Report error Found 602 Enz. Inhib. hit(s) with Target = 'Hematopoietic prostaglandin D synthase'
Affinity DataKd: 44nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 9.5nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 50nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 60nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 300nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 200nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 1.00E+3nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: <2.00E+4nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 60nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: <100nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 200nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 1.40E+4nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 400nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 1.30E+4nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 1.00E+3nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 200nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 2.00E+3nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 400nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 1.00E+4nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 1.40E+5nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 800nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataEC50: 350nMAssay Description:Inhibition HPGDS in human MEG01 cells assessed as reduction in PGD2 production incubated for 30 mins followed by stimulation with 5 uM ionomycin for ...More data for this Ligand-Target Pair
Affinity DataEC50: 110nMAssay Description:Inhibition HPGDS in human MEG01 cells assessed as reduction in PGD2 production incubated for 30 mins followed by stimulation with 5 uM ionomycin for ...More data for this Ligand-Target Pair
Affinity DataEC50: 74nMAssay Description:Inhibition HPGDS in human MEG01 cells assessed as reduction in PGD2 production incubated for 30 mins followed by stimulation with 5 uM ionomycin for ...More data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Inhibition HPGDS in human MEG01 cells assessed as reduction in PGD2 production incubated for 30 mins followed by stimulation with 5 uM ionomycin for ...More data for this Ligand-Target Pair
Affinity DataEC50: 35nMAssay Description:Inhibition HPGDS in human MEG01 cells assessed as reduction in PGD2 production incubated for 30 mins followed by stimulation with 5 uM ionomycin for ...More data for this Ligand-Target Pair
Affinity DataKd: 210nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 300nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 35nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 12nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 20nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 650nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 340nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 570nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 51nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 23nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 0.140nMAssay Description:Binding affinity to full length recombinant human N-terminal His6-tagged H-PGDS expressed in Escherichia coli BL21(DE3) by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 0.370nMAssay Description:Binding affinity to full length recombinant human N-terminal His6-tagged H-PGDS expressed in Escherichia coli BL21(DE3) by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 0.5nMAssay Description:Binding affinity to full-length human His6-tagged HPGDS expressed in Escherichia coli BL21 (DE3) by tryptophan fluorescence quenching assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataEC50: 160nMAssay Description:Inhibition of H-PGDS in rat RBL cells assessed as reduction in A23187-induced PGD2 production pretreated for 30 mins followed by A23187 addition for ...More data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+4nMAssay Description:Inhibition of H-PGDS in rat RBL cells assessed as reduction in A23187-induced PGD2 production pretreated for 30 mins followed by A23187 addition for ...More data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Inhibition of H-PGDS in rat RBL cells assessed as reduction in A23187-induced PGD2 production pretreated for 30 mins followed by A23187 addition for ...More data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of H-PGDS in rat RBL cells assessed as reduction in A23187-induced PGD2 production pretreated for 30 mins followed by A23187 addition for ...More data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of H-PGDS in rat RBL cells assessed as reduction in A23187-induced PGD2 production pretreated for 30 mins followed by A23187 addition for ...More data for this Ligand-Target Pair
Affinity DataEC50: 4.30E+3nMAssay Description:Inhibition of H-PGDS in rat RBL cells assessed as reduction in A23187-induced PGD2 production pretreated for 30 mins followed by A23187 addition for ...More data for this Ligand-Target Pair
Affinity DataEC50: 3.20E+3nMAssay Description:Inhibition of H-PGDS in rat RBL cells assessed as reduction in A23187-induced PGD2 production pretreated for 30 mins followed by A23187 addition for ...More data for this Ligand-Target Pair
Affinity DataEC50: 740nMAssay Description:Inhibition of H-PGDS in rat RBL cells assessed as reduction in A23187-induced PGD2 production pretreated for 30 mins followed by A23187 addition for ...More data for this Ligand-Target Pair
Affinity DataEC50: 190nMAssay Description:Inhibition of H-PGDS in rat RBL cells assessed as reduction in A23187-induced PGD2 production pretreated for 30 mins followed by A23187 addition for ...More data for this Ligand-Target Pair
Affinity DataEC50: 3.90E+4nMAssay Description:Inhibition of H-PGDS in rat RBL cells assessed as reduction in A23187-induced PGD2 production pretreated for 30 mins followed by A23187 addition for ...More data for this Ligand-Target Pair
Affinity DataEC50: 150nMAssay Description:Inhibition of H-PGDS in rat RBL cells assessed as reduction in A23187-induced PGD2 production pretreated for 30 mins followed by A23187 addition for ...More data for this Ligand-Target Pair
