Compile Data Set for Download or QSAR
Report error Found 85 Enz. Inhib. hit(s) with Target = 'Mas-related G-protein coupled receptor member X2'
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM224022(Codeine-6G | Codeine-6-glucuronide)
Affinity DataEC50:  4.40E+4nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
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PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM224027(KNT-127)
Affinity DataEC50:  1.90E+4nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
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PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM224026(Dynorphin B (1-13) | YGGFLRRQFKVVT)
Affinity DataEC50:  3.30E+4nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
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PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM224025(Dynorphin A (1-17) | YGGFLRRXRPKLKWDNQ)
Affinity DataEC50:  2.10E+4nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
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PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM224024(Dynorphin A (1-13) | YGGFLRRXRPKLK | BDBM50241435)
Affinity DataEC50:  3.00E+4nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
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PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM50386689(HYDROCODONE | Dihydrocodinone)
Affinity DataEC50:  1.90E+4nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM224023(Dextrorphan)
Affinity DataEC50:  4.20E+3nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM213826(Dextromethorphan | US11535596, Compound Dextrometh...)
Affinity DataEC50:  3.20E+3nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
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PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM85324(CORTISTATIN-14 | CAS_186901-48-4 | cortistatin14)
Affinity DataEC50:  140nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
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PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM224028(Levorphanol)
Affinity DataEC50:  2.20E+4nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
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PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM224021(BAM8-22 | VGRPEWWMDYQKRYG)
Affinity DataEC50:  1.10E+4nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
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PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM50252954(N,N-diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperi...)
Affinity DataEC50:  5.10E+3nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM224020(6-Acetylmorphine)
Affinity DataEC50:  1.20E+4nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
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PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM224019(6-Acetylcodeine)
Affinity DataEC50:  1.90E+4nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
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PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM82507(CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...)
Affinity DataEC50:  4.40E+4nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
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PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM224018((+)-TAN-67)
Affinity DataEC50:  430nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM224017((+)-Morphine | US10752592, Compound morphine | US1...)
Affinity DataEC50:  3.40E+3nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM50413340(CHEMBL505715)
Affinity DataEC50:  501nMAssay Description:Agonist activity at human MrgX2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM50596259(CHEMBL5184932)
Affinity DataEC50:  290nMAssay Description:Agonistic activity at MRGPRX2 (unknown origin)More data for this Ligand-Target Pair
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PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM391726(US10300056, Example 11 | N-[(2R)-3-(7-methyl-1H- |...)
Affinity DataEC50:  900nMAssay Description:Agonist activity at MRGPX2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM50413344(CHEMBL503688)
Affinity DataEC50:  158nMAssay Description:Agonist activity at human MrgX2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM50413343(CHEMBL463274)
Affinity DataEC50:  316nMAssay Description:Agonist activity at human MrgX2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM50413341(CHEMBL502480)
Affinity DataEC50:  398nMAssay Description:Agonist activity at human MrgX2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM50413339(CHEMBL502132)
Affinity DataEC50:  631nMAssay Description:Agonist activity at human MrgX2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM50413336(CHEMBL503202)
Affinity DataEC50:  1.26E+3nMAssay Description:Agonist activity at human MrgX2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM50413334(CHEMBL505263)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at human MrgX2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM224014((-)-Metazocine)
Affinity DataEC50:  1.50E+4nMpH: 7.4 T: 2°CAssay Description:MRGPRX2 stable cells were maintained in DMEM containing 10% FBS, 100 μg/ml hygromycin B, and 15 μg/ml blasticidin. For the calcium mobiliza...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM224032(Thebaine)
Affinity DataEC50:  1.10E+4nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM50290872((-)-rel-3-((4aR,12aS)-2-methyl-1,2,3,4,4a,5,12,12a...)
Affinity DataEC50:  1.80E+3nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
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PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM50001450(Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met NH2 | ...)
Affinity DataEC50:  5.10E+3nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM224031(Sinomenine)
Affinity DataEC50:  5.40E+3nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM224030(Norcodeine)
Affinity DataEC50:  1.60E+4nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM50370478(Morphine 6-Glucuronide(Minor) | MORPHINE-6-GLUCURO...)
Affinity DataEC50:  1.90E+4nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM224029(Morphine-3G | Morphine-3-glucuronide)
Affinity DataEC50:  2.80E+4nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM224018((+)-TAN-67)
Affinity DataEC50:  290nMpH: 7.4 T: 2°CAssay Description:MRGPRX2 stable cells were maintained in DMEM containing 10% FBS, 100 μg/ml hygromycin B, and 15 μg/ml blasticidin. For the calcium mobiliza...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM50386689(HYDROCODONE | Dihydrocodinone)
Affinity DataEC50:  1.10E+4nMpH: 7.4 T: 2°CAssay Description:MRGPRX2 stable cells were maintained in DMEM containing 10% FBS, 100 μg/ml hygromycin B, and 15 μg/ml blasticidin. For the calcium mobiliza...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM224023(Dextrorphan)
Affinity DataEC50:  3.90E+3nMpH: 7.4 T: 2°CAssay Description:MRGPRX2 stable cells were maintained in DMEM containing 10% FBS, 100 μg/ml hygromycin B, and 15 μg/ml blasticidin. For the calcium mobiliza...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM213826(Dextromethorphan | US11535596, Compound Dextrometh...)
