Compile Data Set for Download or QSAR
Report error Found 79 Enz. Inhib. hit(s) with Target = 'Neuroepithelial cell-transforming 1'
TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337910(CHEMBL1684057 | 1-(1-(3,4-dichlorophenyl)cyclohexy...)
Affinity DataIC50: 2.20nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337912(N-methyl-1-(1-(naphthalen-2-yl)cyclohexyl)ethanami...)
Affinity DataIC50: 2.30nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433673(US10562878, Compound 261 | US10562878, Compound 25...)
Affinity DataIC50: 2.40nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433764(US10562878, Compound 276 | US10562878, Compound 27...)
Affinity DataIC50: 2.70nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337831(N,N-dimethyl-1-(1-(naphthalen-1-yl)cyclohexyl)meth...)
Affinity DataIC50: 2.90nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337912(N-methyl-1-(1-(naphthalen-2-yl)cyclohexyl)ethanami...)
Affinity DataIC50: 3.60nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337910(CHEMBL1684057 | 1-(1-(3,4-dichlorophenyl)cyclohexy...)
Affinity DataIC50: 5.10nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337829(1-(1-(3,4-dichlorophenyl)cyclohexyl)-N,N-dimethylm...)
Affinity DataIC50: 6nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433682(US10562878, Compound 263 | US10562878, Compound 28...)
Affinity DataIC50: 11nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337818(N-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)-N-eth...)
Affinity DataIC50: 15nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433764(US10562878, Compound 276 | US10562878, Compound 27...)
Affinity DataIC50: 17nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337838(1-(1-(3,4-dichlorophenyl)cyclohexyl)-N-methylmetha...)
Affinity DataIC50: 20nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337912(N-methyl-1-(1-(naphthalen-2-yl)cyclohexyl)ethanami...)
Affinity DataIC50: 33nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337910(CHEMBL1684057 | 1-(1-(3,4-dichlorophenyl)cyclohexy...)
Affinity DataIC50: 44nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337910(CHEMBL1684057 | 1-(1-(3,4-dichlorophenyl)cyclohexy...)
Affinity DataIC50: 74nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337912(N-methyl-1-(1-(naphthalen-2-yl)cyclohexyl)ethanami...)
Affinity DataIC50: 79nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433736(US10562878, Compound 163 E2 | US10562878, Compound...)
Affinity DataIC50: 81nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433681(US10562878, Compound 256)
Affinity DataIC50: 130nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337851((1-(3,4-dichlorophenyl)cyclohexyl)methanamine | CH...)
Affinity DataIC50: 150nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50149940(CHEMBL3770651 | US10562878, Compound 203)
Affinity DataIC50: 340nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433736(US10562878, Compound 163 E2 | US10562878, Compound...)
Affinity DataIC50: 370nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337821((1-(naphthalen-1-yl)cyclohexyl)methanamine | CHEMB...)
Affinity DataIC50: 480nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433736(US10562878, Compound 163 E2 | US10562878, Compound...)
Affinity DataIC50: 500nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433736(US10562878, Compound 163 E2 | US10562878, Compound...)
Affinity DataIC50: 720nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337820(N-methyl-1-(1-(naphthalen-1-yl)cyclohexyl)methanam...)
Affinity DataIC50: 740nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433736(US10562878, Compound 163 E2 | US10562878, Compound...)
Affinity DataIC50: 1.20E+3nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433736(US10562878, Compound 163 E2 | US10562878, Compound...)
Affinity DataIC50: 3.20E+3nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433736(US10562878, Compound 163 E2 | US10562878, Compound...)
Affinity DataIC50: 4.20E+3nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433736(US10562878, Compound 163 E2 | US10562878, Compound...)
Affinity DataIC50: 4.90E+3nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM364387(US9862679, Compound 2r | US10913711, Compound 2r |...)
Affinity DataKi: >100nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM364404(US9862679, Compound 4a | US10913711, Compound 4a |...)
Affinity DataKi:  982nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50199854(CHEMBL3952924 | US9862679, Compound 7a | US1091371...)
Affinity DataKi:  988nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50199800(CHEMBL3979590 | US9862679, Compound 9g | US1091371...)
Affinity DataKi:  1.43E+3nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50199713(CHEMBL3965237 | US9862679, Compound 7b | US1091371...)
Affinity DataKi:  1.89E+3nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50199795(CHEMBL3909363 | US9862679, Compound 9j | US1091371...)
Affinity DataKi:  1.95E+3nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50336890((+/-)-N-(2-(benzhydrylsulfinyl)ethyl)-3-phenylprop...)
Affinity DataKi:  2.35E+3nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM364411(US9862679, Compound 4i | US10913711, Compound 4i |...)
Affinity DataKi:  3.18E+3nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM364414(US9862679, Compound 5c | US10913711, Compound 5c |...)
Affinity DataKi:  3.28E+3nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50199792(CHEMBL3126735 | US9862679, Compound 4g | US1091371...)
Affinity DataKi:  3.85E+3nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM364409(US9862679, Compound 4f | US10913711, Compound 4f |...)
Affinity DataKi:  3.91E+3nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM364421(US9862679, Compound 8b | US10913711, Compound 8b)
Affinity DataKi:  4.28E+3nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM364419(US9862679, Compound 8a | US10913711, Compound 8a)
Affinity DataKi:  5.54E+3nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM364415(US9862679, Compound 5d | US10913711, Compound 5d |...)
Affinity DataKi:  5.80E+3nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM364405(US9862679, Compound 4b | US10913711, Compound 4b |...)
Affinity DataKi:  6.97E+3nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM364416(US9862679, Compound 5e | US10913711, Compound 5e |...)
Affinity DataKi:  7.58E+3nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM364389(US9862679, Compound 2t | US10913711, Compound 2t |...)
Affinity DataKi:  7.60E+3nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM364382(US9862679, Compound 2m | US10913711, Compound 2m |...)
Affinity DataKi:  7.62E+3nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM364394(US9862679, Compound 2y | US10913711, Compound 2y |...)
Affinity DataKi:  7.98E+3nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM364406(US9862679, Compound 4c | US10913711, Compound 4c |...)
Affinity DataKi:  8.58E+3nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM364377(US9862679, Compound 2h | US10913711, Compound 2h |...)
Affinity DataKi:  9.81E+3nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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