Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2/3'
LigandPNGBDBM50056272((2S,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxy...)
Affinity DataEC50:  9.80nMAssay Description:Agonist activity at mGlu2/3 receptor in Sprague-Dawley rat forebrain assessed as inhibition of spontaneous Ca2+ oscillations in cortical neurons afte...More data for this Ligand-Target Pair
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PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50244219(CHEMBL4081453)
Affinity DataKi:  106nMAssay Description:Displacement of [3H]-LY459477 from mGlu2/3 receptor in Sprague-Dawley rat forebrain primary cortical membranes after 90 mins by liquid scintillation ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50056272((2S,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxy...)
Affinity DataKi:  476nMAssay Description:Displacement of [3H]-LY459477 from mGlu2/3 receptor in Sprague-Dawley rat forebrain primary cortical membranes after 90 mins by liquid scintillation ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)