Compile Data Set for Download or QSAR
Report error Found 740 Enz. Inhib. hit(s) with Target = 'Interleukin-2'
TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM50021400(CHEBI:74020 | DISOGLUSIDE)
Affinity DataKd:  0.0290nMAssay Description:Binding affinity to IL-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetInterleukin-21(Human)
Ariagen

US Patent
LigandPNGBDBM649497(US11891386, Compound ARI-083)
Affinity DataIC50: 0.300nMAssay Description:IL-21 levels in cell supernatants and cell-free control samples were measured using the ALPHALISA assay kit from Perkin Elmer, following the manufact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
Go to US Patent

TargetInterleukin-21(Human)
Ariagen

US Patent
LigandPNGBDBM649500(US11891386, Compound ARI-120)
Affinity DataIC50: 0.300nMAssay Description:IL-21 levels in cell supernatants and cell-free control samples were measured using the ALPHALISA assay kit from Perkin Elmer, following the manufact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM50579802(CHEMBL5081901)
Affinity DataEC50:  0.609nMAssay Description:Induction of stability of human recombinant interleukin 2 assessed as increase in mouse CTLL-2 cell proliferation measured after 48 hrs by WST-1 assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetInterleukin-21(Human)
Ariagen

US Patent
LigandPNGBDBM649499(US11891386, Compound ARI-118)
Affinity DataIC50: 0.800nMAssay Description:IL-21 levels in cell supernatants and cell-free control samples were measured using the ALPHALISA assay kit from Perkin Elmer, following the manufact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
Go to US Patent

TargetInterleukin-23 receptor(Human)
Centro De Investigaci£N Lilly

Curated by ChEMBL
LigandPNGBDBM50459752(CHEMBL4206167)
Affinity DataKd:  1.81nMAssay Description:Binding affinity to recombinant human flag/His-tagged IL-23R (1 to 353 residues) expressed in HEK293F cells measured over 90 secs by surface plasmon ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM50021396(CHEMBL3289607)
Affinity DataKd:  2.59nMAssay Description:Binding affinity to IL-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetInterleukin-23 receptor(Human)
Centro De Investigaci£N Lilly

Curated by ChEMBL
LigandPNGBDBM50459752(CHEMBL4206167)
Affinity DataIC50: 2.70nMAssay Description:Binding affinity to recombinant human flag/His-tagged IL-23R (1 to 353 residues) expressed in HEK293F cells assessed as disruption of biotinylated IL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM128384(US8802721, 1)
Affinity DataIC50: 3nMAssay Description:Jurkat cells were placed in a 96 well plate (0.5 million cells per well in 1% FBS medium) then a test compound of this invention was added at differe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
Go to US Patent

TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50229786(5-[2,3-Dichloro-4-(5-{1-[2-((R)-2-guanidino-4-meth...)
Affinity DataEC50:  3nMAssay Description:Effective concentration required against phosphorylation of Mammary gland factor/STAT5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-21(Human)
Ariagen

US Patent
LigandPNGBDBM649495(US11891386, Compound ARI-056)
Affinity DataIC50: 4.90nMAssay Description:IL-21 levels in cell supernatants and cell-free control samples were measured using the ALPHALISA assay kit from Perkin Elmer, following the manufact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
Go to US Patent

TargetInterleukin-2(Mouse)
Sandoz Pharma

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataIC50: 5nMAssay Description:The compound was evaluated in vitro for the immunosuppressive activity in interleukin-2 by interleukin-2 reporter gene assay (IL2-RGA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterleukin-23 receptor(Human)
Centro De Investigaci£N Lilly

Curated by ChEMBL
LigandPNGBDBM50459752(CHEMBL4206167)
Affinity DataIC50: 5.10nMAssay Description:Binding affinity to recombinant human flag/His-tagged IL-23R (1 to 353 residues) expressed in HEK293F cells assessed as disruption of biotinylated IL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetInterleukin-21(Human)
Ariagen

US Patent
LigandPNGBDBM649503(US11891386, Compound ARI-148)
Affinity DataIC50: 5.90nMAssay Description:IL-21 levels in cell supernatants and cell-free control samples were measured using the ALPHALISA assay kit from Perkin Elmer, following the manufact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
Go to US Patent

TargetInterleukin-21(Human)
Ariagen

US Patent
LigandPNGBDBM649487(US11891386, Compound ARI-067)
Affinity DataIC50: 6.30nMAssay Description:IL-21 levels in cell supernatants and cell-free control samples were measured using the ALPHALISA assay kit from Perkin Elmer, following the manufact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM128386(US8802721, 3)
Affinity DataIC50: 6.40nMAssay Description:Jurkat cells were placed in a 96 well plate (0.5 million cells per well in 1% FBS medium) then a test compound of this invention was added at differe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM412467(US10399967, Compound 98 | N-(5-(5-ethyl-2-(5-methy...)
Affinity DataIC50: 8nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM412475(US10399967, Compound 108 | 5-ethyl-N-(5-(5-ethyl-2...)
Affinity DataIC50: 8nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM50575333(CHEMBL4857063)
Affinity DataIC50: 8nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetInterleukin-21(Human)
Ariagen

