Report error Found 332 Enz. Inhib. hit(s) with Target = 'Pancreatic triacylglycerol lipase'
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate after 20 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of porcine pancreatic lipase using p-NPB as substrate pretreated for 15 mins followed by substrate addition measured after 15 mins by spec...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of porcine pancreatic lipase preincubated for 10 mins followed by 4-MUO addition and measured at 60 sec interval for 40 mins by multi plat...More data for this Ligand-Target Pair
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human PL expressed in HEK293F cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by s...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate after 20 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate after 20 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of porcine pancreatic lipaseMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate after 20 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate after 20 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate after 20 minsMore data for this Ligand-Target Pair
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of pancreatic lipase (unknown origin) by spectrophotometeric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate after 20 minsMore data for this Ligand-Target Pair
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 80.7nMAssay Description:Inhibition of pancreatic lipase assessed as umoles of oleic acic released per millimiter of triolein per hourMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of porcine pancreatic lipase using trioleate as substrate assessed as inhibition of substrate hydrolysis measured for 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of porcine pancreatic lipase measured after 40 mins by spectrophotocolorimetric enzymatic assayMore data for this Ligand-Target Pair
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of human pancreatic lipase using emulsified olive oil as substrate pretreated with substrate for 5 mins followed by enzyme addition and me...More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of porcine pancreatic lipase using micellar solution of triolein as substrate preincubated for 5 mins before substrate addition measured a...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenylbutyrate as substrate assessed as formation of p-nitrophenol preincubated for 15 mins foll...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenylbutyrate as substrate preincubated for 15 mins prior substrate addition measured after 15 ...More data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of porcine pancreatic lipase pre-incubated for 15 mins before p-nitrophenylbutyrate substrate addition by microplate reader based methodMore data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibition of porcine pancreatic lipase preincubated for 10 mins followed by 4-MUO addition and measured at 60 sec interval for 40 mins by multi plat...More data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Inhibition of porcine pancreatic lipase using triolein as substrate measured after 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of porcine pancreatic lipase using pNPB as substrate measured after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Inhibition of Pancreatic lipase (unknown origin) using 4-MUO as fluorescent substrate preincubated for 3 mins followed by substrate addition measured...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate pretreated for 15 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
Affinity DataIC50: 570nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
Affinity DataIC50: 580nMAssay Description:Inhibition of porcine pancreatic lipase preincubated for 10 mins followed by 4-MUO addition and measured at 60 sec interval for 40 mins by multi plat...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMpH: 6.8Assay Description:Particularly, pancreatic lipase inhibiting activity was measured by the conventional method known to those in the art (Kim, J. H.; Kim, H. J.; Park, ...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of pig pancreatic lipase assessed as p-NPB hydrolysis by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of pig pancreatic lipase assessed as hydrolysis of p-nitrophenylbutyrate to p-nitrophenolMore data for this Ligand-Target Pair
Affinity DataIC50: 680nMAssay Description:Inhibition of porcine pancreatic lipase preincubated for 10 mins followed by 4-MUO addition and measured at 60 sec interval for 40 mins by multi plat...More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
Affinity DataIC50: 710nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate pretreated for 15 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 760nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
Affinity DataIC50: 770nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate pretreated for 15 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 780nMAssay Description:Inhibition of PTL (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate pretreated for 15 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate pretreated for 15 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 806nMAssay Description:Compound was tested for inhibition of porcine pancreatic lipaseMore data for this Ligand-Target Pair
Affinity DataIC50: 830nMAssay Description:Inhibition of porcine pancreatic lipase preincubated for 10 mins followed by 4-MUO addition and measured at 60 sec interval for 40 mins by multi plat...More data for this Ligand-Target Pair
Affinity DataIC50: 840nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate pretreated for 15 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 850nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate assessed as formation of p-nitrophenol preincubated for 10 mins fol...More data for this Ligand-Target Pair
Affinity DataIC50: 850nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate pretreated for 15 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 910nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate pretreated for 15 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
