affinity DataIC50: 1.00E+4nMAssay Description:The binding capacity of the compounds was measured using a competition Fluorescence-Polarisation based assay with fluorescine labelled cyclosporin.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetPeptidyl-prolyl cis-trans isomerase D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM394274(US9975902, Example 4)
Affinity DataIC50: 1.00E+4nMAssay Description:The binding capacity of the compounds was measured using a competition Fluorescence-Polarisation based assay with fluorescine labelled cyclosporin.More data for this Ligand-Target Pair
In DepthDetails
US Patent

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