Compile Data Set for Download or QSAR
Report error Found 903 Enz. Inhib. hit(s) with Target = 'Monocarboxylate transporter 4'
TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50349537(CHEMBL5434099)
Affinity DataEC50:  5nMAssay Description:Compound was evaluated for Adrenergic activity against Alpha-2 adrenergic receptor in human plateletsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50349534(CHEMBL5419465)
Affinity DataIC50: 0.230nMAssay Description:Inhibition of Escherichia coli FabH expressed in Escherichia coli DH10B cells assessed as incorporation of 3H signal in the product after 25 mins by ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50349535(CHEMBL5399511)
Affinity DataIC50: 0.290nMAssay Description:Inhibition of Escherichia coli FabH expressed in Escherichia coli DH10B cells assessed as incorporation of 3H signal in the product after 25 mins by ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356873(US10214492, Example 223 | US11292767, Example 223)
Affinity DataIC50: 0.300nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356917(US10214492, Example 268 | US11292767, Example 268)
Affinity DataIC50: 0.300nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356873(US10214492, Example 223 | US11292767, Example 223)
Affinity DataIC50: 0.300nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356917(US10214492, Example 268 | US11292767, Example 268)
Affinity DataIC50: 0.300nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356917(US10214492, Example 268 | US11292767, Example 268)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of MCT4 in human MDA-MB-231 cells by BCECF-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356790(US10214492, Example 155 | US11292767, Example 155)
Affinity DataIC50: 0.320nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356790(US10214492, Example 155 | US11292767, Example 155)
Affinity DataIC50: 0.320nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356906(US10214492, Example 257 | US11292767, Example 257)
Affinity DataIC50: 0.350nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356913(US10214492, Example 264)
Affinity DataIC50: 0.350nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356906(US10214492, Example 257 | US11292767, Example 257)
Affinity DataIC50: 0.350nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM546758((2R)-2-([5-(3,5-Dimethoxyphenyl)-1- [(2-ethoxyphen...)
Affinity DataIC50: 0.350nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356915(US10214492, Example 266 | US11292767, Example 266)
Affinity DataIC50: 0.360nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356915(US10214492, Example 266 | US11292767, Example 266)
Affinity DataIC50: 0.360nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356915(US10214492, Example 266 | US11292767, Example 266)
Affinity DataIC50: 0.360nMAssay Description:Inhibition of MCT4 in human MDA-MB-231 cells by BCECF-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50349533(CHEMBL5422048)
Affinity DataIC50: 0.380nMAssay Description:Inhibition of Escherichia coli FabH expressed in Escherichia coli DH10B cells assessed as incorporation of 3H signal in the product after 25 mins by ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356870(US10214492, Example 220 | US11292767, Example 220)
Affinity DataIC50: 0.540nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356870(US10214492, Example 220 | US11292767, Example 220)
Affinity DataIC50: 0.540nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356916(US10214492, Example 267 | US11292767, Example 267)
Affinity DataIC50: 0.570nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356916(US10214492, Example 267 | US11292767, Example 267)
Affinity DataIC50: 0.570nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356916(US10214492, Example 267 | US11292767, Example 267)
Affinity DataIC50: 0.570nMAssay Description:Inhibition of MCT4 in human MDA-MB-231 cells by BCECF-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356805(US10214492, Example 167 | US11292767, Example 167)
Affinity DataIC50: 0.590nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356811(US10214492, Example 172 | US11292767, Example 172)
Affinity DataIC50: 0.590nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356805(US10214492, Example 167 | US11292767, Example 167)
Affinity DataIC50: 0.590nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356811(US10214492, Example 172 | US11292767, Example 172)
Affinity DataIC50: 0.590nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356909(US10214492, Example 260 | US11292767, Example 260)
Affinity DataIC50: 0.830nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356909(US10214492, Example 260 | US11292767, Example 260)
Affinity DataIC50: 0.830nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50349536(CHEMBL5425432)
Affinity DataIC50: 0.910nMAssay Description:Inhibition of Escherichia coli FabH expressed in Escherichia coli DH10B cells assessed as incorporation of 3H signal in the product after 25 mins by ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM345281(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- isobutoxyphe...)
Affinity DataIC50: 1nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM345281(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- isobutoxyphe...)
Affinity DataIC50: 1nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356918(US10214492, Example 269 | US11292767, Example 269)
Affinity DataIC50: 1nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM345281(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- isobutoxyphe...)
Affinity DataIC50: 1nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356918(US10214492, Example 269 | US11292767, Example 269)
Affinity DataIC50: 1nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM345281(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- isobutoxyphe...)
Affinity DataIC50: 1nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50606663(CHEMBL5219543)
Affinity DataIC50: 1nMAssay Description:Inhibition of MCT4 in human NCI-H358 cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50606664(CHEMBL1616099)
Affinity DataIC50: 1nMAssay Description:Inhibition of MCT4 in human NCI-H358 cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50606665(SYROSINGOPINE | Syrosingopine | Isotense | Londomi...)
Affinity DataIC50: 1nMAssay Description:Inhibition of MCT4 in human NCI-H358 cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50606663(CHEMBL5219543)
Affinity DataIC50: 1nMAssay Description:Inhibition of MCT4 in human MDA-MB-231 cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50606664(CHEMBL1616099)
Affinity DataIC50: 1nMAssay Description:Inhibition of MCT4 in human MDA-MB-231 cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50606665(SYROSINGOPINE | Syrosingopine | Isotense | Londomi...)
Affinity DataIC50: 1nMAssay Description:Inhibition of MCT4 in human MDA-MB-231 cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM345298(2-[[1-[(2-Chlorophenyl)methyl]-5-[3- (cyclopentyl...)
Affinity DataIC50: 1.10nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM345298(2-[[1-[(2-Chlorophenyl)methyl]-5-[3- (cyclopentyl...)
Affinity DataIC50: 1.10nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM345298(2-[[1-[(2-Chlorophenyl)methyl]-5-[3- (cyclopentyl...)
Affinity DataIC50: 1.10nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM345298(2-[[1-[(2-Chlorophenyl)methyl]-5-[3- (cyclopentyl...)
Affinity DataIC50: 1.10nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356764(US10214492, Example 128 | US11292767, Example 128)
Affinity DataIC50: 1.20nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356764(US10214492, Example 128 | US11292767, Example 128)
Affinity DataIC50: 1.20nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356832(US10214492, Example 183 | US11292767, Example 183)
Affinity DataIC50: 1.30nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM356899(US10214492, Example 250)
Affinity DataIC50: 1.30nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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