Compile Data Set for Download or QSAR
Report error Found 620 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 12'
LigandPNGBDBM31085(cid_11409972 | 1-[4-[(4-ethylpiperazin-1-yl)methyl...)
Affinity DataKd:  2.50E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM25118(4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataKd:  2.10E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM31090((E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-etho...)
Affinity DataKd:  2.60E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)
Affinity DataKd:  5.20E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  560nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM31096(CHEMBL290084 | Staurosporine | cid_451705 | US2024...)
Affinity DataKd:  1.50E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  100nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM13534(VX680 | N-[4-[[4-(4-methylpiperazino)-6-[(5-methyl...)
Affinity DataKd:  190nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  1.50E+3nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  840nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataKd:  140nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM6568(PD-173955 | CHEMBL386051 | 6-(2,6-dichlorophenyl)-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM26300(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50355496(CHEMBL1908397)
Affinity DataKd:  67nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM25121(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM60665(US9145414, R406 | US9212178, R406 | BDBM50249542)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataKd:  170nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24773(N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyr...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50355495(CHEMBL1908391)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50237710(AMN 107 | AMN107 | 4-methyl-N-[3-(4-methyl-1H-imid...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM25045(CHEMBL538346 | mTOR Inhibitor, PI103 | PI-103 | 3-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  560nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50300690(CHEMBL576982 | N-(5-tert-Butyl-isoxazol-3-yl)-N'-{...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM15244(cid_3038525 | 5-(2,6-dichlorophenyl)-2-[(2,4-diflu...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM21079(1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM25628(2-{4-[(1Z)-1-(hydroxyimino)-2,3-dihydro-1H-inden-5...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM31093(cid_11712649 | 4-[[7-[2,6-bis(fluoranyl)phenyl]-9-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM60589(6-{[6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50309910(N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17055((9S)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydr...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataKd:  6.30E+3nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50128285(3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-pyridin-2-ylmet...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM31088(1-methyl-5-[[2-[5-(trifluoromethyl)-1H-imidazol-2-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM482158(TAE684 | BDBM50242742)
Affinity DataKd:  42nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM13535(N-(4-isopropoxyphenyl)-4-[6-methoxy-7-(3-piperidin...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50355499(CHEMBL1908395 | CHEMBL1908842)
Affinity DataKd:  330nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM25117(AG-013736 | N-methyl-2-({3-[(E)-2-(pyridin-2-yl)et...)
Affinity DataKd:  1.70E+3nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM5445(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM25118(4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataKd:  2.10E+3nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50161957(CHEMBL180022 | N-(4-(3-chloro-4-(pyridin-2-ylmetho...)
Affinity DataKd:  370nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50355501(RUXOLITINIB PHOSPHATE | INCB-018424 | RUXOLITINIB ...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM25084(JMC504279 Compound 6 | 3-[2,4-diamino-6-(3-hydroxy...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 620 total ) | Next | Last >>
Jump to: