Compile Data Set for Download or QSAR
Report error Found 363 Enz. Inhib. hit(s) with Target = 'N-glycosylase/DNA lyase'
TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50630974(CHEMBL5429494)
Affinity DataEC50:  780nMAssay Description:Activation of OGG1 (unknown origin) by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50630975(TCMDC-132084 | CHEMBL529145)
Affinity DataEC50:  5.00E+3nMAssay Description:Activation of OGG1 (unknown origin) by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50630976(CHEMBL5411882)
Affinity DataEC50:  4.60E+3nMAssay Description:Activation of OGG1 (unknown origin) by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50630977(CHEMBL5401642)
Affinity DataEC50:  5.10E+3nMAssay Description:Activation of OGG1 (unknown origin) by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50630978(CHEMBL5402302)
Affinity DataEC50:  4.10E+3nMAssay Description:Activation of OGG1 (unknown origin) by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670284(US11970474, Example 228)
Affinity DataIC50: 0.150nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670310(US11970474, Example 254)
Affinity DataIC50: 0.210nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670321(US11970474, Example 265)
Affinity DataIC50: 0.280nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670348(US11970474, Example 292)
Affinity DataIC50: 0.370nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670326(US11970474, Example 270)
Affinity DataIC50: 0.390nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670303(US11970474, Example 247)
Affinity DataIC50: 0.620nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670350(US11970474, Example 294)
Affinity DataIC50: 1.21nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670349(US11970474, Example 293)
Affinity DataIC50: 1.42nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670340(US11970474, Example 284)
Affinity DataIC50: 1.73nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670319(US11970474, Example 263)
Affinity DataIC50: 2.71nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670362(US11970474, Example 306)
Affinity DataIC50: 2.82nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670332(US11970474, Example 276)
Affinity DataIC50: 2.90nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670368(US11970474, Example 312)
Affinity DataIC50: 2.94nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670365(US11970474, Example 309)
Affinity DataIC50: 3.26nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670360(US11970474, Example 304)
Affinity DataIC50: 3.80nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670308(US11970474, Example 252)
Affinity DataIC50: 3.94nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670315(US11970474, Example 259)
Affinity DataIC50: 3.94nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670328(US11970474, Example 272)
Affinity DataIC50: 4.11nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670307(US11970474, Example 251)
Affinity DataIC50: 4.25nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670367(US11970474, Example 311)
Affinity DataIC50: 4.49nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670377(US11970474, Example 321)
Affinity DataIC50: 5.75nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670320(US11970474, Example 264)
Affinity DataIC50: 5.77nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670314(US11970474, Example 258)
Affinity DataIC50: 5.83nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670304(US11970474, Example 248)
Affinity DataIC50: 6.77nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670309(US11970474, Example 253)
Affinity DataIC50: 6.79nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670357(US11970474, Example 301)
Affinity DataIC50: 6.91nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670353(US11970474, Example 297)
Affinity DataIC50: 8.07nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670322(US11970474, Example 266)
Affinity DataIC50: 8.16nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670268(US11970474, Example 212)
Affinity DataIC50: 9.43nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670347(US11970474, Example 291)
Affinity DataIC50: 9.53nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670351(US11970474, Example 295)
Affinity DataIC50: 9.62nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670356(US11970474, Example 300)
Affinity DataIC50: 9.90nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670338(US11970474, Example 282)
Affinity DataIC50: 10.1nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670359(US11970474, Example 303)
Affinity DataIC50: 10.6nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670354(US11970474, Example 298)
Affinity DataIC50: 12nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670182(US11970474, Example 126)
Affinity DataIC50: 12nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670363(US11970474, Example 307)
Affinity DataIC50: 12.5nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670339(US11970474, Example 283)
Affinity DataIC50: 14nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670296(US11970474, Example 240)
Affinity DataIC50: 15.3nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670262(US11970474, Example 206)
Affinity DataIC50: 15.4nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670358(US11970474, Example 302)
Affinity DataIC50: 16.4nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670250(US11970474, Example 194)
Affinity DataIC50: 17.2nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670329(US11970474, Example 273)
Affinity DataIC50: 17.5nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670283(US11970474, Example 227)
Affinity DataIC50: 17.9nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-glycosylase/DNA lyase(Human)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM670342(US11970474, Example 286)
Affinity DataIC50: 18.1nMAssay Description:OGG1 activity is assayed by measuring the increase in fluorescence from a duplex oligonucleotide containing an OGG1 substrate and a fluorophore in cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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