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Report error Found 1089 Enz. Inhib. hit(s) with Target = 'M-phase inducer phosphatase 2'
TargetM-phase inducer phosphatase 2(Mouse)
Plex Pharmaceuticals

US Patent
LigandPNGBDBM690482(US12065407, ID CAP01324)
Affinity DataKi:  16nMAssay Description:Ligand binding was measured by fluorescence polarization of a fluorescein isothiocyanate (FITC) labeled probe (as described by Bollini, et al 2002) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612010(CHEMBL5271462)
Affinity DataIC50: 53nMAssay Description:Inhibition of recombinant CDC25B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612011(CHEMBL5288122)
Affinity DataIC50: 53nMAssay Description:Inhibition of recombinant CDC25B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetM-phase inducer phosphatase 2(Mouse)
Plex Pharmaceuticals

US Patent
LigandPNGBDBM690462(US12065407, ID CAP01723)
Affinity DataKi:  69nMAssay Description:Ligand binding was measured by fluorescence polarization of a fluorescein isothiocyanate (FITC) labeled probe (as described by Bollini, et al 2002) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50267086(Adociaquinone B | CHEMBL476648)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant CDC25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50267086(Adociaquinone B | CHEMBL476648)
Affinity DataIC50: 70nMAssay Description:Inhibition of Cdc25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM41999(MLS-0111617.0001 | 3-(3,4,5-trihydroxy-6-oxo-9-xan...)
Affinity DataKi:  80nMAssay Description:Competitive inhibition of recombinant phosphatase activity of Cdc25B catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50267086(Adociaquinone B | CHEMBL476648)
Affinity DataIC50: 80nMAssay Description:Inhibition of histidine-tagged full length human Cdc25B expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Mouse)
Plex Pharmaceuticals

US Patent
LigandPNGBDBM690478(US12065407, ID CAP01318)
Affinity DataKi:  90nMAssay Description:Ligand binding was measured by fluorescence polarization of a fluorescein isothiocyanate (FITC) labeled probe (as described by Bollini, et al 2002) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50106497(NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...)
Affinity DataKi:  95nMAssay Description:Inhibition of human Cdc25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM41999(MLS-0111617.0001 | 3-(3,4,5-trihydroxy-6-oxo-9-xan...)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant phosphatase activity of Cdc25B catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate by spectrof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50208827(NSC-95397 | cid_262093 | N1786 (NSC95397) | CHEMBL...)
Affinity DataIC50: 100nMAssay Description:Inhibition of GST tagged Cdc25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50267086(Adociaquinone B | CHEMBL476648)
Affinity DataIC50: 110nMAssay Description:Inhibition of histidine-tagged human recombinant Cdc25B catalytic domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50317356(3-(3-stearoyl-1H-pyrazole-5-carboxamido)thiophene-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of CDC25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50177318(2-(4-(7-(4-tetradecylbenzoyl)cyclopenta[d][1,2]oxa...)
Affinity DataIC50: 120nMAssay Description:Inhibitory activity against cdc25B phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50208827(NSC-95397 | cid_262093 | N1786 (NSC95397) | CHEMBL...)
Affinity DataIC50: 125nMAssay Description:Inhibition of human Cdc25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50317355(2-(3-stearoyl-1H-pyrazole-5-carboxamido)benzoic ac...)
Affinity DataIC50: 160nMAssay Description:Inhibition of CDC25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50317365(5-(4-chlorophenyl)-3-stearoylpyrrolo[3,4-c]pyrazol...)
Affinity DataIC50: 170nMAssay Description:Inhibition of CDC25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50627011(CHEMBL5423941)
Affinity DataIC50: 190nMAssay Description:Inhibition of full-length recombinant human CDC25B using OMFP as substrate incubated for 5 to 8 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50297586(N-(1-benzyl-3-cyano-1H-pyrrolo[3,2-b]quinoxalin-2-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of GST-fused Cdc25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM124256((3S,3aR,4S,7aS)-4-acetyl-7-dodecyl-3-methyl-1-oxo-...)
Affinity DataIC50: 200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2014
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Mouse)
Plex Pharmaceuticals

US Patent
LigandPNGBDBM63549(cid_2851304 | N,N-dimethyl-4-[(1-methyl-2-benzimid...)
Affinity DataKi:  200nMAssay Description:Ligand binding was measured by fluorescence polarization of a fluorescein isothiocyanate (FITC) labeled probe (as described by Bollini, et al 2002) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)
Affinity DataIC50: 210nMAssay Description:Inhibition of human recombinant GST-tagged CDC25B expressed in Escherichia coli BL21 (DE3) using pNPP as substrate measured for 2 mins by colorimetri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50106497(NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...)
Affinity DataIC50: 210nMAssay Description:Inhibitory activity against recombinant human cell division cycle 25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50297585(N-(1-benzyl-1H-pyrrolo[3,2-b]quinoxalin-2-yl)benze...)
Affinity DataIC50: 210nMAssay Description:Inhibition of GST-fused Cdc25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM124255((3S,3aR,4S,7R,7aS)-4-acetyl-7-dodecyl-3-methyl-1-o...)
Affinity DataIC50: 220nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2014
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM31040(1-Ethyl-6-methyl-3-phenyl-1H-pyrimido[5,4-e][1,2,4...)
Affinity DataIC50: 223nMAssay Description:The Cdc25B Phosphatase Secondary Selectivity Assay has been developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) part...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2011
Entry Details
PCBioAssay
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50317352(5-phenyl-3-stearoylpyrrolo[3,4-c]pyrazole-4,6(1H,5...)
Affinity DataIC50: 230nMAssay Description:Inhibition of CDC25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50317364(5-(3-chlorophenyl)-3-stearoylpyrrolo[3,4-c]pyrazol...)
Affinity DataIC50: 240nMAssay Description:Inhibition of CDC25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50341995(5-(2-(dimethylamino)ethylamino)-2,6-dimethylbenzo[...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human Cdc25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50504361(CHEMBL4452484)
Affinity DataIC50: 250nMAssay Description:Inhibition of recombinant Cdc25B (unknown origin) using OMFP as substrate measured every 30 sec for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50504361(CHEMBL4452484)
Affinity DataIC50: 250nMAssay Description:Inhibition of CDC25B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50317366(5-(2-bromophenyl)-3-stearoylpyrrolo[3,4-c]pyrazole...)
Affinity DataIC50: 250nMAssay Description:Inhibition of CDC25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50099736(4-ethoxynaphthalene-1,2-dione | 4-Ethoxy-[1,2]naph...)
Affinity DataIC50: 270nMAssay Description:Inhibition of histidine-tagged human recombinant Cdc25B catalytic domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50106505(6-Chloro-7-(indan-1-ylamino)-quinoline-5,8-dione |...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against recombinant human cell division cycle 25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Mouse)
Plex Pharmaceuticals

US Patent
LigandPNGBDBM690481(US12065407, ID CAP01328)
Affinity DataKi:  310nMAssay Description:Ligand binding was measured by fluorescence polarization of a fluorescein isothiocyanate (FITC) labeled probe (as described by Bollini, et al 2002) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50317382(5-(naphthalen-1-yl)-3-stearoylpyrrolo[3,4-c]pyrazo...)
Affinity DataIC50: 310nMAssay Description:Inhibition of CDC25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50317376(3-stearoyl-5-(2-(trifluoromethyl)phenyl)pyrrolo[3,...)
Affinity DataIC50: 320nMAssay Description:Inhibition of CDC25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50512278(CHEMBL4475724)
Affinity DataIC50: 320nMAssay Description:Inhibition of human recombinant GST-tagged CDC25B expressed in Escherichia coli BL21 (DE3) using pNPP as substrate measured for 2 mins by colorimetri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50317380(methyl 3-(4,6-dioxo-3-stearoylpyrrolo[3,4-c]pyrazo...)
Affinity DataIC50: 340nMAssay Description:Inhibition of CDC25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM32102(cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...)
Affinity DataIC50: 349nMAssay Description:The Cdc25B Phosphatase HTS dose response confirmation has been developed to confirm actives identified in the Cdc25B HTS AID 368, screened at the Uni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM26613((2E)-3-{3-[dihydroxy(oxo)--stibanyl]phenyl}prop-2-...)
Affinity DataKi:  369nMAssay Description:Inhibition of N-terminal His-tagged Cdc25b catalytic domain expressed in Escherichia coli BL21(DE3) using 3-O-Methylfluorescein phosphate as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50106491(5-Amino-6-(7-amino-6-methoxy-5,8-dioxo-5,8-dihydro...)
Affinity DataIC50: 370nMAssay Description:Inhibitory activity against recombinant human cell division cycle 25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50512277(CHEMBL4445615)
Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant GST-tagged CDC25B expressed in Escherichia coli BL21 (DE3) using pNPP as substrate measured for 2 mins by colorimetri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Mouse)
Plex Pharmaceuticals

US Patent
LigandPNGBDBM50104684((4-Hexadecanoyl-3-hydroxy-5-oxo-2,5-dihydro-furan-...)
Affinity DataIC50: 380nMAssay Description:Inhibitory activity against cell division cycle 25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM32102(cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...)
Affinity DataIC50: 396nMAssay Description:The MKP-1 Dual Specificity Protein Tyrosine Phosphatase Probe Assessment Cdc25B Dose Response Selectivity Assay has been developed to evaluate the PT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM31040(1-Ethyl-6-methyl-3-phenyl-1H-pyrimido[5,4-e][1,2,4...)
Affinity DataIC50: 400nMAssay Description:The Cdc25B Phosphatase HTS dose response confirmation has been developed to confirm actives identified in the Cdc25B HTS AID 368, screened at the Uni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50317359(5-(4-nitrophenyl)-3-stearoylpyrrolo[3,4-c]pyrazole...)
Affinity DataIC50: 400nMAssay Description:Inhibition of CDC25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50261252([((R)-4-Hexadecanoyl-3-hydroxy-5-oxo-2,5-dihydro-f...)
Affinity DataIC50: 400nMAssay Description:Inhibition of cdc25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Mouse)
Plex Pharmaceuticals

US Patent
LigandPNGBDBM50104691(Diazo-[2-(4-hexadecanoyl-3-hydroxy-5-oxo-2,5-dihyd...)
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against cell division cycle 25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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