Compile Data Set for Download or QSAR
Report error Found 88 Enz. Inhib. hit(s) with Target = 'Low affinity immunoglobulin epsilon Fc receptor'
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069616((2R,3S)-N*1*-Hydroxy-2-{2-[(E)-hydroxyimino]-2-phe...)
Affinity DataIC50: 12nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069604([(2S,3R)-3-((S)-1-Carbamoyl-2-phenyl-ethylcarbamoy...)
Affinity DataIC50: 13nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069601((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)
Affinity DataIC50: 16nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082226((2R,3S)-N*4*-((S)-1-Carbamoyl-2,2-dimethyl-propyl)...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082225((2R,3S)-N*4*-((S)-1-Carbamoyl-2,2-dimethyl-propyl)...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082218((2R,3S)-2-Benzo[b]thiophen-2-ylmethyl-N*1*-((S)-1-...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069620((2R,3S)-N*1*-((S)-1-Carbamoyl-2-phenyl-ethyl)-N*4*...)
Affinity DataIC50: 20nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069597((2R,3S)-N*1*-((S)-1-Carbamoyl-2-phenyl-ethyl)-N*4*...)
Affinity DataIC50: 30nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069606((2R,3S)-2-Benzylsulfanylmethyl-N*1*-hydroxy-3-isob...)
Affinity DataIC50: 30nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 30-1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069610((2R,3S)-N*1*-Hydroxy-2-(4-hydroxy-phenylsulfanylme...)
Affinity DataIC50: 40nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 40-8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069608((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)
Affinity DataIC50: 40nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 40-8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069619(4-[(2S,3R)-2-Hydroxycarbamoyl-5-methyl-3-((S)-1-me...)
Affinity DataIC50: 50nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 50-1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069598((2R,3S)-N*4*-((S)-1-Carbamoyl-2-phenyl-ethyl)-2-{2...)
Affinity DataIC50: 60nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403719(CHEMBL2111687)
Affinity DataIC50: 70nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403718(CHEMBL2112477)
Affinity DataIC50: 70nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069621((2R,3S)-N*4*-Hydroxy-2-isobutyl-3-{2-[(E)-methoxyi...)
Affinity DataIC50: 80nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082221((2R,3S)-N*1*-((S)-1-Carbamoyl-2,2-dimethyl-propyl)...)
Affinity DataIC50: 80nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069600((2R,3S)-N*4*-((S)-1-Carbamoyl-2-phenyl-ethyl)-N*1*...)
Affinity DataIC50: 100nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069612(2-[(2S,3R)-2-Hydroxycarbamoyl-5-methyl-3-((S)-1-me...)
Affinity DataIC50: 100nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082216((2R,3S)-N*1*-((S)-1-Carbamoyl-2-phenyl-ethyl)-2-(7...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082214((2R,3S)-2-Benzofuran-2-ylmethyl-3,N*4*-dihydroxy-N...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069607((2R,3S)-2-Carbamoylmethylsulfanylmethyl-N*4*-((S)-...)
Affinity DataIC50: 100nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063918((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)
Affinity DataIC50: 100nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069605((2R,3S)-2-Benzyl-N*1*-((S)-1-carbamoyl-2-phenyl-et...)
Affinity DataIC50: 100nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063918((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)
Affinity DataIC50: 100nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 5-10More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132451(3-[1-(5-Methoxy-1-methyl-1H-indol-3-yl)-meth-(Z)-y...)
Affinity DataEC50:  100nMAssay Description:Effect on IgE/Fcepsilon RI triggered rat basophil cell (RBL-2H3) degranulation assessed by measuring the amount of 5-HT releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069603((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)
Affinity DataIC50: 100nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132433(3-[1-(5-Methoxy-1-methyl-1H-indol-3-yl)-meth-(Z)-y...)
Affinity DataEC50:  110nMAssay Description:Effect on IgE/Fcepsilon RI triggered rat basophil cell (RBL-2H3) degranulation assessed by measuring the amount of 5-HT releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069618((2R,3S)-2-Benzyl-N*1*-((S)-1-carbamoyl-2-phenyl-et...)
Affinity DataIC50: 130nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069609((2R,3S)-2-{2-Biphenyl-4-yl-2-[(E)-hydroxyimino]-et...)
Affinity DataIC50: 130nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069613((2R,3S)-N*1*-((S)-1-Carbamoyl-2-phenyl-ethyl)-N*4*...)
Affinity DataIC50: 130nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069595((2R,3S)-2-Benzyl-N*1*-((S)-1-carbamoyl-2-phenyl-et...)
Affinity DataIC50: 160nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069583((R)-N*1*-((S)-1-Benzylcarbamoyl-2-phenyl-ethyl)-2-...)
Affinity DataIC50: 200nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 5-10More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069611((2R,3S)-2-Benzyl-N*1*-((S)-1-carbamoyl-2-phenyl-et...)
Affinity DataIC50: 210nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082220((2R,3S)-N*1*-((S)-1-Carbamoyl-2-phenyl-ethyl)-2-(6...)
Affinity DataIC50: 220nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082229((2R,3S)-N*4*-((S)-2,2-Dimethyl-1-methylcarbamoyl-p...)
Affinity DataIC50: 230nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132436(3-((1-methyl-1H-indol-3-yl)methylene)-2-oxoindolin...)
Affinity DataEC50:  313nMAssay Description:Effect on IgE/Fcepsilon RI triggered rat basophil cell (RBL-2H3) degranulation assessed by measuring the amount of 5-HT releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082227((2R,3S)-2-Benzothiazol-2-ylmethyl-N*1*-((S)-1-carb...)
Affinity DataIC50: 320nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069614((2R,3S)-2-(2-Biphenyl-4-yl-2-oxo-ethylsulfanylmeth...)
Affinity DataIC50: 380nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082217((2R,3S)-2,N*1*-Dihydroxy-N*4*-((S)-1-methylcarbamo...)
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082215((2R,3S)-N*4*-((S)-1-Carbamoyl-2-phenyl-ethyl)-2,N*...)
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082224((2R,3S)-N*4*-((S)-1-Carbamoyl-2-phenyl-ethyl)-2,N*...)
Affinity DataIC50: 760nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082228((2R,3S)-N*4*-((S)-1-Carbamoyl-2,2-dimethyl-propyl)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031795((N-(2-HYDROXAMATEMETHYLENE-4-METHYL-PENTOYL)PHENYL...)
Affinity DataIC50: 1.00E+3nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 1000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069587((R)-N*1*-((S)-1-Benzylcarbamoyl-2-phenyl-ethyl)-N*...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069587((R)-N*1*-((S)-1-Benzylcarbamoyl-2-phenyl-ethyl)-N*...)
Affinity DataIC50: 1.00E+3nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 5-10More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069602(Thioacetic acid S-[(2S,3R)-3-((S)-1-carbamoyl-2-ph...)
Affinity DataIC50: 1.00E+3nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 1000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082231((2R,3S)-2-Benzo[b]thiophen-3-ylmethyl-3,N*4*-dihyd...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082230((2R,3S)-N*1*-((S)-1-Carbamoyl-2,2-dimethyl-propyl)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against IgE receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132450(3-[1-(5-Methoxy-1-methyl-1H-indol-3-yl)-meth-(Z)-y...)
Affinity DataEC50:  1.40E+3nMAssay Description:Effect on IgE/Fcepsilon RI triggered rat basophil cell (RBL-2H3) degranulation assessed by measuring the amount of 5-HT releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
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