Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-9'
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50408547(CHEMBL135684)
Affinity DataKd:  0.0450nMAssay Description:The compound was tested for the inhibition of binding of [3H]epibatidine to central nicotinic acetylcholine receptor (nAChR) in rat brain.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50408546(CHEMBL335204)
Affinity DataKd:  13.6nMAssay Description:The compound was tested for the inhibition of binding of [3H]epibatidine to central nicotinic acetylcholine receptor (nAChR) in rat brain.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50408545(CHEMBL135897)
Affinity DataKd:  0.0270nMAssay Description:The compound was tested for the inhibition of binding of [3H]epibatidine to central nicotinic acetylcholine receptor (nAChR) in rat brain.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50408544(CHEMBL134341)
Affinity DataKd:  0.0270nMAssay Description:The compound was tested for the inhibition of binding of [3H]epibatidine to central nicotinic acetylcholine receptor (nAChR) in rat brain.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKd:  5nMAssay Description:The compound was tested for the inhibition of binding of [3H]epibatidine to central nicotinic acetylcholine receptor (nAChR) in rat brain.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50408543(CHEMBL336118)
Affinity DataKd:  0.0370nMAssay Description:The compound was tested for the inhibition of binding of [3H]epibatidine to central nicotinic acetylcholine receptor (nAChR) in rat brain.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50408542(CHEMBL337276)
Affinity DataKd:  0.0360nMAssay Description:The compound was tested for the inhibition of binding of [3H]epibatidine to central nicotinic acetylcholine receptor (nAChR) in rat brain.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50408541(CHEMBL134418)
Affinity DataKd:  0.0280nMAssay Description:The compound was tested for the inhibition of binding of [3H]epibatidine to central nicotinic acetylcholine receptor (nAChR) in rat brain.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataIC50: 2.40nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor by the displacement of [3H]-nicotine from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50077117(4-[2-(1-Methyl-pyrrolidin-2-yl)-ethylsulfanyl]-phe...)
Affinity DataIC50: 110nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor by the displacement of [3H]-nicotine from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170593((3S)-3-[(2S)-2-[(2R)-2-[(2R)-2-(2-aminoacetamido)-...)
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha9; Range is 100-200 nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50079884(2-(3-Pentyl-3H-diazirin-3-yl)-ethanol | CHEMBL1118...)
Affinity DataIC50: 3.30E+4nMAssay Description:The compound was tested for inhibitory potency against Nicotinic acetylcholine receptor in Rat muscle.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50100712(IPH | Epibatidine-I,(+/-) | CHEMBL54586 | 2-(6-Iod...)
Affinity DataKi:  6.5nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataKi:  7.5nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50107863((1S,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...)
Affinity DataKi:  190nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50049750(CHEMBL59986 | (S)-3-(azetidin-2-ylmethoxy)pyridine...)
Affinity DataKi:  320nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50004108((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50066789(A-85380,5-Iodo | CHEMBL123433 | A-85380-I | 3-((S)...)
Affinity DataKi:  1.40E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM86694(N'-(3-Chloro-4-morpholinophenyl)-N-hydroxyform...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed