Compile Data Set for Download or QSAR
Report error Found 122 Enz. Inhib. hit(s) with Target = 'Lysine--tRNA ligase'
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM482158(TAE684 | BDBM50242742)
Affinity DataEC50:  1.47E+3nMAssay Description:Inhibition of Syk by cellular assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50242740(Type II inhibitor, 14 | CHEMBL459850 | N-(3-(7-Ami...)
Affinity DataEC50:  71nMAssay Description:Inhibition of Syk by cellular assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataKd:  3.16E+3nMAssay Description:Binding affinity to SYK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50571529(CHEMBL4862068)
Affinity DataKd:  4.92E+4nMAssay Description:Binding affinity to human N-terminal His6-tagged 15N-labelled KRS (1 to 207 residues) expressed in Escherichia coli BL21(DE3) measured by flourescenc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50571530(CHEMBL4852870)
Affinity DataKd:  5.75E+3nMAssay Description:Binding affinity to human N-terminal His6-tagged 15N-labelled KRS (1 to 207 residues) expressed in Escherichia coli BL21(DE3) measured by flourescenc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50390557(CHEMBL2069346)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human recombinant full-length Syk using poly-GT as substrate after 40 mins by radioactive filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 0.860nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50390556(CHEMBL2069345)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant full-length Syk using poly-GT as substrate after 40 mins by radioactive filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50249539(5-((1S,2R)-2-aminocyclohexylamino)-7-(3,5-dimethox...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50390560(CHEMBL2069349)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant full-length Syk using poly-GT as substrate after 40 mins by radioactive filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50390561(CHEMBL2069350)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant full-length Syk using poly-GT as substrate after 40 mins by radioactive filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50390563(CHEMBL2069352)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant full-length Syk using poly-GT as substrate after 40 mins by radioactive filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50390568(CHEMBL2069358)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant full-length Syk using poly-GT as substrate after 40 mins by radioactive filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50390564(CHEMBL2069353)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant full-length Syk using poly-GT as substrate after 40 mins by radioactive filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50390566(CHEMBL2069355)
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant full-length Syk using poly-GT as substrate after 40 mins by radioactive filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50390567(CHEMBL2069357)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant full-length Syk using poly-GT as substrate after 40 mins by radioactive filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50465346(CHEMBL4286991)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50390562(CHEMBL2069351)
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant full-length Syk using poly-GT as substrate after 40 mins by radioactive filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50390569(CHEMBL2069359)
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant full-length Syk using poly-GT as substrate after 40 mins by radioactive filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50249254(5-((1S,2R)-2-aminocyclohexylamino)-7-(3,5-dimethox...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50249253(5-(2-aminoethylamino)-7-(3,5-dimethoxyphenylamino)...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50059889(3-methoxy-2-methyl-4-methylamino-(2S,3S,4S,6R)-29-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50390573(CHEMBL2069356)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant full-length Syk using poly-GT as substrate after 40 mins by radioactive filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50390571(CHEMBL2069360)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant full-length Syk using poly-GT as substrate after 40 mins by radioactive filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50465342(CHEMBL4293812)
Affinity DataIC50: 11nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50390552(CHEMBL2069341)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant full-length Syk using poly-GT as substrate after 40 mins by radioactive filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50465348(CHEMBL4292650)
Affinity DataIC50: 22nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50390555(CHEMBL2069344)
Affinity DataIC50: 27nMAssay Description:Inhibition of human recombinant full-length Syk using poly-GT as substrate after 40 mins by radioactive filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50390565(CHEMBL2069354)
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant full-length Syk using poly-GT as substrate after 40 mins by radioactive filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50143600(CHEBI:29571 | Dehydroabietic Acid)
Affinity DataIC50: 28nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50126419(N*1*-[7-(4-Dimethylamino-phenyl)-[1,6]naphthyridin...)
Affinity DataIC50: 34nMAssay Description:Inhibition of SYKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50465345(18-Oxoferruginol | acs.jmedchem.1c00409_ST.768)
Affinity DataIC50: 34nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50249319(CHEMBL471901 | 2-(2-aminoethylamino)-4-(3-(trifluo...)
Affinity DataIC50: 41nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50390559(CHEMBL2069348)
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant full-length Syk using poly-GT as substrate after 40 mins by radioactive filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50465347(POMIFERIN A | CHEBI:52486)
Affinity DataIC50: 46nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50465338(CHEMBL598566 | 15-Hydroxydehydroabietic Acid)
Affinity DataIC50: 49nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50263121(cis-5-(2-Aminocyclohexylamino)-7-(3,5-dimethoxyphe...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50390558(CHEMBL2069347)
Affinity DataIC50: 62nMAssay Description:Inhibition of human recombinant full-length Syk using poly-GT as substrate after 40 mins by radioactive filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50426528(CHEMBL2323633)
Affinity DataIC50: 65nMAssay Description:Inhibition of human Gst-tagged Syk expressed in sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50426527(CHEMBL2323632)
Affinity DataIC50: 71nMAssay Description:Inhibition of human Gst-tagged Syk expressed in sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50426530(CHEMBL2323635)
Affinity DataIC50: 71nMAssay Description:Inhibition of human Gst-tagged Syk expressed in sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50426525(CHEMBL2323631)
Affinity DataIC50: 79nMAssay Description:Inhibition of human Gst-tagged Syk expressed in sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50263119(cis-5-(2-Aminocyclohexylamino)-7-(3,5-dimethoxyphe...)
Affinity DataIC50: 83nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50465343(CHEMBL4279751)
Affinity DataIC50: 85nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50390570(CHEMBL2069337)
Affinity DataIC50: 91nMAssay Description:Inhibition of human recombinant full-length Syk using poly-GT as substrate after 40 mins by radioactive filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50465339(CHEMBL4285076)
Affinity DataIC50: 100nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50465340(CHEMBL4278579)
Affinity DataIC50: 100nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50465341(CHEMBL4289234)
Affinity DataIC50: 100nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50465344(CHEMBL4294902)
Affinity DataIC50: 100nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine--tRNA ligase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50390554(CHEMBL2069343)
Affinity DataIC50: 114nMAssay Description:Inhibition of human recombinant full-length Syk using poly-GT as substrate after 40 mins by radioactive filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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