Compile Data Set for Download or QSAR
Report error Found 166 Enz. Inhib. hit(s) with Target = 'Integrin-linked protein kinase'
TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50078259(CHEMBL3414669)
Affinity DataKd:  8.70E+3nMAssay Description:Binding affinity to GST-tagged PH domain of ILK (unknown origin) by surface Plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50078209(CHEMBL3414686)
Affinity DataKd:  6.20E+3nMAssay Description:Binding affinity to GST-tagged PH domain of ILK (unknown origin) by surface Plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50078207(CHEMBL3414688)
Affinity DataKd:  1.31E+4nMAssay Description:Binding affinity to GST-tagged PH domain of ILK (unknown origin) by surface Plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataKd:  430nMAssay Description:Thus, while these compounds were extensively used in studying ILK-mediated cellular and disease processes, their reported inhibitory effects are prob...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM582528(US11524945, Compound Gefitinib)
Affinity DataKd:  4.51E+3nMAssay Description:Thus, while these compounds were extensively used in studying ILK-mediated cellular and disease processes, their reported inhibitory effects are prob...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM582529(US11524945, Compound Erlotinib-4-methylphenyl anal...)
Affinity DataKd:  1.55E+3nMAssay Description:Thus, while these compounds were extensively used in studying ILK-mediated cellular and disease processes, their reported inhibitory effects are prob...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM582530(US11524945, Compound 1 (Csbl-1))
Affinity DataKd:  2.77E+3nMAssay Description:Thus, while these compounds were extensively used in studying ILK-mediated cellular and disease processes, their reported inhibitory effects are prob...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM582531(US11524945, Compound 3 (cmpd#3))
Affinity DataKd:  4.96E+4nMAssay Description:Thus, while these compounds were extensively used in studying ILK-mediated cellular and disease processes, their reported inhibitory effects are prob...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM582532(US11524945, Compound 4 (cmpd#4))
Affinity DataKd:  1.55E+3nMAssay Description:Thus, while these compounds were extensively used in studying ILK-mediated cellular and disease processes, their reported inhibitory effects are prob...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM582533(US11524945, Compound 1 New (cmpd#1new))
Affinity DataKd:  6.85E+3nMAssay Description:Thus, while these compounds were extensively used in studying ILK-mediated cellular and disease processes, their reported inhibitory effects are prob...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM582534(US11524945, Compound 2 New (cmpd#2new))
Affinity DataKd:  8.00E+3nMAssay Description:Thus, while these compounds were extensively used in studying ILK-mediated cellular and disease processes, their reported inhibitory effects are prob...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM582535(US11524945, Compound 7 (cmpd-#7))
Affinity DataKd:  2.45E+3nMAssay Description:Thus, while these compounds were extensively used in studying ILK-mediated cellular and disease processes, their reported inhibitory effects are prob...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM582536(US11524945, Compound 8 (Csbl-2))
Affinity DataKd:  922nMAssay Description:Thus, while these compounds were extensively used in studying ILK-mediated cellular and disease processes, their reported inhibitory effects are prob...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM123945(US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-5-...)
Affinity DataIC50: 7nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM123951(US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-be...)
Affinity DataIC50: 10nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM124052(US8754233, 5-(3-Amino-propyl)-4-benzothiazol-2-yl-...)
Affinity DataIC50: 10nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM123930(US8754233, 2-(3-Amino-1H-pyrazol-4-yl)-5-fluoro-be...)
Affinity DataIC50: 20nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM124022(US8754233, 4-Benzothiazol-2-yl-5-(3-methylamino-pr...)
Affinity DataIC50: 20nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM124067(US8754233, N3-(2-Amino-ethyl)-4-benzothiazol-2-yl-...)
Affinity DataIC50: 20nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM123933(US8754233, 2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-5-...)
Affinity DataIC50: 40nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM123943(US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-4-...)
Affinity DataIC50: 40nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM123965(US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-be...)
Affinity DataIC50: 40nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM123992(US8754233, 4-(5-Fluoro-6-methoxy-benzothiazol-2-yl...)
Affinity DataIC50: 40nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM124001(US8754233, 4-(5-Fluoro-benzothiazol-2-yl)-5-methyl...)
Affinity DataIC50: 40nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM123946(US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-5-...)
Affinity DataIC50: 50nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM123969(US8754233, 2-(5-Amino-3-pyridin-4-yl-1H-pyrazol-4-...)
Affinity DataIC50: 50nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM123999(US8754233, 4-(5-Fluoro-6-methyl-benzothiazol-2-yl)...)
Affinity DataIC50: 50nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM123932(US8754233, 2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-5-...)
Affinity DataIC50: 60nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM123942(US8754233, 2-(5-Amino-1H-pyrazol-4-yl)-benzothiazo...)
Affinity DataIC50: 60nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM123994(US8754233, 4-(5-Fluoro-6-methoxy-benzothiazol-2-yl...)
Affinity DataIC50: 60nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM124033(US8754233, 4-Benzothiazol-2-yl-5-piperidin-4-yl-2H...)
Affinity DataIC50: 60nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM123931(US8754233, 2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-4,...)
Affinity DataIC50: 70nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM123936(US8754233, 2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-be...)
Affinity DataIC50: 70nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM123996(US8754233, 4-(5-Fluoro-6-methoxy-benzothiazol-2-yl...)
Affinity DataIC50: 70nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM123962(US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-be...)
Affinity DataIC50: 90nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM123925(US8754233, [2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-5...)
Affinity DataIC50: 100nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM123972(US8754233, 2-{[2-(5-Amino-3-methyl-1H-pyrazol-4-yl...)
Affinity DataIC50: 100nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM123993(US8754233, 4-(5-Fluoro-6-methoxy-benzothiazol-2-yl...)
Affinity DataIC50: 100nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM124024(US8754233, 4-Benzothiazol-2-yl-5-(4-methylamino-bu...)
Affinity DataIC50: 100nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM124028(US8754233, 4-Benzothiazol-2-yl-5-furan-2-yl-2H-pyr...)
Affinity DataIC50: 100nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM124035(US8754233, 4-Benzothiazol-2-yl-5-pyridin-4-yl-2H-p...)
Affinity DataIC50: 100nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM124053(US8754233, 5-(4-Amino-phenyl)-4-benzothiazol-2-yl-...)
Affinity DataIC50: 100nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM123947(US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-5-...)
Affinity DataIC50: 130nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM123944(US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-5-...)
Affinity DataIC50: 150nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM124041(US8754233, 4-Benzothiazol-2-yl-N3-(2-ethylamino-et...)
Affinity DataIC50: 150nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM124032(US8754233, 4-Benzothiazol-2-yl-5-piperazin-1-yl-2H...)
Affinity DataIC50: 190nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM123923(US8754233, (4-Benzothiazol-2-yl-1H-pyrazol-3-yl)-[...)
Affinity DataIC50: 200nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM123948(US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-be...)
Affinity DataIC50: 200nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM123952(US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-be...)
Affinity DataIC50: 200nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIntegrin-linked protein kinase(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM123960(US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-be...)
Affinity DataIC50: 200nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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