Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor-like protein'
TargetHepatocyte growth factor-like protein(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50: 177nMAssay Description:Inhibition of MST1 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetHepatocyte growth factor-like protein(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM185674(Rebastinib | 4-[4-[(5-tert-butyl-2-quinolin-6-ylpy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human wild type MST1 using RB-CTF as substrate preincubated for 2 hrs followed by ATP addition and measured every 2 mins for 2.5 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHepatocyte growth factor-like protein(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235816(CHEMBL4069365)
Affinity DataIC50: 2.32E+3nMAssay Description:Inhibition of MST1 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetHepatocyte growth factor-like protein(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235817(CHEMBL4078893)
Affinity DataIC50: 9.08E+3nMAssay Description:Inhibition of MST1 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetHepatocyte growth factor-like protein(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50391802(CHEMBL2146883 | cobimetinib | (3,4-difluoro-2-(2-f...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MST1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHepatocyte growth factor-like protein(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MST1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHepatocyte growth factor-like protein(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235833(CHEMBL4062803)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MST1 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetHepatocyte growth factor-like protein(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235820(CHEMBL4066664)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MST1 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetHepatocyte growth factor-like protein(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50599287(CHEMBL5183592 | US12318398, Compound 25)
Affinity DataIC50: 2.27E+4nMAssay Description:The IC50 values of the compounds against MST1 were determined. The protein kinase MST1 and the substrate were obtained from commercial sources.5.4 μL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2025
Entry Details
Go to US Patent

TargetHepatocyte growth factor-like protein(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50599294(CHEMBL5207166 | US12318398, Compound 1)
Affinity DataIC50: 2.30E+4nMAssay Description:The IC50 values of the compounds against MST1 were determined. The protein kinase MST1 and the substrate were obtained from commercial sources.5.4 μL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2025
Entry Details
Go to US Patent

TargetHepatocyte growth factor-like protein(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM746805(US12318398, Compound 32)
Affinity DataIC50: 3.16E+4nMAssay Description:The IC50 values of the compounds against MST1 were determined. The protein kinase MST1 and the substrate were obtained from commercial sources.5.4 μL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/29/2025
Entry Details
Go to US Patent

TargetHepatocyte growth factor-like protein(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM746807(US12318398, Compound 38)
Affinity DataIC50: 5.16E+4nMAssay Description:The IC50 values of the compounds against MST1 were determined. The protein kinase MST1 and the substrate were obtained from commercial sources.5.4 μL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/29/2025
Entry Details
Go to US Patent

TargetHepatocyte growth factor-like protein(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50599290(CHEMBL5204087 | US12318398, Compound 22)
Affinity DataIC50: 5.63E+4nMAssay Description:The IC50 values of the compounds against MST1 were determined. The protein kinase MST1 and the substrate were obtained from commercial sources.5.4 μL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2025
Entry Details
Go to US Patent

TargetHepatocyte growth factor-like protein(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50599285(CHEMBL5200209 | US12318398, Compound 21)
Affinity DataIC50: 7.53E+4nMAssay Description:The IC50 values of the compounds against MST1 were determined. The protein kinase MST1 and the substrate were obtained from commercial sources.5.4 μL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2025
Entry Details
Go to US Patent

TargetHepatocyte growth factor-like protein(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50599278(CHEMBL5187804 | US12318398, Compound 16)
Affinity DataIC50: 7.67E+4nMAssay Description:The IC50 values of the compounds against MST1 were determined. The protein kinase MST1 and the substrate were obtained from commercial sources.5.4 μL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2025
Entry Details
Go to US Patent

TargetHepatocyte growth factor-like protein(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50599303(CHEMBL5170557 | US12318398, Compound 33)
Affinity DataIC50: 7.96E+4nMAssay Description:The IC50 values of the compounds against MST1 were determined. The protein kinase MST1 and the substrate were obtained from commercial sources.5.4 μL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2025
Entry Details
Go to US Patent

