Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor [538-972]'
TargetMacrophage colony-stimulating factor 1 receptor [538-972](Human)
Deciphera Pharmaceuticals

US Patent
LigandPNGBDBM181020(US9133183, Example 29)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:Activity of unphosphorylated c-FMS kinase (uFMS, Seq. ID no. 1) was determined by following the production of ADP from the FMS kinase reaction with A...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMacrophage colony-stimulating factor 1 receptor [538-972](Human)
Deciphera Pharmaceuticals

US Patent
LigandPNGBDBM181019(US9133183, Example 15)
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:Activity of unphosphorylated c-FMS kinase (uFMS, Seq. ID no. 1) was determined by following the production of ADP from the FMS kinase reaction with A...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMacrophage colony-stimulating factor 1 receptor [538-972](Human)
Deciphera Pharmaceuticals

US Patent
LigandPNGBDBM181027(US9133183, Example 90)
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:Activity of unphosphorylated c-FMS kinase (uFMS, Seq. ID no. 1) was determined by following the production of ADP from the FMS kinase reaction with A...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMacrophage colony-stimulating factor 1 receptor [538-972](Human)
Deciphera Pharmaceuticals

US Patent
LigandPNGBDBM181018(US9133183, Example 1)
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:Activity of unphosphorylated c-FMS kinase (uFMS, Seq. ID no. 1) was determined by following the production of ADP from the FMS kinase reaction with A...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMacrophage colony-stimulating factor 1 receptor [538-972](Human)
Deciphera Pharmaceuticals

US Patent
LigandPNGBDBM181034(US9133183, Example 91)
Affinity DataIC50: 7nMpH: 7.5 T: 2°CAssay Description:Activity of unphosphorylated c-FMS kinase (uFMS, Seq. ID no. 1) was determined by following the production of ADP from the FMS kinase reaction with A...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMacrophage colony-stimulating factor 1 receptor [538-972](Human)
Deciphera Pharmaceuticals

US Patent
LigandPNGBDBM181037(US9133183, Example 42)
Affinity DataIC50: 8nMpH: 7.5 T: 2°CAssay Description:Activity of unphosphorylated c-FMS kinase (uFMS, Seq. ID no. 1) was determined by following the production of ADP from the FMS kinase reaction with A...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMacrophage colony-stimulating factor 1 receptor [538-972](Human)
Deciphera Pharmaceuticals

US Patent
LigandPNGBDBM181035(US9133183, Example 101)
Affinity DataIC50: 8nMpH: 7.5 T: 2°CAssay Description:Activity of unphosphorylated c-FMS kinase (uFMS, Seq. ID no. 1) was determined by following the production of ADP from the FMS kinase reaction with A...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMacrophage colony-stimulating factor 1 receptor [538-972](Human)
Deciphera Pharmaceuticals

US Patent
LigandPNGBDBM181023(US9133183, Compound A)
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:Activity of unphosphorylated c-FMS kinase (uFMS, Seq. ID no. 1) was determined by following the production of ADP from the FMS kinase reaction with A...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMacrophage colony-stimulating factor 1 receptor [538-972](Human)
Deciphera Pharmaceuticals

US Patent
LigandPNGBDBM181026(US9133183, Example 18)
Affinity DataIC50: 20nMpH: 7.5 T: 2°CAssay Description:Activity of unphosphorylated c-FMS kinase (uFMS, Seq. ID no. 1) was determined by following the production of ADP from the FMS kinase reaction with A...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMacrophage colony-stimulating factor 1 receptor [538-972]()
Johnson & Johnson Pharmaceutical

LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 57nMpH: 7.5 T: 2°CAssay Description:The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor [538-972]()
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17015(CHEMBL86755 | Indolinone based inhibitor, 1 | (3Z)...)
Affinity DataIC50: 1.20E+3nMpH: 7.5 T: 2°CAssay Description:The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor [538-972]()
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17749(JNJ31117164)
Affinity DataIC50: 1.20E+3nMpH: 7.5 T: 2°CAssay Description:The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor [538-972]()
Johnson & Johnson Pharmaceutical

LigandPNGBDBM4363(alpha-Cyano-(3,4-dihydroxy)thiocinnamide | CHEMBL7...)
Affinity DataIC50: 2.90E+3nMpH: 7.5 T: 2°CAssay Description:The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor [538-972]()
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17747(CHEMBL328710 | (3Z)-3-{[4-(dimethylamino)phenyl]me...)
Affinity DataIC50: 4.70E+3nMpH: 7.5 T: 2°CAssay Description:The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor [538-972]()
Johnson & Johnson Pharmaceutical

LigandPNGBDBM7393(Indirubin-3 -monoxime | 3-[(2Z,3E)-3-(hydroxyimino...)
Affinity DataIC50: 4.80E+3nMpH: 7.5 T: 2°CAssay Description:The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor [538-972]()
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17748(2-(3,4-Dihydroxyphenyl)-6,7-dimethylquinoxaline | ...)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed