Compile Data Set for Download or QSAR
Report error Found 354 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 7'
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM5931(cid_3025986 | CHEMBL296468 | N-(5-{[(5-tert-butyl-...)
Affinity DataKd:  650nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31099(CHEMBL45741 | Flavopiridol | cid_24867231 | 2-(2-c...)
Affinity DataKd:  620nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)
Affinity DataKd:  520nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31096(CHEMBL290084 | Staurosporine | cid_451705 | US2024...)
Affinity DataKd:  1.60E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM81377(FIIN-1)
Affinity DataKd:  160nMAssay Description:In vitro kinase assay profiled against a panel of different kinase binding assay using Ambit kinomeScan technology. Biochemical IC50 values were det...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM81378(FRIN-1)
Affinity DataKd:  130nMAssay Description:In vitro kinase assay profiled against a panel of different kinase binding assay using Ambit kinomeScan technology. Biochemical IC50 values were det...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50337134(US9266890, IV-6 | Scaffold, B46 | CHEMBL1673046 | ...)
Affinity DataKd:  80nMAssay Description:In vitro biochemical assays were performed in parallel to determine the most potent tool compound.More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM209410(US9266890, I-20)
Affinity DataKd:  550nMAssay Description:In vitro Erk5 binding assay: Ambit Kd values in nanomolar. Kd values generated by Ambit binding assay over a concentration range of the compound.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM209414(US9266890, I-24)
Affinity DataKd:  320nMAssay Description:In vitro Erk5 binding assay: Ambit Kd values in nanomolar. Kd values generated by Ambit binding assay over a concentration range of the compound.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50337126(US9266890, IV-2 | CHEMBL1672987 | Scaffold, B19 | ...)
Affinity DataKd:  670nMAssay Description:In vitro Erk5 binding assay: Ambit Kd values in nanomolar. Kd values generated by Ambit binding assay over a concentration range of the compound.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50337127(US9266890, IV-1 | 2-(2-methoxy-4-(4-methylpiperazi...)
Affinity DataKd:  19nMAssay Description:In vitro Erk5 binding assay: Ambit Kd values in nanomolar. Kd values generated by Ambit binding assay over a concentration range of the compound.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50337128(US9266890, IV-7 | 2-((4-(4-hydroxypiperidin-1-yl)-...)
Affinity DataKd:  57nMAssay Description:In vitro Erk5 binding assay: Ambit Kd values in nanomolar. Kd values generated by Ambit binding assay over a concentration range of the compound.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50337134(US9266890, IV-6 | Scaffold, B46 | CHEMBL1673046 | ...)
Affinity DataKd:  80nMAssay Description:In vitro Erk5 binding assay: Ambit Kd values in nanomolar. Kd values generated by Ambit binding assay over a concentration range of the compound.More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM209448(US9266890, IV-8)
Affinity DataKd:  50nMAssay Description:In vitro Erk5 binding assay: Ambit Kd values in nanomolar. Kd values generated by Ambit binding assay over a concentration range of the compound.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to ERK5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to ERK5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataKd:  2.50E+3nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  1.60E+3nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  1.10E+3nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  1.60E+3nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50300690(CHEMBL576982 | N-(5-tert-Butyl-isoxazol-3-yl)-N'-{...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to ERK5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50326054(CHEMBL1240703)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to ERK5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM13535(N-(4-isopropoxyphenyl)-4-[6-methoxy-7-(3-piperidin...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to ERK5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to ERK5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to ERK5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM36409(CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50355494(CHEMBL1908396)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM15138(Biochemistry 469551 Compound 11 | 5-indazolyl pyri...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM32362(cid_11617559 | GW-2580 | 5-[[3-methoxy-4-[(4-metho...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM12621(2,4-Diamino-5-ketopyrimidine 39 | 5-[(2,3-difluoro...)
Affinity DataKd:  110nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM4851(cid_151194 | PTK787 | CHEMBL101253 | N-(4-chloroph...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31088(1-methyl-5-[[2-[5-(trifluoromethyl)-1H-imidazol-2-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM17055((9S)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydr...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM25045(CHEMBL538346 | mTOR Inhibitor, PI103 | PI-103 | 3-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM26474(GW-786034 | JMC514632 Compound 13 | 5-({4-[(2,3-di...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM6568(PD-173955 | CHEMBL386051 | 6-(2,6-dichlorophenyl)-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM25117(AG-013736 | N-methyl-2-({3-[(E)-2-(pyridin-2-yl)et...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM25919(N-(2-aminoethyl)-3,12-dimethyl-2,5,8-triazatricycl...)
Affinity DataKd:  620nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM13533(1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-m...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM482158(TAE684 | BDBM50242742)
Affinity DataKd:  48nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM25028(4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpipera...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50331096(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxy-7...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM60589(6-{[6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM60665(US9145414, R406 | US9212178, R406 | BDBM50249542)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataKd:  2.30E+3nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50355497(AZD-6244 | CHEMBL1614701)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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