Affinity DataEC50:  5.90E+3nMpH: 7.4 T: 2°CAssay Description:MRGPRX2 stable cells were maintained in DMEM containing 10% FBS, 100 μg/ml hygromycin B, and 15 μg/ml blasticidin. For the calcium mobiliza...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM85324(CORTISTATIN-14 | CAS_186901-48-4 | cortistatin14)
Affinity DataEC50:  420nMpH: 7.4 T: 2°CAssay Description:MRGPRX2 stable cells were maintained in DMEM containing 10% FBS, 100 μg/ml hygromycin B, and 15 μg/ml blasticidin. For the calcium mobiliza...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM224021(BAM8-22 | VGRPEWWMDYQKRYG)
Affinity DataEC50:  8.90E+3nMpH: 7.4 T: 2°CAssay Description:MRGPRX2 stable cells were maintained in DMEM containing 10% FBS, 100 μg/ml hygromycin B, and 15 μg/ml blasticidin. For the calcium mobiliza...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM82083(CB0427223 | CAS_69671-17-6 | Alpha-Neoendorphin)
Affinity DataEC50:  4.30E+3nMpH: 7.4 T: 2°CAssay Description:MRGPRX2 stable cells were maintained in DMEM containing 10% FBS, 100 μg/ml hygromycin B, and 15 μg/ml blasticidin. For the calcium mobiliza...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM224020(6-Acetylmorphine)
Affinity DataEC50:  2.10E+4nMpH: 7.4 T: 2°CAssay Description:MRGPRX2 stable cells were maintained in DMEM containing 10% FBS, 100 μg/ml hygromycin B, and 15 μg/ml blasticidin. For the calcium mobiliza...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM224019(6-Acetylcodeine)
Affinity DataEC50:  2.50E+4nMpH: 7.4 T: 2°CAssay Description:MRGPRX2 stable cells were maintained in DMEM containing 10% FBS, 100 μg/ml hygromycin B, and 15 μg/ml blasticidin. For the calcium mobiliza...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM224015((+)-Codeine)
Affinity DataEC50:  5.50E+3nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM224017((+)-Morphine | US10752592, Compound morphine | US1...)
Affinity DataEC50:  5.00E+3nMpH: 7.4 T: 2°CAssay Description:MRGPRX2 stable cells were maintained in DMEM containing 10% FBS, 100 μg/ml hygromycin B, and 15 μg/ml blasticidin. For the calcium mobiliza...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM224016((+)-Metazocine)
Affinity DataEC50:  9.30E+3nMpH: 7.4 T: 2°CAssay Description:MRGPRX2 stable cells were maintained in DMEM containing 10% FBS, 100 μg/ml hygromycin B, and 15 μg/ml blasticidin. For the calcium mobiliza...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM224015((+)-Codeine)
Affinity DataEC50:  1.40E+4nMpH: 7.4 T: 2°CAssay Description:MRGPRX2 stable cells were maintained in DMEM containing 10% FBS, 100 μg/ml hygromycin B, and 15 μg/ml blasticidin. For the calcium mobiliza...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM50037483((6S,11R)-6,11-Dimethyl-1,2,3,4,5,6-hexahydro-2,6-m...)
Affinity DataEC50:  1.30E+4nMpH: 7.4 T: 2°CAssay Description:MRGPRX2 stable cells were maintained in DMEM containing 10% FBS, 100 μg/ml hygromycin B, and 15 μg/ml blasticidin. For the calcium mobiliza...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM82269(PROPOXYPHENE | CAS_469-62-5 | Propoxyphene-d | (+)...)
Affinity DataEC50:  3.20E+4nMpH: 7.4 T: 2°CAssay Description:MRGPRX2 stable cells were maintained in DMEM containing 10% FBS, 100 μg/ml hygromycin B, and 15 μg/ml blasticidin. For the calcium mobiliza...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMas-related G-protein coupled receptor member X2(Human)
University of North Carolina

LigandPNGBDBM50000092(Analog of 14-(Arylhydroxyamino)codeinone | 4-methy...)
Affinity DataEC50:  6.60E+3nMpH: 7.4 T: 2°CAssay Description:MRGPRX2 stable cells were maintained in DMEM containing 10% FBS, 100 μg/ml hygromycin B, and 15 μg/ml blasticidin. For the calcium mobiliza...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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