US Patent
LigandPNGBDBM649498(US11891386, Compound ARI-090)
Affinity DataIC50: 8.40nMAssay Description:IL-21 levels in cell supernatants and cell-free control samples were measured using the ALPHALISA assay kit from Perkin Elmer, following the manufact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
Go to US Patent

TargetInterleukin-21(Human)
Ariagen

US Patent
LigandPNGBDBM649489(US11891386, Compound ARI-140)
Affinity DataIC50: 8.60nMAssay Description:IL-21 levels in cell supernatants and cell-free control samples were measured using the ALPHALISA assay kit from Perkin Elmer, following the manufact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM412445(US10399967, Compound 75 | N-(5-(2-chloro-5- cyclop...)
Affinity DataIC50: 9nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM412392(US10399967, Compound 22 | 5-fluoro-4-methyl-N-(5-(...)
Affinity DataIC50: 9nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM412443(US10399967, Compound 73 | 5-bromo-N-(5-(5-ethyl-2-...)
Affinity DataIC50: 9nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM50598492(CHEMBL5205694)
Affinity DataEC50:  9.40nMAssay Description:Inhibition of IL-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM412476(US10399967, Compound 109 | N-(5-(5-ethyl-2-(3-meth...)
Affinity DataIC50: 10nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM412479(US10399967, Compound 112 | N-(5-(5-ethyl-2-(isoxaz...)
Affinity DataIC50: 10nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM412441(US10399967, Compound 71 | N-(5-(2-chloro-5- cyclop...)
Affinity DataIC50: 10nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM412489(US10399967, Compound 122 | N-(5-(2-chloro-5-(1-met...)
Affinity DataIC50: 10nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM412442(US10399967, Compound 72 | 5-chloro-N-(5-(5-ethyl-2...)
Affinity DataIC50: 10nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM50587599(CHEMBL5087453 | US11661419, Example 53 | US2023028...)
Affinity DataIC50: 10nMAssay Description:Inhibition of IL-2 in CD3/CD28 activated human CD4+ve Th cells preincubated for 15 mins followed by addition of immuno-cult and measured after 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInterleukin-21(Human)
Ariagen

US Patent
LigandPNGBDBM649505(US11891386, Compound ARI-049)
Affinity DataIC50: 10.1nMAssay Description:IL-21 levels in cell supernatants and cell-free control samples were measured using the ALPHALISA assay kit from Perkin Elmer, following the manufact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM412481(US10399967, Compound 114 | 5-chloro-N-(5-(2-chloro...)
Affinity DataIC50: 11nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM412451(US10399967, Compound 81 | 5-bromo-N-(5-(2-chloro-5...)
Affinity DataIC50: 11nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM412447(US10399967, Compound 77 | N-(5-(5-ethyl-2-(5-methy...)
Affinity DataIC50: 11nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM412440(US10399967, Compound 70 | N-(5-(5-ethyl-2-(5-methy...)
Affinity DataIC50: 11nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM412488(US10399967, Compound 121 | 5-bromo-N-(5-(2-chloro-...)
Affinity DataIC50: 11nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM50575331(CHEMBL4868242)
Affinity DataIC50: 11nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM412468(US10399967, Compound 99 | 5-fluoro-4-methyl-N-(5-(...)
Affinity DataIC50: 11nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM412387(US10399967, Compound 17 | N-(2'-chloro-5'-(trifluo...)
Affinity DataIC50: 12nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM50636011(CHEMBL5560228)
Affinity DataEC50:  12nMAssay Description:Activation of IL-2 in human Jurkat cells incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM412432(N-(5-(2-chloro-5- cyclopropoxyphenyl)pyrazin-2-yl)...)
Affinity DataIC50: 12nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM412377(US10399967, Compound 7 | N-(5-(2-ethyl-5-(1-methyl...)
Affinity DataIC50: 12nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM412384(US10399967, Compound 14 | N-(5-(2-chloro-5-(5-meth...)
Affinity DataIC50: 13nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM50587592(CHEMBL5090091 | US11661419, Example 7 | US20230280...)
Affinity DataIC50: 13nMAssay Description:Inhibition of IL-2 in CD3/CD28 activated human CD4+ve Th cells preincubated for 15 mins followed by addition of immuno-cult and measured after 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM412446(US10399967, Compound 76 | 5-cyano-N-(5-(5-ethyl-2-...)
Affinity DataIC50: 13nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM412511(US10399967, Compound 144 | N-(5-(2-chloro-5- isopr...)
Affinity DataIC50: 13nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM412459(US10399967, Compound 90 | N-(5-(2-chloro-5- isopro...)
Affinity DataIC50: 13nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetInterleukin-2(Mouse)
Sandoz Pharma

Curated by ChEMBL
LigandPNGBDBM50422041(GECLOSPORIN)
Affinity DataIC50: 13nMAssay Description:The compound was evaluated in vitro for the immunosuppressive activity in interleukin-2 by interleukin-2 reporter gene assay (IL2-RGA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterleukin-21(Human)
Ariagen

US Patent
LigandPNGBDBM649502(US11891386, Compound ARI-146)
Affinity DataIC50: 13.4nMAssay Description:IL-21 levels in cell supernatants and cell-free control samples were measured using the ALPHALISA assay kit from Perkin Elmer, following the manufact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
Go to US Patent

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