Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-9'
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50408544(CHEMBL134341)
Affinity DataKd:  0.0270nMAssay Description:The compound was tested for the inhibition of binding of [3H]epibatidine to central nicotinic acetylcholine receptor (nAChR) in rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50408545(CHEMBL135897)
Affinity DataKd:  0.0270nMAssay Description:The compound was tested for the inhibition of binding of [3H]epibatidine to central nicotinic acetylcholine receptor (nAChR) in rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50408541(CHEMBL134418)
Affinity DataKd:  0.0280nMAssay Description:The compound was tested for the inhibition of binding of [3H]epibatidine to central nicotinic acetylcholine receptor (nAChR) in rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50408542(CHEMBL337276)
Affinity DataKd:  0.0360nMAssay Description:The compound was tested for the inhibition of binding of [3H]epibatidine to central nicotinic acetylcholine receptor (nAChR) in rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50408543(CHEMBL336118)
Affinity DataKd:  0.0370nMAssay Description:The compound was tested for the inhibition of binding of [3H]epibatidine to central nicotinic acetylcholine receptor (nAChR) in rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50408547(CHEMBL135684)
Affinity DataKd:  0.0450nMAssay Description:The compound was tested for the inhibition of binding of [3H]epibatidine to central nicotinic acetylcholine receptor (nAChR) in rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataIC50: 2.40nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor by the displacement of [3H]-nicotine from rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKd:  5nMAssay Description:The compound was tested for the inhibition of binding of [3H]epibatidine to central nicotinic acetylcholine receptor (nAChR) in rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50100712(IPH | Epibatidine-I,(+/-) | CHEMBL54586 | 2-(6-Iod...)
Affinity DataKi:  6.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataKi:  7.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50408546(CHEMBL335204)
Affinity DataKd:  13.6nMAssay Description:The compound was tested for the inhibition of binding of [3H]epibatidine to central nicotinic acetylcholine receptor (nAChR) in rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50077117(4-[2-(1-Methyl-pyrrolidin-2-yl)-ethylsulfanyl]-phe...)
Affinity DataIC50: 110nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor by the displacement of [3H]-nicotine from rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50107863((1S,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...)
Affinity DataKi:  190nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170593((3S)-3-[(2S)-2-[(2R)-2-[(2R)-2-(2-aminoacetamido)-...)
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha9; Range is 100-200 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50636720(CHEMBL5558610)
Affinity DataEC50:  230nMAssay Description:Agonist activity at human alpha9 nAChR expressed as xenopus laevis oocytes assessed as increase in receptor desensitization measured after 120 secs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50049750(CHEMBL59986 | (S)-3-(azetidin-2-ylmethoxy)pyridine...)
Affinity DataKi:  320nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50636728(CHEMBL3747105)
Affinity DataEC50:  368nMAssay Description:Agonist activity at alpha9 nAChR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50636722(CHEMBL5559353)
Affinity DataEC50:  380nMAssay Description:Agonist activity at human alpha9 nAChR expressed as xenopus laevis oocytes assessed as increase in receptor desensitization measured after 120 secs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50636718(CHEMBL5555218)
Affinity DataEC50:  510nMAssay Description:Agonist activity at human alpha9 nAChR expressed as xenopus laevis oocytes assessed as increase in receptor desensitization measured after 120 secs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50636727(CHEMBL5556786)
Affinity DataEC50:  660nMAssay Description:Agonist activity at alpha9 nAChR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50004108((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50636726(CHEMBL5561901)
Affinity DataEC50:  1.12E+3nMAssay Description:Partial agonist activity at human alpha9 nAChR expressed as xenopus laevis oocytes assessed as increase in receptor desensitization measured after 12...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50636714(CHEMBL3745917)
Affinity DataEC50:  1.15E+3nMAssay Description:Agonist activity at human alpha9 nAChR expressed as xenopus laevis oocytes assessed as increase in receptor desensitization measured after 120 secs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50636717(CHEMBL5559072)
Affinity DataEC50:  1.28E+3nMAssay Description:Agonist activity at human alpha9 nAChR expressed as xenopus laevis oocytes assessed as increase in receptor desensitization measured after 120 secs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50066789(A-85380,5-Iodo | CHEMBL123433 | A-85380-I | 3-((S)...)
Affinity DataKi:  1.40E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50636723(CHEMBL5560849)
Affinity DataEC50:  1.49E+3nMAssay Description:Agonist activity at human alpha9 nAChR expressed as xenopus laevis oocytes assessed as increase in receptor desensitization measured after 120 secs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50636719(CHEMBL5517963)
Affinity DataEC50:  1.63E+3nMAssay Description:Agonist activity at human alpha9 nAChR expressed as xenopus laevis oocytes assessed as increase in receptor desensitization measured after 120 secs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50636721(CHEMBL5561644)
Affinity DataEC50:  2.27E+3nMAssay Description:Agonist activity at human alpha9 nAChR expressed as xenopus laevis oocytes assessed as increase in receptor desensitization measured after 120 secs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50636725(CHEMBL5557858)
Affinity DataEC50:  7.00E+3nMAssay Description:Partial agonist activity at human alpha9 nAChR expressed as xenopus laevis oocytes assessed as increase in receptor desensitization measured after 12...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50636715(CHEMBL5568229)
Affinity DataEC50:  9.00E+3nMAssay Description:Agonist activity at human alpha9 nAChR expressed as xenopus laevis oocytes assessed as increase in receptor desensitization measured after 120 secs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50638386(CHEMBL5549960)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human alpha9 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM86694(N'-(3-Chloro-4-morpholinophenyl)-N-hydroxyform...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50636716(CHEMBL5532397)
Affinity DataEC50:  1.80E+4nMAssay Description:Agonist activity at human alpha9 nAChR expressed as xenopus laevis oocytes assessed as increase in receptor desensitization measured after 120 secs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM42410(2-acetyloxyethyl(trimethyl)azanium;bromide | MLS00...)
Affinity DataEC50:  2.60E+4nMAssay Description:Agonist activity at human alpha9 nAChR expressed as xenopus laevis oocytes assessed as increase in receptor desensitization measured after 120 secs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50079884(2-(3-Pentyl-3H-diazirin-3-yl)-ethanol | CHEMBL1118...)
Affinity DataIC50: 3.30E+4nMAssay Description:The compound was tested for inhibitory potency against Nicotinic acetylcholine receptor in Rat muscle.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-9(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50636724(CHEMBL5542521)
Affinity DataEC50:  4.50E+4nMAssay Description:Partial agonist activity at human alpha9 nAChR expressed as xenopus laevis oocytes assessed as increase in receptor desensitization measured after 12...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed