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Report error Found 43 Enz. Inhib. hit(s) with Target = 'NADPH oxidase 5'
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM34233(EBSELEN | 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...)
Affinity DataEC50:  700nMAssay Description:Inhibition of NOX5 (unknown origin) transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50206334(Diphenylene iodonium chloride | dibenziodolium chl...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human NOX5 expressed in HEK293 cells assessed as inhibition of ionomycin-induced hydrogen peroxide production pretreated for 15 mins fo...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM318940(US10173988, Compound inventive)
Affinity DataIC50: 570nMAssay Description:Inhibition of NOX5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50606914(CHEMBL5218591)
Affinity DataIC50: 570nMAssay Description:Inhibition of human NOX5More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50628589(CHEMBL4210329)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human NOX5 transfected in HEK cells assessed as PMA-induced hydrogen peroxide production pre-incubated for 10 mins and measured after 1...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50071058(CHEMBL301982 | cid_4274774 | (2R,4aS,6aS,12bR,14aS...)
Affinity DataIC50: 3.13E+3nMAssay Description:Inhibition of human NOX5 expressed in HEK293 cells assessed as inhibition of ionomycin-induced hydrogen peroxide production pretreated for 15 mins fo...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50497263(CHEMBL3347554)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of full length human NOX5 transfected in HEK cells assessed as inhibition of ionomycin-stimulated ROS generation by chemiluminescence assa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50497257(CHEMBL3347502)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of full length human NOX5 transfected in HEK cells assessed as inhibition of ionomycin-stimulated ROS generation by chemiluminescence assa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50497268(CHEMBL3347491)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of full length human NOX5 transfected in HEK cells assessed as inhibition of ionomycin-stimulated ROS generation by chemiluminescence assa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50497272(CHEMBL3347543)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of full length human NOX5 transfected in HEK cells assessed as inhibition of ionomycin-stimulated ROS generation by chemiluminescence assa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50497262(CHEMBL3347492)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of full length human NOX5 transfected in HEK cells assessed as inhibition of ionomycin-stimulated ROS generation by chemiluminescence assa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50497265(CHEMBL3347503)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of full length human NOX5 transfected in HEK cells assessed as inhibition of ionomycin-stimulated ROS generation by chemiluminescence assa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50497261(CHEMBL3347549)
Affinity DataIC50: 7.90E+4nMAssay Description:Inhibition of full length human NOX5 transfected in HEK cells assessed as inhibition of ionomycin-stimulated ROS generation by chemiluminescence assa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50630371(CHEMBL5410142)
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibition of NOX5 (unknown origin) transfected in HEK cells assessed as reduction in PMA/ionomycin-stimulated H2O2 production preincubated for 15 mi...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50630348(CHEMBL5419067)
Affinity DataIC50: 9.50E+4nMAssay Description:Inhibition of NOX5 (unknown origin) transfected in HEK cells assessed as reduction in PMA/ionomycin-stimulated H2O2 production preincubated for 15 mi...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50497260(CHEMBL3347567)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full length human NOX5 transfected in HEK cells assessed as inhibition of ionomycin-stimulated ROS generation by chemiluminescence assa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50497264(CHEMBL3347524)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full length human NOX5 transfected in HEK cells assessed as inhibition of ionomycin-stimulated ROS generation by chemiluminescence assa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50497273(CHEMBL3347583)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full length human NOX5 transfected in HEK cells assessed as inhibition of ionomycin-stimulated ROS generation by chemiluminescence assa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50497269(CHEMBL3347584)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full length human NOX5 transfected in HEK cells assessed as inhibition of ionomycin-stimulated ROS generation by chemiluminescence assa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50497271(CHEMBL3347550)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full length human NOX5 transfected in HEK cells assessed as inhibition of ionomycin-stimulated ROS generation by chemiluminescence assa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50497258(CHEMBL3347566)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full length human NOX5 transfected in HEK cells assessed as inhibition of ionomycin-stimulated ROS generation by chemiluminescence assa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50497259(CHEMBL3347542)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full length human NOX5 transfected in HEK cells assessed as inhibition of ionomycin-stimulated ROS generation by chemiluminescence assa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50497270(CHEMBL3347551)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full length human NOX5 transfected in HEK cells assessed as inhibition of ionomycin-stimulated ROS generation by chemiluminescence assa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50497267(CHEMBL3347501)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full length human NOX5 transfected in HEK cells assessed as inhibition of ionomycin-stimulated ROS generation by chemiluminescence assa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50497266(CHEMBL3347525)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full length human NOX5 transfected in HEK cells assessed as inhibition of ionomycin-stimulated ROS generation by chemiluminescence assa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50359525(CHEMBL1927146)
Affinity DataKi:  360nMAssay Description:Antagonist activity at human NOX5 assessed as inhibition of ROS production after 20 mins by cell-free amplex red assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50628591(Setanaxib | GKT-137831 | GKT-831 | SETANAXIB)
Affinity DataKi:  410nMAssay Description:Binding affinity to human NOX5 assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50359523(CHEMBL1927147)
Affinity DataKi:  414nMAssay Description:Antagonist activity at human NOX5 assessed as inhibition of ROS production after 20 mins by cell-free amplex red assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50359529(CHEMBL1927150)
Affinity DataKi:  475nMAssay Description:Antagonist activity at human NOX5 assessed as inhibition of ROS production after 20 mins by cell-free amplex red assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50359522(CHEMBL1927160)
Affinity DataKi:  490nMAssay Description:Antagonist activity at human NOX5 assessed as inhibition of ROS production after 20 mins by cell-free amplex red assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50359519(CHEMBL1927157)
Affinity DataKi:  543nMAssay Description:Antagonist activity at human NOX5 assessed as inhibition of ROS production after 20 mins by cell-free amplex red assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50359530(CHEMBL1927151)
Affinity DataKi:  585nMAssay Description:Antagonist activity at human NOX5 assessed as inhibition of ROS production after 20 mins by cell-free amplex red assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50359524(CHEMBL1927145)
Affinity DataKi:  590nMAssay Description:Antagonist activity at human NOX5 assessed as inhibition of ROS production after 20 mins by cell-free amplex red assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50359520(CHEMBL1927158)
Affinity DataKi:  610nMAssay Description:Antagonist activity at human NOX5 assessed as inhibition of ROS production after 20 mins by cell-free amplex red assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50359528(CHEMBL1927149)
Affinity DataKi:  615nMAssay Description:Antagonist activity at human NOX5 assessed as inhibition of ROS production after 20 mins by cell-free amplex red assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50359527(CHEMBL1927148)
Affinity DataKi:  670nMAssay Description:Antagonist activity at human NOX5 assessed as inhibition of ROS production after 20 mins by cell-free amplex red assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50359533(CHEMBL1927154)
Affinity DataKi:  690nMAssay Description:Antagonist activity at human NOX5 assessed as inhibition of ROS production after 20 mins by cell-free amplex red assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50359521(CHEMBL1927159)
Affinity DataKi:  690nMAssay Description:Antagonist activity at human NOX5 assessed as inhibition of ROS production after 20 mins by cell-free amplex red assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50359532(CHEMBL1927153)
Affinity DataKi:  730nMAssay Description:Antagonist activity at human NOX5 assessed as inhibition of ROS production after 20 mins by cell-free amplex red assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50359531(CHEMBL1927152)
Affinity DataKi:  740nMAssay Description:Antagonist activity at human NOX5 assessed as inhibition of ROS production after 20 mins by cell-free amplex red assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50359534(CHEMBL1927155)
Affinity DataKi:  955nMAssay Description:Antagonist activity at human NOX5 assessed as inhibition of ROS production after 20 mins by cell-free amplex red assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50359518(CHEMBL1927156)
Affinity DataKi:  1.15E+3nMAssay Description:Antagonist activity at human NOX5 assessed as inhibition of ROS production after 20 mins by cell-free amplex red assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50359526(CHEMBL1926690)
Affinity DataKi:  1.43E+3nMAssay Description:Antagonist activity at human NOX5 assessed as inhibition of ROS production after 20 mins by cell-free amplex red assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed