Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase KMT5C'
LigandPNGBDBM223981(A-196 (3) | 6,7-Dichloro-N-cyclopentyl-4-(pyridin-...)
Affinity DataIC50: 144nMpH: 8.0 T: 2°CAssay Description:Experiments were performed in triplicate at room temperature with 1 h incubation of 10 μl reaction mixture in buffer of 20 mM Tris-HCl, pH 8.0, ...More data for this Ligand-Target Pair
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LigandPNGBDBM223980(6,7-Dichloro-N-cyclopentylquinolin-4-amine (2))
Affinity DataIC50: 1.20E+3nMpH: 8.0 T: 2°CAssay Description:Experiments were performed in triplicate at room temperature with 1 h incubation of 10 μl reaction mixture in buffer of 20 mM Tris-HCl, pH 8.0, ...More data for this Ligand-Target Pair
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LigandPNGBDBM223979(7-Chloro-N-cyclopentylquinolin-4-amine (1))
Affinity DataIC50: 4.80E+3nMpH: 8.0 T: 2°CAssay Description:Experiments were performed in triplicate at room temperature with 1 h incubation of 10 μl reaction mixture in buffer of 20 mM Tris-HCl, pH 8.0, ...More data for this Ligand-Target Pair
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LigandPNGBDBM223982(A-197 (4) | (6,7-Dichloro-4-(cyclopentylamino)phth...)
Affinity DataIC50: 1.00E+4nMpH: 8.0 T: 2°CAssay Description:Experiments were performed in triplicate at room temperature with 1 h incubation of 10 μl reaction mixture in buffer of 20 mM Tris-HCl, pH 8.0, ...More data for this Ligand-Target Pair
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LigandPNGBDBM50009672(AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SUV420H2 (unknown origin) by HMT assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50051117(CHEMBL3318285)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of SUV420H2 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate...More data for this Ligand-Target Pair
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LigandPNGBDBM50063670(CHEMBL3397332)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of SUV420H2 (unknown origin) by HMT assayMore data for this Ligand-Target Pair
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PubMed