Report error Found 168 Enz. Inhib. hit(s) with Target = 'Matrix protein 2'
Displayed 1 to 50 (of 168 total ) | Next | Last >>
Affinity DataEC50: 8nMAssay Description:Inhibition of wild type Influenza A virus (A/chicken/Hubei/327/2004(H5N1)) M2 channel expressed in yeast after 46 to 48 hrs by yeast growth restorati...More data for this Ligand-Target Pair
Affinity DataKd: 16nMAssay Description:Binding affinity to Influenza A Weybridge(H7N7) virus Matrix protein 2 by spectrophotometryMore data for this Ligand-Target Pair
TargetMatrix protein 2(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataKd: 130nMAssay Description:Binding affinity to C-terminal amidated influenza A virus A/Udorn/72 (H3N2) M2 transmembrane domain (22 to 46 residues) in DPC micelles at pH 8 asses...More data for this Ligand-Target Pair
Affinity DataKd: 130nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel by isothermal calorimetric titrationMore data for this Ligand-Target Pair
Affinity DataEC50: 140nMAssay Description:Inhibition of wild type Influenza A virus (A/chicken/Hubei/327/2004(H5N1)) M2 channel expressed in yeast after 46 to 48 hrs by yeast growth restorati...More data for this Ligand-Target Pair
Affinity DataEC50: 160nMAssay Description:Inhibition of wild type Influenza A virus (A/chicken/Hubei/327/2004(H5N1)) M2 channel expressed in yeast after 46 to 48 hrs by yeast growth restorati...More data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of Influenza A virus Udorn/72 M2 ion channel V27A mutant expressed in Xenopus oocyte plasma membranes after 2 mins by two-electrode voltag...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of influenza A virus A/Udorn/72 matrix protein 2 V27A mutant expressed in Xenopus laevis oocytes measured after 2 mins by two-electrode pa...More data for this Ligand-Target Pair
TargetMatrix protein 2(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataKd: 320nMAssay Description:Binding affinity to C-terminal amidated influenza A virus A/Udorn/72 (H3N2) M2 transmembrane domain (22 to 46 residues) in DPC micelles at pH 8 asses...More data for this Ligand-Target Pair
Affinity DataKd: 320nMAssay Description:Binding affinity to Influenza A Weybridge(H7N7) virus Matrix protein 2 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataEC50: 320nMAssay Description:Inhibition of wild type Influenza A virus (A/chicken/Hubei/327/2004(H5N1)) M2 channel expressed in yeast after 46 to 48 hrs by yeast growth restorati...More data for this Ligand-Target Pair
Affinity DataKd: 320nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel by isothermal calorimetric titrationMore data for this Ligand-Target Pair
TargetMatrix protein 2(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataKd: 340nMAssay Description:Binding affinity to C-terminal amidated influenza A virus A/Udorn/72 (H3N2) M2 transmembrane domain (22 to 46 residues) in DPC micelles at pH 8 asses...More data for this Ligand-Target Pair
Affinity DataKd: 340nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel by isothermal calorimetric titrationMore data for this Ligand-Target Pair
Affinity DataEC50: 370nMAssay Description:Inhibition of wild type Influenza A virus (A/chicken/Hubei/327/2004(H5N1)) M2 channel expressed in yeast after 46 to 48 hrs by yeast growth restorati...More data for this Ligand-Target Pair
Affinity DataKd: 390nMAssay Description:Binding affinity to Influenza A Weybridge(H7N7) virus Matrix protein 2 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataEC50: 390nMAssay Description:Inhibition of wild type Influenza A virus (A/chicken/Hubei/327/2004(H5N1)) M2 channel expressed in yeast after 46 to 48 hrs by yeast growth restorati...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of influenza A virus A/Udorn/72 matrix protein 2 V27A mutant expressed in Xenopus laevis oocytes measured after 2 mins by two-electrode pa...More data for this Ligand-Target Pair
Affinity DataEC50: 420nMAssay Description:Inhibition of wild type Influenza A virus (A/chicken/Hubei/327/2004(H5N1)) M2 channel expressed in yeast after 46 to 48 hrs by yeast growth restorati...More data for this Ligand-Target Pair
Affinity DataEC50: 440nMAssay Description:Inhibition of wild type Influenza A virus (A/chicken/Hubei/327/2004(H5N1)) M2 channel expressed in yeast after 46 to 48 hrs by yeast growth restorati...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of influenza A virus A/Udorn/72 matrix protein 2 V27A mutant expressed in Xenopus laevis oocytes measured after 2 mins by two-electrode pa...More data for this Ligand-Target Pair
TargetMatrix protein 2(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataKd: 510nMAssay Description:Binding affinity to C-terminal amidated influenza A virus A/Udorn/72 (H3N2) M2 transmembrane domain (22 to 46 residues) in DPC micelles at pH 8 asses...More data for this Ligand-Target Pair
Affinity DataKd: 510nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel by isothermal calorimetric titrationMore data for this Ligand-Target Pair
Affinity DataKd: 510nMAssay Description:Binding affinity to Influenza A Weybridge(H7N7) virus Matrix protein 2 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataEC50: 550nMAssay Description:Inhibition of wild type Influenza A virus (A/chicken/Hubei/327/2004(H5N1)) M2 channel expressed in yeast after 46 to 48 hrs by yeast growth restorati...More data for this Ligand-Target Pair
Affinity DataEC50: 560nMAssay Description:Inhibition of wild type Influenza A virus (A/chicken/Hubei/327/2004(H5N1)) M2 channel expressed in yeast after 46 to 48 hrs by yeast growth restorati...More data for this Ligand-Target Pair
Affinity DataEC50: 660nMAssay Description:Inhibition of wild type Influenza A virus (A/chicken/Hubei/327/2004(H5N1)) M2 channel expressed in yeast after 46 to 48 hrs by yeast growth restorati...More data for this Ligand-Target Pair
Affinity DataEC50: 670nMAssay Description:Inhibition of wild type Influenza A virus (A/chicken/Hubei/327/2004(H5N1)) M2 channel expressed in yeast after 46 to 48 hrs by yeast growth restorati...More data for this Ligand-Target Pair
Affinity DataEC50: 770nMAssay Description:Inhibition of wild type Influenza A virus (A/chicken/Hubei/327/2004(H5N1)) M2 channel expressed in yeast after 46 to 48 hrs by yeast growth restorati...More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of wild type Influenza A virus (A/udorn/1972(H3N2)) M2 channel expressed in Xenopus oocyte plasma membranes after 2 mins by two-electrode ...More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of Influenza A virus wild type M2 proton channel infected in Xenopus laevis oocytes after 2 mins by TEVC assayMore data for this Ligand-Target Pair
TargetMatrix protein 2(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of wild type influenza A virus A/Udorn/72 matrix protein 2 expressed in Xenopus laevis oocytes measured after 2 mins by two-electrode patc...More data for this Ligand-Target Pair
Affinity DataEC50: 950nMAssay Description:Inhibition of wild type Influenza A virus (A/chicken/Hubei/327/2004(H5N1)) M2 channel expressed in yeast after 46 to 48 hrs by yeast growth restorati...More data for this Ligand-Target Pair
TargetMatrix protein 2(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataEC50: 1.08E+3nMAssay Description:Inhibition of wild type influenza A virus H5N1 (A/chicken/Hubei/327/2004) matrix protein 2 transfected in yeast assessed as yeast growth restoration ...More data for this Ligand-Target Pair
Affinity DataKd: 1.16E+3nMAssay Description:Binding affinity to Influenza A Weybridge(H7N7) virus Matrix protein 2 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of wild type Influenza A virus (A/udorn/72(H3N2)) M2 channel expressed in Xenopus oocyte plasma membrane incubated for 2 mins measured ove...More data for this Ligand-Target Pair
TargetMatrix protein 2(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataEC50: 1.40E+3nMAssay Description:Inhibition of wild type influenza A virus H5N1 (A/chicken/Hubei/327/2004) matrix protein 2 transfected in yeast assessed as yeast growth restoration ...More data for this Ligand-Target Pair
Affinity DataKd: 1.49E+3nMAssay Description:Binding affinity to Influenza A Weybridge(H7N7) virus Matrix protein 2 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of wild type Influenza A virus (A/udorn/72(H3N2)) M2 channel expressed in Xenopus oocyte plasma membrane incubated for 2 mins measured ove...More data for this Ligand-Target Pair
Affinity DataKd: 1.50E+3nMAssay Description:Binding affinity to Influenza A Weybridge(H7N7) virus Matrix protein 2 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKd: 1.51E+3nMAssay Description:Binding affinity to Influenza A Weybridge(H7N7) virus Matrix protein 2 by spectrophotometryMore data for this Ligand-Target Pair
TargetMatrix protein 2(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataEC50: 1.58E+3nMAssay Description:Inhibition of wild type influenza A virus H5N1 (A/chicken/Hubei/327/2004) matrix protein 2 transfected in yeast assessed as yeast growth restoration ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of wild type Influenza A virus (A/udorn/72(H3N2)) M2 channel expressed in Xenopus oocyte plasma membrane incubated for 2 mins measured ove...More data for this Ligand-Target Pair
TargetMatrix protein 2(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataEC50: 1.71E+3nMAssay Description:Inhibition of wild type influenza A virus H5N1 (A/chicken/Hubei/327/2004) matrix protein 2 transfected in yeast assessed as yeast growth restoration ...More data for this Ligand-Target Pair
Affinity DataKd: 1.83E+3nMAssay Description:Binding affinity to Influenza A Weybridge(H7N7) virus Matrix protein 2 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes at pH 5.5 after 2 mins at -20 mV holding p...More data for this Ligand-Target Pair
Affinity DataIC50: 2.08E+3nMAssay Description:Inhibition of wild type Influenza A virus (A/udorn/72(H3N2)) M2 channel expressed in Xenopus oocyte plasma membrane incubated for 2 mins measured ove...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of wild type Influenza A virus (A/udorn/1972(H3N2)) M2 channel expressed in Xenopus oocyte plasma membranes after 2 mins by two-electrode ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of wild type Influenza A virus (A/udorn/1972(H3N2)) M2 channel expressed in Xenopus oocyte plasma membranes after 2 mins by two-electrode ...More data for this Ligand-Target Pair
Affinity DataKd: 2.17E+3nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel by isothermal calorimetric titrationMore data for this Ligand-Target Pair







3D Structure (crystal)

