TargetHepatocyte growth factor-like protein(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50599295(CHEMBL5188315 | US12318398, Compound 20)
Affinity DataIC50: 8.79E+4nMAssay Description:The IC50 values of the compounds against MST1 were determined. The protein kinase MST1 and the substrate were obtained from commercial sources.5.4 μL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2025
Entry Details
Go to US Patent

TargetHepatocyte growth factor-like protein(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM745536(US12318398, Compound 38)
Affinity DataIC50: 9.87E+4nMAssay Description:The IC50 values of the compounds against MST1 were determined. The protein kinase MST1 and the substrate were obtained from commercial sources.5.4 μL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/29/2025
Entry Details
Go to US Patent

TargetHepatocyte growth factor-like protein(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50599297(CHEMBL5170173 | US12318398, Compound 7)
Affinity DataIC50: 1.03E+5nMAssay Description:The IC50 values of the compounds against MST1 were determined. The protein kinase MST1 and the substrate were obtained from commercial sources.5.4 μL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2025
Entry Details
Go to US Patent

TargetHepatocyte growth factor-like protein(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM746804(US12318398, Compound 27)
Affinity DataIC50: 1.13E+5nMAssay Description:The IC50 values of the compounds against MST1 were determined. The protein kinase MST1 and the substrate were obtained from commercial sources.5.4 μL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/29/2025
Entry Details
Go to US Patent

TargetHepatocyte growth factor-like protein(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50583996(CHEMBL4554938 | US12318398, Compound XMU-MP-1)
Affinity DataIC50: 1.21E+5nMAssay Description:The IC50 values of the compounds against MST1 were determined. The protein kinase MST1 and the substrate were obtained from commercial sources.5.4 μL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2025
Entry Details
Go to US Patent

TargetHepatocyte growth factor-like protein(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50599299(CHEMBL5182825 | US12318398, Compound 14)
Affinity DataIC50: 1.29E+5nMAssay Description:The IC50 values of the compounds against MST1 were determined. The protein kinase MST1 and the substrate were obtained from commercial sources.5.4 μL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2025
Entry Details
Go to US Patent

TargetHepatocyte growth factor-like protein(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50599281(CHEMBL5201386 | US12318398, Compound 11)
Affinity DataIC50: 1.34E+5nMAssay Description:The IC50 values of the compounds against MST1 were determined. The protein kinase MST1 and the substrate were obtained from commercial sources.5.4 μL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2025
Entry Details
Go to US Patent

TargetHepatocyte growth factor-like protein(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50599271(CHEMBL5198452 | US12318398, Compound 19)
Affinity DataIC50: 1.37E+5nMAssay Description:The IC50 values of the compounds against MST1 were determined. The protein kinase MST1 and the substrate were obtained from commercial sources.5.4 μL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2025
Entry Details
Go to US Patent

TargetHepatocyte growth factor-like protein(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50599298(CHEMBL5180293 | US12318398, Compound 15)
Affinity DataIC50: 1.41E+5nMAssay Description:The IC50 values of the compounds against MST1 were determined. The protein kinase MST1 and the substrate were obtained from commercial sources.5.4 μL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2025
Entry Details
Go to US Patent

TargetHepatocyte growth factor-like protein(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM745533(US12318398, Compound 27)
Affinity DataIC50: 1.43E+5nMAssay Description:The IC50 values of the compounds against MST1 were determined. The protein kinase MST1 and the substrate were obtained from commercial sources.5.4 μL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/29/2025
Entry Details
Go to US Patent

TargetHepatocyte growth factor-like protein(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM744759(US12318398, Compound 10)
Affinity DataIC50: 1.97E+5nMAssay Description:The IC50 values of the compounds against MST1 were determined. The protein kinase MST1 and the substrate were obtained from commercial sources.5.4 μL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/29/2025
Entry Details
Go to US Patent

TargetHepatocyte growth factor-like protein(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50599275(CHEMBL5207430 | US12318398, Compound 17)
Affinity DataIC50: 2.06E+5nMAssay Description:The IC50 values of the compounds against MST1 were determined. The protein kinase MST1 and the substrate were obtained from commercial sources.5.4 μL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2025
Entry Details
Go to US Patent