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Report error Found 764 Enz. Inhib. hit(s) with Target = 'Monocarboxylate transporter 1'
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50103571(CHEMBL3335793)
Affinity DataKd:  1.60nMAssay Description:Binding affinity to MCT1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180637(CHEMBL3818005)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180638(CHEMBL3818980)
Affinity DataEC50:  55nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180639(CHEMBL3818923)
Affinity DataEC50:  60nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180640(CHEMBL3819278)
Affinity DataEC50:  520nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180641(CHEMBL3818095)
Affinity DataEC50:  24nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180642(CHEMBL3818476)
Affinity DataEC50:  420nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180643(CHEMBL3818311)
Affinity DataEC50:  0.800nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180644(CHEMBL3818991)
Affinity DataEC50:  500nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180645(CHEMBL3817951)
Affinity DataEC50:  0.800nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180646(CHEMBL3819279)
Affinity DataEC50:  100nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180647(CHEMBL3818777)
Affinity DataEC50:  0.160nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180648(CHEMBL3818150)
Affinity DataEC50:  0.800nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180649(CHEMBL3818851)
Affinity DataEC50:  4nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180650(CHEMBL3817902)
Affinity DataEC50:  11nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM22000(7-[(3-hydroxypropyl)sulfanyl]-2-methyl-4-(2-methyl...)
Affinity DataEC50:  5nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50180651(CHEMBL3819158)
Affinity DataEC50:  690nMAssay Description:Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Rat)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM50092072(CHEMBL3582419 | US9296728, 14)
Affinity DataIC50: 7.60nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 1(Rat)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM50092069(CHEMBL3582422 | US9296728, 20)
Affinity DataIC50: 8nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 1(Rat)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM50092069(CHEMBL3582422 | US9296728, 20)
Affinity DataIC50: 8nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50092069(CHEMBL3582422 | US9296728, 20)
Affinity DataIC50: 8nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMonocarboxylate transporter 1(Rat)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM50092072(CHEMBL3582419 | US9296728, 14)
Affinity DataIC50: 9nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50092072(CHEMBL3582419 | US9296728, 14)
Affinity DataIC50: 9nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMonocarboxylate transporter 1(Rat)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM50092073(CHEMBL3582418 | US9296728, 13)
Affinity DataIC50: 9.5nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 1(Rat)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM50092058(CHEMBL3582408)
Affinity DataIC50: 10nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Rat)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM50092068(CHEMBL3582423)
Affinity DataIC50: 11nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Rat)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM50092071(CHEMBL3582420 | US9296728, 18)
Affinity DataIC50: 11nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50092071(CHEMBL3582420 | US9296728, 18)
Affinity DataIC50: 11nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMonocarboxylate transporter 1(Rat)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM50092073(CHEMBL3582418 | US9296728, 13)
Affinity DataIC50: 12nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Rat)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM50608638(CHEMBL4303684 | US20240091210, Compound UK5099)
Affinity DataIC50: 13nMAssay Description:Inhibition of MCT1 in rat Brain-like endothelial cells incubated for 15 mins in presence of [14C]lactic acid by scintillation counter assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMonocarboxylate transporter 1(Rat)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM50092071(CHEMBL3582420 | US9296728, 18)
Affinity DataIC50: 15nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 1(Rat)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM214697(US9296728, 19)
Affinity DataIC50: 19nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 1(Rat)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM50092070(CHEMBL3582421 | US9296728, 15)
Affinity DataIC50: 23nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 1(Rat)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM50092067(CHEMBL3582424 | US9296728, 16)
Affinity DataIC50: 25nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 1(Rat)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM50092065(CHEMBL3582426)
Affinity DataIC50: 25nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50608633(CHEMBL3582501)
Affinity DataIC50: 25nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMonocarboxylate transporter 1(Rat)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM50092057(CHEMBL3582409 | US9296728, 4)
Affinity DataIC50: 26nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 1(Rat)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM50092067(CHEMBL3582424 | US9296728, 16)
Affinity DataIC50: 29nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Rat)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM50092076(CHEMBL3582415)
Affinity DataIC50: 30nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Rat)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM50092057(CHEMBL3582409 | US9296728, 4)
Affinity DataIC50: 30nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Rat)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM50092070(CHEMBL3582421 | US9296728, 15)
Affinity DataIC50: 34nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50092070(CHEMBL3582421 | US9296728, 15)
Affinity DataIC50: 34nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM214697(US9296728, 19)
Affinity DataIC50: 37nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMonocarboxylate transporter 1(Rat)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM214695(US9296728, 10)
Affinity DataIC50: 43nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 1(Rat)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM214702(US9296728, 25)
Affinity DataIC50: 48nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 1(Rat)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM50092066(CHEMBL3582425)
Affinity DataIC50: 48nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM214698(US9296728, 21)
Affinity DataIC50: 48nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM345287(2-[[1-[(2-Chlorophenyl)methyl]-5-[3- (cyclopropyl...)
Affinity DataIC50: 54.5nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM356766(US10214492, Example 130)
Affinity DataIC50: 55nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMonocarboxylate transporter 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM546629(2-([1-[(2-Chlorophenyl)methyl]-5-(4- cyclopropoxyt...)
Affinity DataIC50: 55nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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