Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with Target = 'Isoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)'
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataEC50:  4.60nMAssay Description:Agonist activity at ZFP-fused ERRbeta LBD expressed in HEK293 cells by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50336730(4-[4-(2,4-Dioxothiazolidin-5-ylidenemethyl)-2-meth...)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at ZFP-fused ERRbeta LBD expressed in HEK293 cells by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataIC50: 8.70nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50427842(CHEMBL2326072)
Affinity DataIC50: 19nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50427834(CHEMBL2326068)
Affinity DataIC50: 41nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212173(7-bromo-6H-chromeno[4,3-b]quinoline-3,9-diol | CHE...)
Affinity DataIC50: 56nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212166(7-chloro-6H-chromeno[4,3-b]quinoline-3,9-diol | CH...)
Affinity DataIC50: 88nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212172(3,9-dihydroxy-6H-chromeno[4,3-b]quinoline-7-carbon...)
Affinity DataIC50: 98nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50427836(CHEMBL2326070)
Affinity DataIC50: 112nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50427841(CHEMBL2326073)
Affinity DataIC50: 121nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50427835(CHEMBL2326069)
Affinity DataIC50: 151nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50427838(CHEMBL2326076)
Affinity DataIC50: 185nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50171724(4-Bromo-2-(4-hydroxy-phenyl)-quinolin-6-ol | 4-bro...)
Affinity DataIC50: 212nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50171726(4-chloro-2-(4-hydroxyphenyl)quinolin-6-ol | 4-Chlo...)
Affinity DataIC50: 213nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50427840(CHEMBL2326074)
Affinity DataIC50: 331nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM19459(Prunetol | Genisteol | CHEMBL44 | US8552057, 2 | c...)
Affinity DataIC50: 395nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50427839(CHEMBL2326075)
Affinity DataIC50: 436nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50171712(6-Hydroxy-2-(4-hydroxy-phenyl)-quinoline-4-carboni...)
Affinity DataIC50: 455nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50171727(2-(4-Hydroxy-phenyl)-4-vinyl-quinolin-6-ol | 2-(4-...)
Affinity DataIC50: 504nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212165(7-(3-chlorophenyl)-6H-chromeno[4,3-b]quinoline-3,9...)
Affinity DataIC50: 504nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212161(7-vinyl-6H-chromeno[4,3-b]quinoline-3,9-diol | CHE...)
Affinity DataIC50: 526nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212163(7-(4-methoxyphenyl)-6H-chromeno[4,3-b]quinoline-3,...)
Affinity DataIC50: 549nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50427837(CHEMBL2326071)
Affinity DataIC50: 566nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212170(7-ethynyl-6H-chromeno[4,3-b]quinoline-3,9-diol | C...)
Affinity DataIC50: 624nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50171723(4-Ethyl-2-(4-hydroxy-phenyl)-quinolin-6-ol | 4-eth...)
Affinity DataIC50: 634nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212162(7-ethyl-6H-chromeno[4,3-b]quinoline-3,9-diol | CHE...)
Affinity DataIC50: 641nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212167(7-(3-methoxyphenyl)-6H-chromeno[4,3-b]quinoline-3,...)
Affinity DataIC50: 820nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212168(4-(3,9-dihydroxy-6H-chromeno[4,3-b]quinolin-7-yl)b...)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212169(3-(3,9-dihydroxy-6H-chromeno[4,3-b]quinolin-7-yl)b...)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50171729(4-Ethynyl-2-(4-hydroxy-phenyl)-quinolin-6-ol | 4-e...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212164(7-(4-chlorophenyl)-6H-chromeno[4,3-b]quinoline-3,9...)
Affinity DataIC50: 2.35E+3nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212171(7-(4-(trifluoromethyl)phenyl)-6H-chromeno[4,3-b]qu...)
Affinity DataIC50: 5.24E+3nMAssay Description:Inhibition of human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed