Report error Found 6430 Enz. Inhib. hit(s) with Target = 'Histone acetyltransferase'
Affinity DataKd: 400nMT: 2°CAssay Description:The p300 activity assays were performed by a colorimetric kit (JM-K322-100, MBL) using active recombinant p300/HAT as positive control and acetyl-CoA...More data for this Ligand-Target Pair
Affinity DataKd: 250nMT: 2°CAssay Description:The p300 activity assays were performed by a colorimetric kit (JM-K322-100, MBL) using active recombinant p300/HAT as positive control and acetyl-CoA...More data for this Ligand-Target Pair
Affinity DataKd: 100nMT: 2°CAssay Description:The p300 activity assays were performed by a colorimetric kit (JM-K322-100, MBL) using active recombinant p300/HAT as positive control and acetyl-CoA...More data for this Ligand-Target Pair
Affinity DataKd: 390nMT: 2°CAssay Description:The p300 activity assays were performed by a colorimetric kit (JM-K322-100, MBL) using active recombinant p300/HAT as positive control and acetyl-CoA...More data for this Ligand-Target Pair
Affinity DataKd: 810nMT: 2°CAssay Description:The p300 activity assays were performed by a colorimetric kit (JM-K322-100, MBL) using active recombinant p300/HAT as positive control and acetyl-CoA...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to human PCAF (G715 to D831 residues) expressed in mammalian expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to human GCN5L2 (E726 to K837 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 87nMAssay Description:Binding affinity to human EP300 (A1040 to G1161 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.60E+3nMAssay Description:Binding affinity to N-terminal His6-tagged KAT8 catalytic domain (125 to 458 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) by is...More data for this Ligand-Target Pair
Affinity DataKd: 700nMAssay Description:Binding affinity to N-terminal His6-tagged KAT8 catalytic domain (125 to 458 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) in pr...More data for this Ligand-Target Pair
Affinity DataKd: 100nMAssay Description:Binding affinity to human N-terminal His-tagged PCAF by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 4.94E+3nMAssay Description:Binding affinity to N-terminal 6His tagged KAT8 (173 to 458 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as dissociati...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 7.80E+3nMAssay Description:Binding affinity to human N-terminal His-tagged PCAF by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 1.40nMAssay Description:Binding affinity to human Biotin-Avi-P300 using Neutravidin as ligand measured by Surface Plasmon Resonance methodMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataEC50: 1.90nMAssay Description:Induction of p300 degradation in human RS4-11 cells incubated for 4 hrs by Western blot assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: <1.00E+5nMAssay Description:Binding affinity to KAT2B in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assayMore data for this Ligand-Target Pair
Affinity DataKd: 6.60E+3nMAssay Description:Binding affinity to HAT p300 catalytic domain by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 128nMAssay Description:Binding affinity to human N-terminal His-tagged PCAF by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 410nMAssay Description:Binding affinity to human partial length GCN5L2 (E726 to K837 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human partial length GCN5L2 (E726 to K837 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human N-terminal His-tagged PCAF by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 12nMAssay Description:Binding affinity to PCAF (unknown origin) by BROMOscan methodMore data for this Ligand-Target Pair
Affinity DataKd: 1.08E+6nMAssay Description:Binding affinity to human His6-tagged PCAF expressed in Escherichia coli BL21(DE3)-R3 using 3% DMSO by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 820nMAssay Description:Binding affinity to human N-terminal His-tagged PCAF by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 2.40E+3nMAssay Description:Binding affinity to human N-terminal His-tagged PCAF by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length EP300 (A1040 to G1161 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.04E+3nMAssay Description:Binding affinity to N-terminal 6His tagged KAT8 (173 to 458 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as dissociati...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length GCN5L2 (E726 to K837 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 31nMAssay Description:Binding affinity to EP300 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Affinity DataKd: 1.66E+5nMAssay Description:Binding affinity to human His6-tagged PCAF expressed in Escherichia coli BL21(DE3)-R3 using 1% DMSO by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length GCN5L2 (E726 to K837 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 935nMAssay Description:Binding affinity to human N-terminal His-tagged PCAF by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 370nMAssay Description:Binding affinity to PCAF (unknown origin) by BROMOscan methodMore data for this Ligand-Target Pair
Affinity DataKd: 16nMAssay Description:Binding affinity to p300 (unknown origin) by fluorescence anisotrophyMore data for this Ligand-Target Pair
Affinity DataKd: 1.19E+3nMAssay Description:Binding affinity to human N-terminal His-tagged PCAF by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 167nMAssay Description:Inhibition of human p300 expressed in competent escherichia coli BL21(DE3)-R3-pRARE2 cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: <1nMAssay Description:Binding affinity to human partial length GCN5L2 (E726 to K837 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 14nMAssay Description:Binding affinity to PCAF (unknown origin) by BROMOscan methodMore data for this Ligand-Target Pair
Affinity DataKd: 240nMAssay Description:Binding affinity to human EP300 assessed as dissociation constant by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.60E+5nMAssay Description:Binding affinity to human His6-tagged PCAF expressed in Escherichia coli BL21(DE3)-R3 using 0.5% DMSO by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 45nMAssay Description:Binding affinity to p300 (unknown origin) by ITC assayMore data for this Ligand-Target Pair
Affinity DataKd: 7.10E+4nMAssay Description:Binding affinity to human partial length EP300 (A1040 to G1161 residues) expressed in bacterial expression system by BROMOscan methodMore data for this Ligand-Target Pair
Affinity DataKd: >5.00E+3nMAssay Description:Binding affinity to human PCAF (G715 to D831 residues) expressed in bacterial expression system by BROMOScan assayMore data for this Ligand-Target Pair
Affinity DataKd: <1.00E+5nMAssay Description:Binding affinity to KAT2A in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assayMore data for this Ligand-Target Pair
Affinity DataKd: 345nMAssay Description:Binding affinity to recombinant P300 CH1 domain assessed as dissociation constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Affinity DataKd: 2.50E+5nMAssay Description:Binding affinity to human His6-tagged PCAF expressed in Escherichia coli BL21(DE3)-R3 using methanol by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 140nMAssay Description:Binding affinity to human N-terminal His-tagged PCAF by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 1.04E+5nMAssay Description:Binding affinity to human His6-tagged PCAF expressed in Escherichia coli BL21(DE3)-R3 using 0.5% DMSO by SPR assayMore data for this Ligand-Target Pair
TargetHistone acetyltransferase type B catalytic subunit(Homo sapiens)
Wayne State University
Curated by ChEMBL
Wayne State University
Curated by ChEMBL
Affinity DataKd: 5.20E+3nMAssay Description:Binding affinity to CM5 sensor chip immobilized C-terminal FLAG tagged full length human HAT1/Rbap46 assessed as dissociation constant by SPR analysi...More data for this Ligand-Target Pair
Affinity DataKd: <3.02E+4nMAssay Description:Binding affinity to human partial length DNA-tagged EP300 expressed in bacteria by BROMOscan methodMore data for this Ligand-Target Pair
