Report error Found 87 Enz. Inhib. hit(s) with Target = 'N6-adenosine-methyltransferase catalytic subunit'
Displayed 1 to 50 (of 87 total ) | Next | Last >>
Affinity DataKd: 1.40nMAssay Description:Binding affinity to METTL3 (unknown origin) by SPR methodMore data for this Ligand-Target Pair
Affinity DataKd: 4.80nMAssay Description:Binding affinity to METTL3 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 4.80nMAssay Description:Binding affinity to METTL3 (unknown origin) assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of METTL3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of METTL3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 7.90nMAssay Description:Inhibition of METTL3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 10nMAssay Description:Inhibition of full-length human recombinant METTL3 (369 to 580 residues) expressed in baculovirus expression system infected in Sf9 cells by fluoresc...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 10nMAssay Description:Inhibition of METTL3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 10nMAssay Description:Inhibition of METTL3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 10nMAssay Description:Inhibition of METTL3 (unknown origin) using 3' biotinylated RNA (UCUGGACUAAA) and 3H-SAM as a substrate preincubated for 5 mins followed by substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of METTL3 (unknown origin) using 3' biotinylated RNA (UCUGGACUAAA) and 3H-SAM as a substrate preincubated for 5 mins followed by substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of METTL3 (unknown origin) using 3' biotinylated RNA (UCUGGACUAAA) and 3H-SAM as a substrate preincubated for 5 mins followed by substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of full-length human recombinant METTL3 (369 to 580 residues) expressed in baculovirus expression system infected in Sf9 cells by fluoresc...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 10nMAssay Description:Inhibition of METTL3 (unknown origin) using 3' biotinylated RNA (UCUGGACUAAA) and 3H-SAM as a substrate preincubated for 5 mins followed by substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of METTL3 (unknown origin) using 3' biotinylated RNA (UCUGGACUAAA) and 3H-SAM as a substrate preincubated for 5 mins followed by substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of METTL3 (unknown origin) using 3' biotinylated RNA (UCUGGACUAAA) and 3H-SAM as a substrate preincubated for 5 mins followed by substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of METTL3 in human MOLM-13 cells assessed as reduction in m6A methylation levelMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of full length His-tagged METTL3 in baculovirus expression system (unknown origin) measured by mass spectrometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of full length His-tagged METTL3 (unknown origin) expressed in Sf9 cells by RapidFire mass spectrometry analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of METTL3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Affinity DataIC50: 89nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of METTL3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Affinity DataIC50: 440nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Affinity DataIC50: 590nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Affinity DataIC50: 790nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Affinity DataEC50: 850nMAssay Description:Thermal stabilization of endogenously expressing full length METTL3 in human MOLM-13 cells assessed as stabilized METTL3 incubated for at 54 degC by ...More data for this Ligand-Target Pair
Affinity DataIC50: 970nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of METTL3 in human MOLM-13 cells assessed as decrease in cellular m6A mRNA level incubated for 24 hrs by NanoDrop spectrophotometer based ...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of METTL3-mediated m6A methylation in human MOLM-3 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of METTL3-mediated m6A methylation in human MOLM-3 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of METTL3 in human MOLM-13 cells assessed as decrease in cellular m6A mRNA level incubated for 24 hrs by NanoDrop spectrophotometer based ...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of METTL3-mediated m6A methylation in human MOLM-3 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of METTL3 in human MOLM-13 cells assessed as decrease in cellular m6A mRNA level incubated for 24 hrs by NanoDrop spectrophotometer based ...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of METTL3-mediated m6A methylation in human MOLM-3 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of METTL3 in human MOLM-13 cells assessed as down regulation of m6A RNA level incubated for 72 hrs by Dot blot assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of METTL3 in human MOLM-13 cells assessed as down regulation of m6A RNA level incubated for 72 hrs by Dot blot assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of METTL3 in human MOLM-13 cells assessed as decrease in cellular m6A mRNA level incubated for 24 hrs by NanoDrop spectrophotometer based ...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of METTL3 in human MOLM-13 cells assessed as decrease in cellular m6A mRNA level incubated for 24 hrs by NanoDrop spectrophotometer based ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of METTL3 in human MOLM-13 cells assessed as decrease in cellular m6A mRNA level incubated for 24 hrs by NanoDrop spectrophotometer based ...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of METTL3 in human MOLM-13 cells assessed as decrease in cellular m6A mRNA level incubated for 24 hrs by NanoDrop spectrophotometer based ...More data for this Ligand-Target Pair
Ligand InfoSimilars




3D Structure (crystal)



























